Prurito gambe e diabete
What are some key differences between a pregnancy and maternity specialist and a general obstetrician/gynecologist?
2024.06.01 07:36 drchitra What are some key differences between a pregnancy and maternity specialist and a general obstetrician/gynecologist?
The primary differences between a pregnancy and maternity specialist and a general obstetrician/gynecologist (OB/GYN) revolve around their focus areas, training, and the types of care they provide. Here are the key distinctions:
submitted by drchitra to u/drchitra [link] [comments]
Pregnancy and Maternity Specialist
Focus:- Primarily focuses on the care of pregnant women, prenatal care, childbirth, and postpartum care.
- Specializes in managing high-risk pregnancies, complications during pregnancy, and fetal medicine.
- Additional training in maternal-fetal medicine (MFM) or perinatology after completing an OB/GYN residency.
- Certification by relevant boards such as the American Board of Obstetrics and Gynecology (ABOG) with a subspecialty in Maternal-Fetal Medicine.
- Provides specialized care for complex pregnancies, including those involving chronic health conditions, multiple gestations (twins, triplets, etc.), and fetal abnormalities.
- Often works in collaboration with other specialists such as neonatologists, pediatric surgeons, and genetic counselors.
- May perform advanced diagnostic procedures like detailed ultrasounds, fetal echocardiograms, and genetic testing.
- Manages conditions like preeclampsia, gestational diabetes, preterm labor, and intrauterine growth restriction (IUGR).
General Obstetrician/Gynecologist (OB/GYN)
Focus:- Provides comprehensive care for women’s health, including reproductive health, pregnancy, childbirth, and gynecological issues.
- Treats a wide range of conditions from adolescence through menopause and beyond.
- Completes a residency in obstetrics and gynecology.
- Certified by boards like the American Board of Obstetrics and Gynecology (ABOG).
- Offers routine prenatal care, delivers babies, and manages normal and low-risk pregnancies.
- Provides general gynecological services such as annual exams, contraceptive counseling, and treatment of gynecological conditions (e.g., fibroids, endometriosis, ovarian cysts).
- Performs routine obstetric procedures such as prenatal ultrasounds, amniocentesis, and Cesarean sections.
- Conducts gynecological surgeries like hysterectomies, laparoscopies, and treatment of pelvic floor disorders.
Summary
While both specialists play crucial roles in women’s reproductive health, a pregnancy and maternity specialist (MFM) is more focused on high-risk pregnancies and advanced fetal care, requiring additional training and expertise. In contrast, a general OB/GYN provides broader care encompassing both obstetrics and gynecology, handling a wide range of women’s health issues throughout different life stages.v2024.06.01 05:48 MiroLol_ Benefícios e mitos sobre o café
Melhora o Desempenho Físico: A cafeína no café aumenta a adrenalina no sangue, o que ajuda a melhorar o desempenho em atividades físicas intensas.
Aumenta a Energia e o Foco: A cafeína é um estimulante que melhora o foco, a concentração e reduz o cansaço.
Rico em Antioxidantes: O café tem muitos antioxidantes, que ajudam a combater os danos no corpo e podem reduzir o risco de várias doenças.
Reduz o Risco de Doenças: Tomar café regularmente pode ajudar a diminuir o risco de doenças como Parkinson, Alzheimer, e diabetes tipo 2.
Saúde do Fígado: O café pode proteger o fígado contra doenças como cirrose e câncer de fígado.
Melhora a Saúde Mental: Alguns estudos mostram que o café pode ajudar a reduzir o risco de depressão e melhorar o humor.
Ajuda a Queimar Gordura: A cafeína pode aumentar o metabolismo e ajudar na queima de gordura.
Reduz o Risco de AVC: Consumir café moderadamente pode diminuir o risco de acidente vascular cerebral (AVC).
Mitos sobre o Café
Café é Tão Viciante Quanto Drogas: A cafeína pode causar dependência leve, mas não é viciante como drogas pesadas.
Café é Ruim para o Coração: Beber café com moderação não faz mal para o coração. Alguns estudos até dizem que pode ser bom para a saúde do coração.
Café Impede o Crescimento: Não há provas de que o café afeta o crescimento das crianças.
Café Causa Osteoporose: Beber café moderadamente não aumenta o risco de osteoporose, desde que você consuma cálcio suficiente.
Café Causa Úlceras e Refluxo: O café pode aumentar o ácido no estômago, mas não causa úlceras ou refluxo. Pode piorar os sintomas em algumas pessoas.
Descafeinado Não Tem Cafeína: O café descafeinado ainda tem um pouco de cafeína.
Café Não Tem Nutrientes: O café tem pequenas quantidades de vitaminas e minerais, como vitamina B2, B5, manganês, potássio, magnésio e niacina.
submitted by MiroLol_ to cafebrasil [link] [comments]
Aumenta a Energia e o Foco: A cafeína é um estimulante que melhora o foco, a concentração e reduz o cansaço.
Rico em Antioxidantes: O café tem muitos antioxidantes, que ajudam a combater os danos no corpo e podem reduzir o risco de várias doenças.
Reduz o Risco de Doenças: Tomar café regularmente pode ajudar a diminuir o risco de doenças como Parkinson, Alzheimer, e diabetes tipo 2.
Saúde do Fígado: O café pode proteger o fígado contra doenças como cirrose e câncer de fígado.
Melhora a Saúde Mental: Alguns estudos mostram que o café pode ajudar a reduzir o risco de depressão e melhorar o humor.
Ajuda a Queimar Gordura: A cafeína pode aumentar o metabolismo e ajudar na queima de gordura.
Reduz o Risco de AVC: Consumir café moderadamente pode diminuir o risco de acidente vascular cerebral (AVC).
Mitos sobre o Café
Café é Tão Viciante Quanto Drogas: A cafeína pode causar dependência leve, mas não é viciante como drogas pesadas.
Café é Ruim para o Coração: Beber café com moderação não faz mal para o coração. Alguns estudos até dizem que pode ser bom para a saúde do coração.
Café Impede o Crescimento: Não há provas de que o café afeta o crescimento das crianças.
Café Causa Osteoporose: Beber café moderadamente não aumenta o risco de osteoporose, desde que você consuma cálcio suficiente.
Café Causa Úlceras e Refluxo: O café pode aumentar o ácido no estômago, mas não causa úlceras ou refluxo. Pode piorar os sintomas em algumas pessoas.
Descafeinado Não Tem Cafeína: O café descafeinado ainda tem um pouco de cafeína.
Café Não Tem Nutrientes: O café tem pequenas quantidades de vitaminas e minerais, como vitamina B2, B5, manganês, potássio, magnésio e niacina.
2024.06.01 02:54 nctwje Idosa Ajudemserena no twitter pode ser um golpe bem articulado da filha que tinha um fake conhecido no Orkut há 20 anos
Fiquei pensando em postar isso há alguns dias mas acho que agora é o momento ideal, pois imagino que aqui possa ter ex usuários do Orkut, usuários do twitter e até mesmo pessoas que possam ter doado pra idosa. Também servindo como alerta pra algumas pessoas. Esse vai ser um post longo, vou colocar o máximo de informações que encontrei. Vi um post sobre isso aqui no reddit há muitos anos e há 6 meses fizeram um aqui que teve pouco alcance. Queria postar no brasil para alcançar mais pessoas visto que ela segue pedindo dinheiro pras pessoas e essas mandam mas é necessário alguns karmas lá para postar então decidi postar somente aqui. Tentei linkar todos os prints que encontrei sobre o que estou contando nesse post.
Vamos lá, talvez em algum momento nos últimos 4-5 anos vocês tenham se deparado com o perfil @ ajudemserena no twitter. Se trata de, supostamente, uma idosa que vive em condições insalubres e, supostamente, não tem condições físicas para trabalhar por ter diabetes (sim, você não leu errado, ela diz ser incapaz pq tem diabetes tipo 2) e que surgiu há muitos anos pois sua cadela (serena) estava doente e precisava de ajuda com os custos dos tratamentos. A cadela, que já era idosa com cerca de 15 anos, não sobreviveu mesmo com todo o dinheiro arrecadado pela senhora (quase 10 mil reais, se contar apenas as vakinhas, podendo ser mais) e então a mesma começou a pedir dinheiro para se manter pois havia vendido muito do que tinha, e tinha pouco, para custear a ajuda veterinária. Ela também pede dinheiro para comprar remédios, que são gratuitos pelo SUS. E lá se foram quase 5 anos de pedido por DINHEIRO. sim, dinheiro. ela não aceita outro tipo de ajuda.
Nos últimos dias, após um rapaz fazer uma thread contando a condição da idosa e pedir que as pessoas a divulgassem, muitas pessoas começaram a questionar a veracidade da história dela. Ainda que ela poste videos, fotos e até mesmo faça algumas lives, a conta não bate e os relatos indicam um possível golpe que já dura anos. Algumas pessoas deram relatos sobre como tentaram encaminhar ela pra ajudas governamentais ou de ONGs e que ela negou, inclusive uma moça que trabalhava com o CRAS perguntou a cidade que ela reside pra pedir que alguém de lá fizesse uma visita e levasse mantimentos e produtos de higiene, o que ela negou. Outros relatos contam como sempre ela tinha um novo ''propósito", assim que dá 00h00 ela começa a postar sobre não ter conseguido nenhum dinheiro, não ter dinheiro pra comprar frutas, não ter dinheiro pra comprar água e então faz centenas de tweets com um comportamento muito suspeito, como se fosse um bot programado. Tweets como "preciso de 20 reais, alguém pode me dar 20 reais? qualquer centavo ajuda" ou "preciso de 46 reais hoje, por favor alguém pode mandar?" todos de forma repetida diversas vezes, o que acabava convencendo pessoas a mandarem valores pra ela (inclusive maiores do que o que ela pedia) e ela então deletava o post pra algumas horas (às vezes minutos) depois postar NOVAMENTE que não tinha recebido nenhum valor, nenhuma ajuda. nenhum centavo se quer. E isso se repete todos os dias. As pessoas mandam dinheiro quando ela posta relatos desesperada, ela apaga os relatos (onde inclusive as pessoas costumavam colocar comprovantes antes dela bloquear os comentários) e posta novamente pedindo a mesma quantia ou até maior.
Em algum momento do ano passado, essa suposta idosa abriu uma vakinha pedindo 200 MIL REAIS pra comprar uma casa própria. Ela diz que a casa em que mora agora não é dela e está em inventário, pois é da mãe falecida. Ela também afirma que os irmãos que tem nunca a ajudaram, não querem realizar o inventário e que tem medo de ser despejada da casa algum dia. A vakinha já arrecadou quase 50 mil, e isso é só na vakinha (site) pois ninguém sabe ao certo quanto dinheiro essa mulher conseguiu durante esses anos. E agora a gente entra numa parte desse tópico que torna a história muito interessante:
A Alcina (idosa da conta) sempre disse que tinha filhos. Dois filhos. Ela afirmou diversas vezes que esses filhos tem 'sérios problemas de saúde' e que isso os impede de trabalhar, eu não encontrei ela dizendo se mora com ambos mas eu imagino que sim. Em outros posts, foi relatado por ela que o filho tinha formação e já trabalhou com T.I, sobre a filha ela não chegou a dizer nada sobre a formação mas recentemente afirmou que ambos filhos tem depressão e problemas com ansiedade. Um usuário do twitter encontrou a informação de que a filha é formada em administração. Nessa semana ela afirmou que a filha é obesa e que pesa 140kg o que a impede de exercer algum trabalho pois não consegue se movimentar, disse que ela tem diversas feridas no corpo por conta do peso e por aí vai. Nós vamos focar primeiro na filha. A Alcina publica sempre o próprio CPF, o que facilitou muito para que pessoas na rede social em que ela pede dinheiro procurassem informações sobre ela. Não vou usar mais que um nome e sobrenome aqui para evitar grandes problemas.
Utilizando do CPF, foi encontrado que a filha dela se chama Amanda. Dona Alcina tem um sobrenome muito específico, não muito comum; Ulm. Em algumas pesquisas acharam um video de 2012 da Amanda Ulm no programa do Luciano Hulk, o qual ela gravou um vídeo mostrando sua coleção de revistas e itens do ator Taylor Lautner (de Crepúsculo) e pedia para conhece-lo (na época, o programa Caldeirão tinha um seguimento onde levavam fãs para conhecerem seus ídolos quando esses estavam no Brasil). Esse vídeo é público e de domínio da Rede Globo, é possível encontrar no Globoplay em um dos trechos de programas de outubro de 2012 do Caldeirão do Hulk mas caso não queiram procurar cliquem aqui. O resgate desse vídeo nos arquivos do programa de 12 anos atrás foi o primeiro passo para entender qual o envolvimento da Amanda em tudo isso. Procurando por perfis antigos pertencentes a Amanda, foi encontrado no twitter uma conta chamada amandaulmfan, posteriormente alguns outros perfis relacionados incluindo o de uma suposta amiga da Amanda, e do Felipe, que seria o irmão dela e filho da Alcina. SERIA pois não há nenhum indicio de que ele de fato exista. Entre tweets antigos, eu encontrei um post chamando a Amanda de irmã do Felipe, a mesma coisa para outras contas que se referiam a ela como a irmã e se diziam ser amigas do cara. A conta do suposto Felipe não foi difícil de encontrar, inclusive tinha um tweet de 2023 lá quando eu abri, o que me indicou que ainda tivesse acesso e isso foi confirmado hoje quando a conta se tornou privada. Algumas coisas curiosas sobre a conta: existem tweets de uma das fiéis defensoras da dona Alcina chamada Ana, que diz não ter nenhum parentesco e ser apenas uma pessoa muito empática com a idosa, interagindo com a conta KingLautner em 2015, anos antes da Alcina surgir no twitter. Esse perfil do irmão também tem algumas outras interações que me chamaram atenção há dois dias quando as vi, como tweets relacionados a "fake" e conversas que citavam a Alcina. Até que ontem a belle hendges @ bucherwurm postou que a Amanda Ulm é conhecida entre a galera que usava fakes no orkut pois ela enganou (literalmente) milhares de pessoas se passando por um menino. Sim. Ela tinha um fake do Taylor Lautner (e quem viveu sabe, os adolescentes usavam os fakes e sabiam que eram fakes, mas geralmente mentir o próprio gênero era um problemão que acontecia bastante pq fanboy recebia muito mais atenção nas comunidades na época) e se passava por um rapaz. O perfil era tão conhecido que existiam comunidades, milhares de pessoas se dedicando ao fake da Amanda, ela era extremamente conhecida e vivia nas listas na época, e você pode pensar que tudo isso é uma grande coincidência mas, de novo, o perfil da Ana que vive para defender a Dona Alcina das acusações de golpe é encontrado se atrelando a todo esse emaranhado ao responder um tweet ofendendo o Taylor Cent de 2012 em 2020, OITO ANOS DEPOIS. Logo descobriram que o aniversário da AMANDA e do FELIPE é no mesmo dia, poderiam ser gêmeos? Talvez. Em uma ask de anos atrás, o tal Felipe diz ser gêmeo. Talvez ele exista e não tenha relação com nada disso, mas por hora vamos colocar como uma pessoa inexistente pois hoje a dona Alcina apagou TODOS os tweets relacionado ao seu filho. E falando dos filhos, a cadela Serena que faleceu há bastante tempo é também citada no ask.fm do Felipe/Amanda e nesse mesmo ask você encontra ela respondendo que é fã de iCarly e outras coisas, o que também leva a relação de compras feitas no CPF da Alcina recentemente (dvds originais de iCarly), informação encontrada por alguém no twitter.
Quando os perfis no twitter começaram a questionar a história dessa idosa, ela passou a ameaçar as pessoas de que iria denunciá-los a policia, mas ela também tentou justificar muitas coisas. Com o sobrenome dela, foi fácil encontrar parentes. O sobrenome ULM é de pessoas muito poderosas de Salvador na Bahia, onde ela reside. O pai dessa senhora foi Armando Ulm, ex delegado e que foi vereador nos anos 70. A irmã de dona Alcina foi encontrada no facebook e instagram, e ao conversar com o perfil Brinozo, ela afirmou que se ela está utilizando o nome para dar golpes ela (irmã) não sabe de nada. Essa mesma irmã foi detida em 2014 por tráfico de drogas então por isso foi fácil encontra-la, mas outras pessoas da familia também não foram difíceis. Duas pessoas de Salvador com o sobrenome Ulm são donos/sócios de uma empresa que promove eventos como shows e afins na capital, incluindo o famoso Camarote Brahma Salvador. Ontem a Alcina afirmou no twitter que nunca negou que tivesse familia e que o perfil kawoshinudes estava arquitetando todos esses ataques há muito tempo. Passou quase 1h em live falando com uma parede e afirmando que iria abrir um B.O contra o Brinozo e kawoshinudes e supostamente fez isso hoje. Outra coisa interessante é que desde que chamaram a atenção pro fato dos tweets parecerem todos feitos por bot, com curtos períodos (as vezes postados no mesmo minuto) mesmo sendo meio longos pra uma idosa digitar tão rápido, ela parou de postar como fazia e apagou todos os tweets de spam pedindo dinheiro. Além disso, o perfil dela é verificado o que dificulta qualquer denuncia por spam, quem paga o twitter premium pra uma senhora que (segundo ela) quase passa fome? ela diz que uma "boa pessoa" paga pra ajuda-la, pois aparentemente ter selo de verificação é uma das prioridades. O perfil que ela indicou dizendo ser quem pagou o verificado foi desativado. Ela também tem uma legião de perfis de engajamento, além da Ana que já citei, alguns outros com comportamento idêntico vivem para engajar os tweets da idosa e para atacar quem quer que questione a veracidade das histórias dela. Quando no ano passado uma vizinha apareceu no twitter afirmando que a idosa não tem porque pedir dinheiro pois vive bem e tem três imóveis, duas das principais contas atacaram a mulher e aparentemente alguém foi até a casa de uma outra vizinha para pedir esclarecimentos de porque ela estava tentando atacar a Alcina (vocês podem ver neste perfil, clicando pra visualizar as respostas)
Por fim, quero citar novamente que a idosa/amanda se nega a aceitar ajuda que não seja em dinheiro. No ano passado uma pessoa tentou ajudar ela indicando que ela procurasse uma ONG que ajuda mulheres, tanto na DM como em post público, a Alcina não respondeu a DM e apagou o post onde a moça falou sobre a ONG nas respostas. Esse comportamento se repete diversas vezes, uma advogada tentou ajudar ela com a questão da água cortada (ela diz que está há anos sem água encanada) e disse pra ela que não iria cobrar por nada, só queria ajudar. A Alcina BLOQUEOU a mulher. Ela também frequentemente ataca famosos que não a ajudam, mais recentemente foi Felipe Neto e Whindersson Nunes, que ela pediu dinheiro enquanto ambos estavam realizando doações para o RS, ela fez diversos posts criticando e atacando ambos por não doarem dinheiro a ela. Ela também fez durante mais de um ano uma campanha de ataques ao Alok, pois em algum momento de 2020 o DJ disse que sua equipe entraria em contato com ela para ajuda-la e foram-lhe enviados 500 reais em nome do mesmo. Ela achou pouco, acusou ele de engana-la prometendo uma casa, acusou ele de ser o responsável pela campanha dela ficar parada e sem doações. Ela acredita que pessoas famosas DEVEM a ela, e reclama de todo valor que receba de qualquer famoso, seja mil reais ou 500. Nesse momento, depois de tudo começar a tomar um pouco mais de repercussão, ela trancou o perfil então não tive mais acesso aos posts, os últimos que fez foi informando que havia aberto um BO contra usuários do twitter por "atacarem ela" (tava literalmente isso no BO) e também dizendo que a conta do Nubank dela foi bloqueada porque tentaram hackear (o que é muito conveniente uma vez que pessoas que estão nos grupos que ela cria de 'apoiadores' começaram a pedir o extrato da conta).
Enfim, eu não sei se toda essa história se trata de uma mãe e uma filha com sérios problemas psicológicos, ou se uma filha está usando da mãe idosa para aplicar um golpe pela internet, ou talvez ela simplesmente tenha decidido que é confortável viver assim durante tantos anos pois as pessoas vão dar dinheiro pra ela sempre que pedir, só sei que essa história inteira é MUITO estranha. Conheço pessoas que ajudaram há anos e que ainda hoje recebem mensagens dela pedindo por dinheiro, e nesse momento dadas todas as informações e históricos da filha, eu acredito que tudo isso tenha sido um golpe prolongado pq estava dando certo. Tomem cuidado com o que e quem vocês decidem gastar dinheiro e fazer doações na internet, ainda que exista muita gente que precise, existe na mesma medida muita gente aproveitadora. Acho que essa história tá longe de um fim, mas talvez se desenrole em breve caso continue tomando força, lembro que foi numa dessas que desmascararam aquele esquema de golpe utilizando marmitas para moradores de rua.
submitted by nctwje to golpe [link] [comments]
Vamos lá, talvez em algum momento nos últimos 4-5 anos vocês tenham se deparado com o perfil @ ajudemserena no twitter. Se trata de, supostamente, uma idosa que vive em condições insalubres e, supostamente, não tem condições físicas para trabalhar por ter diabetes (sim, você não leu errado, ela diz ser incapaz pq tem diabetes tipo 2) e que surgiu há muitos anos pois sua cadela (serena) estava doente e precisava de ajuda com os custos dos tratamentos. A cadela, que já era idosa com cerca de 15 anos, não sobreviveu mesmo com todo o dinheiro arrecadado pela senhora (quase 10 mil reais, se contar apenas as vakinhas, podendo ser mais) e então a mesma começou a pedir dinheiro para se manter pois havia vendido muito do que tinha, e tinha pouco, para custear a ajuda veterinária. Ela também pede dinheiro para comprar remédios, que são gratuitos pelo SUS. E lá se foram quase 5 anos de pedido por DINHEIRO. sim, dinheiro. ela não aceita outro tipo de ajuda.
Nos últimos dias, após um rapaz fazer uma thread contando a condição da idosa e pedir que as pessoas a divulgassem, muitas pessoas começaram a questionar a veracidade da história dela. Ainda que ela poste videos, fotos e até mesmo faça algumas lives, a conta não bate e os relatos indicam um possível golpe que já dura anos. Algumas pessoas deram relatos sobre como tentaram encaminhar ela pra ajudas governamentais ou de ONGs e que ela negou, inclusive uma moça que trabalhava com o CRAS perguntou a cidade que ela reside pra pedir que alguém de lá fizesse uma visita e levasse mantimentos e produtos de higiene, o que ela negou. Outros relatos contam como sempre ela tinha um novo ''propósito", assim que dá 00h00 ela começa a postar sobre não ter conseguido nenhum dinheiro, não ter dinheiro pra comprar frutas, não ter dinheiro pra comprar água e então faz centenas de tweets com um comportamento muito suspeito, como se fosse um bot programado. Tweets como "preciso de 20 reais, alguém pode me dar 20 reais? qualquer centavo ajuda" ou "preciso de 46 reais hoje, por favor alguém pode mandar?" todos de forma repetida diversas vezes, o que acabava convencendo pessoas a mandarem valores pra ela (inclusive maiores do que o que ela pedia) e ela então deletava o post pra algumas horas (às vezes minutos) depois postar NOVAMENTE que não tinha recebido nenhum valor, nenhuma ajuda. nenhum centavo se quer. E isso se repete todos os dias. As pessoas mandam dinheiro quando ela posta relatos desesperada, ela apaga os relatos (onde inclusive as pessoas costumavam colocar comprovantes antes dela bloquear os comentários) e posta novamente pedindo a mesma quantia ou até maior.
Em algum momento do ano passado, essa suposta idosa abriu uma vakinha pedindo 200 MIL REAIS pra comprar uma casa própria. Ela diz que a casa em que mora agora não é dela e está em inventário, pois é da mãe falecida. Ela também afirma que os irmãos que tem nunca a ajudaram, não querem realizar o inventário e que tem medo de ser despejada da casa algum dia. A vakinha já arrecadou quase 50 mil, e isso é só na vakinha (site) pois ninguém sabe ao certo quanto dinheiro essa mulher conseguiu durante esses anos. E agora a gente entra numa parte desse tópico que torna a história muito interessante:
A Alcina (idosa da conta) sempre disse que tinha filhos. Dois filhos. Ela afirmou diversas vezes que esses filhos tem 'sérios problemas de saúde' e que isso os impede de trabalhar, eu não encontrei ela dizendo se mora com ambos mas eu imagino que sim. Em outros posts, foi relatado por ela que o filho tinha formação e já trabalhou com T.I, sobre a filha ela não chegou a dizer nada sobre a formação mas recentemente afirmou que ambos filhos tem depressão e problemas com ansiedade. Um usuário do twitter encontrou a informação de que a filha é formada em administração. Nessa semana ela afirmou que a filha é obesa e que pesa 140kg o que a impede de exercer algum trabalho pois não consegue se movimentar, disse que ela tem diversas feridas no corpo por conta do peso e por aí vai. Nós vamos focar primeiro na filha. A Alcina publica sempre o próprio CPF, o que facilitou muito para que pessoas na rede social em que ela pede dinheiro procurassem informações sobre ela. Não vou usar mais que um nome e sobrenome aqui para evitar grandes problemas.
Utilizando do CPF, foi encontrado que a filha dela se chama Amanda. Dona Alcina tem um sobrenome muito específico, não muito comum; Ulm. Em algumas pesquisas acharam um video de 2012 da Amanda Ulm no programa do Luciano Hulk, o qual ela gravou um vídeo mostrando sua coleção de revistas e itens do ator Taylor Lautner (de Crepúsculo) e pedia para conhece-lo (na época, o programa Caldeirão tinha um seguimento onde levavam fãs para conhecerem seus ídolos quando esses estavam no Brasil). Esse vídeo é público e de domínio da Rede Globo, é possível encontrar no Globoplay em um dos trechos de programas de outubro de 2012 do Caldeirão do Hulk mas caso não queiram procurar cliquem aqui. O resgate desse vídeo nos arquivos do programa de 12 anos atrás foi o primeiro passo para entender qual o envolvimento da Amanda em tudo isso. Procurando por perfis antigos pertencentes a Amanda, foi encontrado no twitter uma conta chamada amandaulmfan, posteriormente alguns outros perfis relacionados incluindo o de uma suposta amiga da Amanda, e do Felipe, que seria o irmão dela e filho da Alcina. SERIA pois não há nenhum indicio de que ele de fato exista. Entre tweets antigos, eu encontrei um post chamando a Amanda de irmã do Felipe, a mesma coisa para outras contas que se referiam a ela como a irmã e se diziam ser amigas do cara. A conta do suposto Felipe não foi difícil de encontrar, inclusive tinha um tweet de 2023 lá quando eu abri, o que me indicou que ainda tivesse acesso e isso foi confirmado hoje quando a conta se tornou privada. Algumas coisas curiosas sobre a conta: existem tweets de uma das fiéis defensoras da dona Alcina chamada Ana, que diz não ter nenhum parentesco e ser apenas uma pessoa muito empática com a idosa, interagindo com a conta KingLautner em 2015, anos antes da Alcina surgir no twitter. Esse perfil do irmão também tem algumas outras interações que me chamaram atenção há dois dias quando as vi, como tweets relacionados a "fake" e conversas que citavam a Alcina. Até que ontem a belle hendges @ bucherwurm postou que a Amanda Ulm é conhecida entre a galera que usava fakes no orkut pois ela enganou (literalmente) milhares de pessoas se passando por um menino. Sim. Ela tinha um fake do Taylor Lautner (e quem viveu sabe, os adolescentes usavam os fakes e sabiam que eram fakes, mas geralmente mentir o próprio gênero era um problemão que acontecia bastante pq fanboy recebia muito mais atenção nas comunidades na época) e se passava por um rapaz. O perfil era tão conhecido que existiam comunidades, milhares de pessoas se dedicando ao fake da Amanda, ela era extremamente conhecida e vivia nas listas na época, e você pode pensar que tudo isso é uma grande coincidência mas, de novo, o perfil da Ana que vive para defender a Dona Alcina das acusações de golpe é encontrado se atrelando a todo esse emaranhado ao responder um tweet ofendendo o Taylor Cent de 2012 em 2020, OITO ANOS DEPOIS. Logo descobriram que o aniversário da AMANDA e do FELIPE é no mesmo dia, poderiam ser gêmeos? Talvez. Em uma ask de anos atrás, o tal Felipe diz ser gêmeo. Talvez ele exista e não tenha relação com nada disso, mas por hora vamos colocar como uma pessoa inexistente pois hoje a dona Alcina apagou TODOS os tweets relacionado ao seu filho. E falando dos filhos, a cadela Serena que faleceu há bastante tempo é também citada no ask.fm do Felipe/Amanda e nesse mesmo ask você encontra ela respondendo que é fã de iCarly e outras coisas, o que também leva a relação de compras feitas no CPF da Alcina recentemente (dvds originais de iCarly), informação encontrada por alguém no twitter.
Quando os perfis no twitter começaram a questionar a história dessa idosa, ela passou a ameaçar as pessoas de que iria denunciá-los a policia, mas ela também tentou justificar muitas coisas. Com o sobrenome dela, foi fácil encontrar parentes. O sobrenome ULM é de pessoas muito poderosas de Salvador na Bahia, onde ela reside. O pai dessa senhora foi Armando Ulm, ex delegado e que foi vereador nos anos 70. A irmã de dona Alcina foi encontrada no facebook e instagram, e ao conversar com o perfil Brinozo, ela afirmou que se ela está utilizando o nome para dar golpes ela (irmã) não sabe de nada. Essa mesma irmã foi detida em 2014 por tráfico de drogas então por isso foi fácil encontra-la, mas outras pessoas da familia também não foram difíceis. Duas pessoas de Salvador com o sobrenome Ulm são donos/sócios de uma empresa que promove eventos como shows e afins na capital, incluindo o famoso Camarote Brahma Salvador. Ontem a Alcina afirmou no twitter que nunca negou que tivesse familia e que o perfil kawoshinudes estava arquitetando todos esses ataques há muito tempo. Passou quase 1h em live falando com uma parede e afirmando que iria abrir um B.O contra o Brinozo e kawoshinudes e supostamente fez isso hoje. Outra coisa interessante é que desde que chamaram a atenção pro fato dos tweets parecerem todos feitos por bot, com curtos períodos (as vezes postados no mesmo minuto) mesmo sendo meio longos pra uma idosa digitar tão rápido, ela parou de postar como fazia e apagou todos os tweets de spam pedindo dinheiro. Além disso, o perfil dela é verificado o que dificulta qualquer denuncia por spam, quem paga o twitter premium pra uma senhora que (segundo ela) quase passa fome? ela diz que uma "boa pessoa" paga pra ajuda-la, pois aparentemente ter selo de verificação é uma das prioridades. O perfil que ela indicou dizendo ser quem pagou o verificado foi desativado. Ela também tem uma legião de perfis de engajamento, além da Ana que já citei, alguns outros com comportamento idêntico vivem para engajar os tweets da idosa e para atacar quem quer que questione a veracidade das histórias dela. Quando no ano passado uma vizinha apareceu no twitter afirmando que a idosa não tem porque pedir dinheiro pois vive bem e tem três imóveis, duas das principais contas atacaram a mulher e aparentemente alguém foi até a casa de uma outra vizinha para pedir esclarecimentos de porque ela estava tentando atacar a Alcina (vocês podem ver neste perfil, clicando pra visualizar as respostas)
Por fim, quero citar novamente que a idosa/amanda se nega a aceitar ajuda que não seja em dinheiro. No ano passado uma pessoa tentou ajudar ela indicando que ela procurasse uma ONG que ajuda mulheres, tanto na DM como em post público, a Alcina não respondeu a DM e apagou o post onde a moça falou sobre a ONG nas respostas. Esse comportamento se repete diversas vezes, uma advogada tentou ajudar ela com a questão da água cortada (ela diz que está há anos sem água encanada) e disse pra ela que não iria cobrar por nada, só queria ajudar. A Alcina BLOQUEOU a mulher. Ela também frequentemente ataca famosos que não a ajudam, mais recentemente foi Felipe Neto e Whindersson Nunes, que ela pediu dinheiro enquanto ambos estavam realizando doações para o RS, ela fez diversos posts criticando e atacando ambos por não doarem dinheiro a ela. Ela também fez durante mais de um ano uma campanha de ataques ao Alok, pois em algum momento de 2020 o DJ disse que sua equipe entraria em contato com ela para ajuda-la e foram-lhe enviados 500 reais em nome do mesmo. Ela achou pouco, acusou ele de engana-la prometendo uma casa, acusou ele de ser o responsável pela campanha dela ficar parada e sem doações. Ela acredita que pessoas famosas DEVEM a ela, e reclama de todo valor que receba de qualquer famoso, seja mil reais ou 500. Nesse momento, depois de tudo começar a tomar um pouco mais de repercussão, ela trancou o perfil então não tive mais acesso aos posts, os últimos que fez foi informando que havia aberto um BO contra usuários do twitter por "atacarem ela" (tava literalmente isso no BO) e também dizendo que a conta do Nubank dela foi bloqueada porque tentaram hackear (o que é muito conveniente uma vez que pessoas que estão nos grupos que ela cria de 'apoiadores' começaram a pedir o extrato da conta).
Enfim, eu não sei se toda essa história se trata de uma mãe e uma filha com sérios problemas psicológicos, ou se uma filha está usando da mãe idosa para aplicar um golpe pela internet, ou talvez ela simplesmente tenha decidido que é confortável viver assim durante tantos anos pois as pessoas vão dar dinheiro pra ela sempre que pedir, só sei que essa história inteira é MUITO estranha. Conheço pessoas que ajudaram há anos e que ainda hoje recebem mensagens dela pedindo por dinheiro, e nesse momento dadas todas as informações e históricos da filha, eu acredito que tudo isso tenha sido um golpe prolongado pq estava dando certo. Tomem cuidado com o que e quem vocês decidem gastar dinheiro e fazer doações na internet, ainda que exista muita gente que precise, existe na mesma medida muita gente aproveitadora. Acho que essa história tá longe de um fim, mas talvez se desenrole em breve caso continue tomando força, lembro que foi numa dessas que desmascararam aquele esquema de golpe utilizando marmitas para moradores de rua.
2024.06.01 01:20 Single-Somewhere2443 Enoxaparin dosing - when to use 1.5 mg/kg SC daily
 | RxPrep book says the treatment dose of VTE (1.5 mg/kg SC daily) is used only for inpatient VTE treatment. This question below (from UWorld), isn't this an inpatient setting? When would we use 1.5 mg/kg? Thanks submitted by Single-Somewhere2443 to NAPLEX_Prep [link] [comments] Also, I'm not sure if I'm overlooking something, but I picked E because UFH wouldn't need renal dose adjustments. I can kinda see why that answer is wrong, UWorld didn't address E, but if you have an explanation I would greatly appreciate it! https://preview.redd.it/44dcjhf8hu3d1.png?width=1226&format=png&auto=webp&s=417f0dff1c0718aa8dcf8895d97ed4d8d43afc67 |
2024.05.31 22:39 AEGISAlliance CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Referral Code: ZULMHXXVCB Solid advice for new plasma donors included! Thank you!
Link to download app:
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
submitted by AEGISAlliance to CSLPlasma [link] [comments]
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
- Plasma is 92% water and the rest is mostly protein elements.
- The plasma is separated from your blood and your red blood cells are returned to you in cycles.
- Per FDA regulations, you're only allowed to donate plasma twice in a 7 day period, with a 48 hour wait inbetween those two times. Don't risk your health by hopping around to different plasma donation centers to circumvent these regulations, and you may get caught if you do.
- Eat a meal high in protein 2-3 hours before donating, but your plasma protein levels depend on what you ate the day before.
- Drink plenty of water and/or non-caffeinated juice before donating to stay hydrated.
- Avoid caffeine such as in coffee or soda before donating or you may get nauseous and vomit or faint during your donation.
- No alcohol 24 hours before, and for a little while after donating.
- No exercising for at least 6 hours after donating as it can put too much stress on the vein.
- Some people get away with smoking or vaping nicotine before and after donating, but it's recommended not to for 2 hours before and after. The nicotine can raise your heart's pulse rate.
- If your pulse rate is 100 or above, you'll be able to do a vitals retake after a 15 minute wait. But if it's 100 or higher again you'll be deferred for the day. If your pulse rate is an issue, listen to "Pink Noise" or "Green Noise" at a low volume before donating which may help reduce your pulse rate, along with its effect on lowering your blood pressure.
- There is a risk of getting a blown vein if the worker is having a hard time finding your vein when they're sticking you with the needle or if you have small veins. You may get deferred until your vein heals if that happens. But it's ok, your body is able to regenerate your veins with a process called Angiogenesis.
- There is a risk of blood clots, but when your blood is constantly moving through the machine it prevents that from happening.
- You may be subject to drug screening. The drug screening tests for methamphetamines, cocaine, and heroin. Certain pharma prescription meds may show up as a false positive so you'll want to let the plasma center know what meds you're taking. Testing positive for these drugs can result in a permanent deferral from donating plasma.
- A sample of your blood will be drawn periodically to test for certain sexually transmitted infections (STIs). A positive test will result in either a temporary or permanent deferral from donating plasma. If you've ever been diagnosed or received treatment for HIV/AIDS, Hepatitis B (HBV) or Hepatitis C (HCV) you will be permanently deferred from donating plasma.
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
- Healthy Feet: Active foot ulcers requiring medical attention will disqualify you from donation.
- Steady Balance: You shouldn't experience dizziness or lightheadedness upon standing.
- Type 1 Consideration: For Type 1 diabetics, eating within two hours of donation is mandatory.
- Wait a few hours before taking the bandage wrap off of your arm after donating.
- It's recommended to use Vitamin E oil/Mineral oil on the needle site for the puncture area to heal better. A Q-tip can be used to apply it easier. I simply dip the Q-Tip in the bottle, but never dip the used cotton back into the bottle.
- Frequently donating over a prolonged period of time may lead to your body having decreased vitamin D levels.
- Red meats are particularly high in the protein vitamins and minerals found in plasma.
- Personally, I take a Now brand Vitamin D supplement that contains vitamin D3, Calcium, Magnesium, and Zinc. But I only take a half a dose, 1 gel capsule instead of 2, since I get these from eating meats and other foods as well. It's bad for your health if you take too much of these vitamins and minerals over time. I also take an Iron supplement. I also drink a protein shake before donating. Just to be safe.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
2024.05.31 22:36 AEGISAlliance CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Referral Code: ZULMHXXVCB Solid advice for new plasma donors included! Thank you!
Link to download app:
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
submitted by AEGISAlliance to CSLPlasmaReferrals [link] [comments]
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
- Plasma is 92% water and the rest is mostly protein elements.
- The plasma is separated from your blood and your red blood cells are returned to you in cycles.
- Per FDA regulations, you're only allowed to donate plasma twice in a 7 day period, with a 48 hour wait inbetween those two times. Don't risk your health by hopping around to different plasma donation centers to circumvent these regulations, and you may get caught if you do.
- Eat a meal high in protein 2-3 hours before donating, but your plasma protein levels depend on what you ate the day before.
- Drink plenty of water and/or non-caffeinated juice before donating to stay hydrated.
- Avoid caffeine such as in coffee or soda before donating or you may get nauseous and vomit or faint during your donation.
- No alcohol 24 hours before, and for a little while after donating.
- No exercising for at least 6 hours after donating as it can put too much stress on the vein.
- Some people get away with smoking or vaping nicotine before and after donating, but it's recommended not to for 2 hours before and after. The nicotine can raise your heart's pulse rate.
- If your pulse rate is 100 or above, you'll be able to do a vitals retake after a 15 minute wait. But if it's 100 or higher again you'll be deferred for the day. If your pulse rate is an issue, listen to "Pink Noise" or "Green Noise" at a low volume before donating which may help reduce your pulse rate, along with its effect on lowering your blood pressure.
- There is a risk of getting a blown vein if the worker is having a hard time finding your vein when they're sticking you with the needle or if you have small veins. You may get deferred until your vein heals if that happens. But it's ok, your body is able to regenerate your veins with a process called Angiogenesis.
- There is a risk of blood clots, but when your blood is constantly moving through the machine it prevents that from happening.
- You may be subject to drug screening. The drug screening tests for methamphetamines, cocaine, and heroin. Certain pharma prescription meds may show up as a false positive so you'll want to let the plasma center know what meds you're taking. Testing positive for these drugs can result in a permanent deferral from donating plasma.
- A sample of your blood will be drawn periodically to test for certain sexually transmitted infections (STIs). A positive test will result in either a temporary or permanent deferral from donating plasma. If you've ever been diagnosed or received treatment for HIV/AIDS, Hepatitis B (HBV) or Hepatitis C (HCV) you will be permanently deferred from donating plasma.
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
- Healthy Feet: Active foot ulcers requiring medical attention will disqualify you from donation.
- Steady Balance: You shouldn't experience dizziness or lightheadedness upon standing.
- Type 1 Consideration: For Type 1 diabetics, eating within two hours of donation is mandatory.
- Wait a few hours before taking the bandage wrap off of your arm after donating.
- It's recommended to use Vitamin E oil/Mineral oil on the needle site for the puncture area to heal better. A Q-tip can be used to apply it easier. I simply dip the Q-Tip in the bottle, but never dip the used cotton back into the bottle.
- Frequently donating over a prolonged period of time may lead to your body having decreased vitamin D levels.
- Red meats are particularly high in the protein vitamins and minerals found in plasma.
- Personally, I take a Now brand Vitamin D supplement that contains vitamin D3, Calcium, Magnesium, and Zinc. But I only take a half a dose, 1 gel capsule instead of 2, since I get these from eating meats and other foods as well. It's bad for your health if you take too much of these vitamins and minerals over time. I also take an Iron supplement. I also drink a protein shake before donating. Just to be safe.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
2024.05.31 20:44 BigMagnut Can mitochondrial specific training reverse metabolic syndrome?
Zone 2 training, which involves exercising at a moderate intensity (typically 60-70% of maximum heart rate), can reverse metabolic syndrome through several detailed mechanisms. This form of exercise enhances the body's ability to oxidize fat as a primary fuel source, thereby improving metabolic flexibility. By operating predominantly within the aerobic energy system, Zone 2 training increases the efficiency and capacity of mitochondria, the powerhouses of cells, thereby enhancing overall energy metabolism. The increased mitochondrial density and function allow for better utilization of glucose and fatty acids, reducing blood glucose levels and improving insulin sensitivity, which are crucial factors in reversing metabolic syndrome.
One significant benefit of Zone 2 training is the improvement in insulin sensitivity. Exercise at this intensity enhances the muscles' ability to uptake glucose, independent of insulin, through increased translocation of glucose transporter type 4 (GLUT4) to the cell surface. This effect not only helps in lowering blood glucose levels but also decreases insulin resistance, a key component of metabolic syndrome. Improved insulin sensitivity means that the body requires less insulin to manage blood sugar levels, alleviating the burden on pancreatic beta cells and reducing the risk of developing type 2 diabetes (BMJ Open Access) (BioMed Central).
Another crucial mechanism is the reduction of visceral fat, which is closely associated with metabolic syndrome. Zone 2 training promotes lipolysis, the breakdown of fats, and enhances fat oxidation, leading to a decrease in visceral adiposity. Reduced visceral fat decreases the production of pro-inflammatory cytokines and adipokines that contribute to chronic inflammation and insulin resistance. Consequently, lowering visceral fat not only helps in managing weight but also mitigates the inflammatory state that exacerbates metabolic syndrome (Diabetes Journals).
Furthermore, Zone 2 training improves cardiovascular health by lowering blood pressure, enhancing endothelial function, and increasing HDL cholesterol levels while reducing LDL cholesterol and triglycerides. These cardiovascular benefits reduce the risk of atherosclerosis and other cardiovascular diseases, which are often comorbid with metabolic syndrome. By improving vascular function and lipid profiles, Zone 2 training addresses several risk factors associated with metabolic syndrome, leading to a comprehensive improvement in metabolic health (Diabetes Journals).
Overall, Zone 2 training offers a multifaceted approach to reversing metabolic syndrome by enhancing mitochondrial function, improving insulin sensitivity, reducing visceral fat, and promoting cardiovascular health. These combined effects lead to a substantial improvement in metabolic health and a reduction in the risk factors associated with metabolic syndrome.
Resistance training has a significant impact on reversing metabolic syndrome through multiple mechanisms, enhancing overall metabolic health. Engaging in regular resistance exercise leads to increased muscle mass and strength, which is crucial for improving metabolic rate. A higher metabolic rate helps in better energy expenditure and fat oxidation, reducing body fat and visceral adiposity, both of which are key factors in metabolic syndrome.
One of the primary ways resistance training helps is by improving insulin sensitivity. Muscle contractions during resistance exercises stimulate glucose uptake into the muscles independently of insulin. This increased glucose uptake helps lower blood glucose levels and reduces insulin resistance, a core component of metabolic syndrome. Studies have shown that resistance training can significantly reduce hemoglobin A1c levels, a marker of long-term blood glucose control, thereby improving glycemic control (BioMed Central).
Resistance training also positively affects lipid profiles, which are often dysregulated in metabolic syndrome. It helps lower LDL cholesterol and triglycerides while increasing HDL cholesterol levels. These changes contribute to a better cardiovascular risk profile, reducing the risk of atherosclerosis and other cardiovascular diseases commonly associated with metabolic syndrome (Diabetes Journals). Additionally, the reduction in visceral fat due to resistance training decreases the production of pro-inflammatory cytokines, further mitigating the inflammatory state associated with metabolic syndrome.
Moreover, resistance training improves cardiovascular health by reducing resting blood pressure and enhancing endothelial function. This is crucial because hypertension is a common component of metabolic syndrome. Improved muscle strength and endurance from resistance training also contribute to overall physical function and quality of life, making it easier to maintain an active lifestyle, which is essential for long-term metabolic health (Diabetes Journals) (Oxford Academic).
Intermittent hypoxia (IH) involves short periods of low oxygen followed by normal levels. Studies show IH enhances mitochondrial biogenesis, crucial for cellular energy and metabolic health.
Research indicates IH increases mitochondrial DNA, biogenesis markers, and oxidative enzyme activity. In J Physiol, healthy adults showed significant mitochondrial improvements with IH. In Diabetes, obese individuals improved insulin sensitivity and mitochondrial function through IH.
IH appears effective for managing metabolic syndrome by enhancing mitochondrial function and metabolic health. Further research with larger samples and longer follow-ups is needed to confirm its long-term efficacy and safety.
HIIT significantly enhances mitochondrial biogenesis by creating high energy demands and producing reactive oxygen species (ROS), which act as signaling molecules for adaptive responses. During intense exercise bursts, localized hypoxia occurs in the muscles, stabilizing hypoxia-inducible factors (HIFs) that activate genes promoting mitochondrial biogenesis and improved oxygen utilization.
Intermittent hypoxia (IH) within HIIT plays a crucial role in these adaptations. The temporary hypoxic conditions during HIIT sessions induce similar responses to IH protocols, enhancing mitochondrial function and metabolic health. Thus, HIIT effectively boosts mitochondrial biogenesis through increased energy demands, ROS production, and HIF activation due to localized hypoxia.
To sustain the benefits of endurance training and boost mitochondrial function, several supplements and drugs are supported by varying degrees of scientific consensus.
Coenzyme Q10 (CoQ10) is well-supported by research for its role in enhancing mitochondrial ATP production and reducing fatigue. Numerous studies have shown CoQ10's effectiveness in improving exercise performance and overall mitochondrial health (BMJ Open Access) (Diabetes Journals).
Acetyl-L-Carnitine (ALCAR) is also widely researched and known for transporting fatty acids into mitochondria for energy production, thus reducing oxidative damage and improving mitochondrial function and endurance (BioMed Central) (Diabetes Journals).
Alpha-Lipoic Acid (ALA) acts as an antioxidant and has been shown to improve insulin sensitivity and mitochondrial function, making it a beneficial supplement for maintaining the effects of endurance training (BMJ Open Access) (Diabetes Journals).
Nicotinamide Riboside (NR) has a growing body of evidence supporting its role as a precursor to NAD+, a crucial coenzyme for mitochondrial function and energy metabolism. Research indicates that NR supplementation improves mitochondrial function and supports healthy aging (BioMed Central) (Diabetes Journals).
PQQ (Pyrroloquinoline Quinone) promotes mitochondrial biogenesis and has shown promise in enhancing cognitive function and energy metabolism. While the research is positive, it is less extensive compared to CoQ10 and ALCAR (BioMed Central) (Diabetes Journals).
Urolithin A (Mitopure) stimulates mitochondrial biogenesis and has demonstrated benefits in clinical trials, including improved muscle function and endurance. The research is promising but still emerging (BioMed Central) (Diabetes Journals).
Metformin, primarily used for diabetes management, activates AMPK and enhances mitochondrial biogenesis and insulin sensitivity. It has been shown to have positive effects on mitochondrial function, though it is primarily prescribed for its glucose-lowering effects (Diabetes Journals).
Rapamycin inhibits the mTOR pathway, enhancing mitochondrial function and potentially extending lifespan. Its use is more experimental and comes with potential side effects, making it less commonly recommended solely for mitochondrial health (Diabetes Journals).
CoQ10 and ALCAR are the most extensively supported by research, followed by ALA and NR. PQQ and Urolithin A have emerging support, while metformin and rapamycin are more specialized with broader implications for their use. Always consult a healthcare professional before starting any new supplement or medication.
Thoughts on Complex 1 inhibitors Some of these supplements are very speculative. Peter Attia is not convinced of NAD and neither am I. It might have an impact, but it's not been studied long term. Peter Attia also is not convinced of the utility of Metformin and neither am I. In my experience with Metformin and Berberine, while my fitness improved on some levels, my lactate levels were higher, it seemed to put me into a carb rather than fat burning mode of operations. Basically the same result Peter Attia experienced is what I experienced. As a result of this, it's a bad idea to use Metformin or Berberine.
Metformin blunts some benefits of exercise due to its activation of AMP-activated protein kinase (AMPK), a key energy regulator that both metformin and exercise activate. When both are active simultaneously, the overlapping pathways can reduce the exercise-induced improvements in insulin sensitivity and mitochondrial adaptations. This overlap leads to a state where the additive effects of exercise on these pathways are diminished, as the body is already experiencing heightened AMPK activation due to metformin (BMJ Open Access) (Diabetes Journals).
Additionally, metformin interferes with mitochondrial biogenesis, a process that exercise naturally promotes to enhance cellular energy capacity. While metformin improves mitochondrial function in insulin-resistant tissues, it may hinder the exercise-induced mitochondrial adaptations in healthy tissues. This interference results in less pronounced improvements in muscle oxidative capacity and endurance performance during physical activities (Diabetes Journals) (Diabetes Journals).
The increase in lactate levels observed with metformin use is primarily due to its inhibition of complex 1 in the mitochondrial electron transport chain, which shifts energy production from oxidative phosphorylation to anaerobic glycolysis. This shift increases lactate production as a byproduct of glycolysis. Furthermore, metformin disrupts the lactate shuttle, which involves the transport of lactate to the liver for gluconeogenesis, thus accumulating lactate in the blood. These mechanisms collectively contribute to elevated lactate levels during exercise in individuals taking metformin (Diabetes Journals) (Diabetes Journals).
There are additional supplements I've tried like bergamot, but I'm not sure if this particular supplement helped or hurt. If I had to guess, it seems to have a mix between statin like effects and metformin like effects. It works by an entirely different mechanism from Metformin or berberine. Berberine itself works by a different mechanism from Metformin, but because it is a confirmed complex 1 inhibitor it's just as bad. The main difference is berberine has a very short half life while metformin has an unusually long half life. By inhibiting complex I, berberine reduces ATP production through oxidative phosphorylation and increases the reliance on glycolysis for energy production. This inhibition leads to a mild increase in the production of reactive oxygen species (ROS), which can have various signaling effects on cellular metabolism (BMJ Open Access) (Diabetes Journals).
Lactate Shuttle Hypothesis, proposed by George Brooks in the 1980s, redefines lactate's role in metabolism. Traditionally viewed as a mere byproduct of anaerobic metabolism, lactate is now recognized as a crucial intermediary in energy production and metabolic regulation. During glycolysis, lactate is produced from pyruvate, especially under anaerobic conditions. This hypothesis posits that lactate is not just an end-product but a vital fuel source, transportable and oxidizable by various tissues, including the heart, brain, and skeletal muscles.
Lactate produced in one cell can be transported to another cell or tissue via monocarboxylate transporters (MCTs). This transport allows lactate to be converted back into pyruvate, which can then enter mitochondria for oxidation, contributing to ATP production during aerobic metabolism. This mechanism facilitates energy redistribution within and between tissues. For example, during intense exercise, lactate produced by fast-twitch muscle fibers can be transported to slow-twitch fibers for oxidation, optimizing energy utilization. The lactate shuttle thus supports the coordination of energy supply and demand across different organs and tissues, enhancing overall metabolic efficiency.
Numerous studies have confirmed the presence and function of MCTs in lactate transport and utilization. Research has shown that lactate can be taken up and oxidized by muscle cells' mitochondria and other tissues, providing a significant energy source during and after exercise. This concept has significant implications for understanding metabolic diseases and exercise physiology. It suggests that improving lactate clearance and utilization could benefit conditions like heart failure and diabetes, where metabolic flexibility is compromised. Understanding the lactate shuttle helps clarify the complex interplay of metabolic processes during exercise and in metabolic disorders, highlighting lactate's central role in energy metabolism.
Urolithin A is a metabolite derived from ellagitannins, compounds found in fruits like pomegranates, berries, and nuts. It is known for its potential benefits on mitochondrial health and muscle function. Urolithin A promotes mitophagy, a selective degradation process that removes damaged mitochondria, ensuring the maintenance and regeneration of healthy ones. This process is vital for maintaining mitochondrial quality, particularly in metabolically active tissues like muscle.
Urolithin A enhances mitophagy by activating the PINK1-Parkin pathway, which tags damaged mitochondria for degradation, promoting overall mitochondrial health and function. Additionally, by removing defective mitochondria, Urolithin A supports mitochondrial biogenesis, increasing the number and efficiency of mitochondria, which boosts cellular energy production and metabolic efficiency. It also exhibits anti-inflammatory properties, reducing chronic inflammation that can impair mitochondrial function and contribute to metabolic disorders.
Studies have shown the benefits of Urolithin A on mitochondrial health and muscle function. Preclinical studies indicate that Urolithin A extends lifespan and improves muscle function in animal models by enhancing mitophagy and mitochondrial biogenesis. Human clinical trials, such as one published in Nature Metabolism, have shown that Urolithin A supplementation can improve muscle endurance and mitochondrial health in older adults, suggesting its potential for mitigating age-related decline in muscle and metabolic health.
Integrating Urolithin A into a training program can enhance the benefits of exercise by improving mitochondrial function and muscle health. Urolithin A can be taken as a dietary supplement in the form of capsules or powder, ideally alongside meals for better absorption. Consistency is key, so it should be a part of the daily routine. Combining Urolithin A with regular exercise, particularly endurance and resistance training, can maximize its benefits since exercise itself promotes mitochondrial biogenesis and function. Monitoring improvements in muscle strength, endurance, and overall metabolic health can help assess the effectiveness of Urolithin A as part of a training regimen.
My experience with Urolithin A (mitopure) so far has been positive. This supplement seems to have a positive effect on mitochondria whether you exercise or not. When combined with exercise it seems to have only positive effects. This is in contrast to the complex 1 inhibitors or even certain statins which seem to have some sort of negative or blunting effect on the adaptations. Statins at least for now are necessary until better drugs become widely available and cheap, but metformin or berberine may be unnecessary for people who are willing to go the exercise route.
The PINK1-Parkin Pathway and Its Role in Mitophagy
Urolithin A activates the PINK1-Parkin pathway, a crucial mechanism for maintaining mitochondrial health through the process of mitophagy. Mitophagy is the selective degradation of damaged or dysfunctional mitochondria by autophagy, ensuring that cells maintain a healthy and functional mitochondrial population. Understanding how Urolithin A activates this pathway helps clarify its beneficial effects on mitochondrial health.
By activating the PINK1-Parkin pathway, Urolithin A helps maintain a healthy mitochondrial population, which is essential for optimal cellular energy production and metabolic health. This mechanism underscores its potential benefits for improving exercise performance and reversing metabolic disorders.
The problem with lifestyle measures is the endurance training benefits don't last long. It's not a cure for metabolic syndrome but it's more like an effective treatment. It can mitigate some of the risks. Insulin resistance for example might not be as bad if you spend a lot of time doing resistance training and Zone 2/Zone 5 cardio. The lifestyle measure seems to work better than metformin but only if you can do it consistently for years. The muscle you build will allow for more carbs to be consumed, and for more glucose to be stored in the muscles instead of the liver. Fatty liver disease and visceral fat are problems, and lifestyle can avoid these problems better than any drug so far. Genetic factors cannot be controlled for, and some new drugs may have to be created for people who are genetically highly likely to develop type 2 diabetes, or who have high cholesterol for no dietary reasons. PCSK9 inhibitors are an example of this and maybe alphaGO will be able to help find new targets or pathways for drugs to improve mitochondria function.
submitted by BigMagnut to PeterAttia [link] [comments]
One significant benefit of Zone 2 training is the improvement in insulin sensitivity. Exercise at this intensity enhances the muscles' ability to uptake glucose, independent of insulin, through increased translocation of glucose transporter type 4 (GLUT4) to the cell surface. This effect not only helps in lowering blood glucose levels but also decreases insulin resistance, a key component of metabolic syndrome. Improved insulin sensitivity means that the body requires less insulin to manage blood sugar levels, alleviating the burden on pancreatic beta cells and reducing the risk of developing type 2 diabetes (BMJ Open Access) (BioMed Central).
Another crucial mechanism is the reduction of visceral fat, which is closely associated with metabolic syndrome. Zone 2 training promotes lipolysis, the breakdown of fats, and enhances fat oxidation, leading to a decrease in visceral adiposity. Reduced visceral fat decreases the production of pro-inflammatory cytokines and adipokines that contribute to chronic inflammation and insulin resistance. Consequently, lowering visceral fat not only helps in managing weight but also mitigates the inflammatory state that exacerbates metabolic syndrome (Diabetes Journals).
Furthermore, Zone 2 training improves cardiovascular health by lowering blood pressure, enhancing endothelial function, and increasing HDL cholesterol levels while reducing LDL cholesterol and triglycerides. These cardiovascular benefits reduce the risk of atherosclerosis and other cardiovascular diseases, which are often comorbid with metabolic syndrome. By improving vascular function and lipid profiles, Zone 2 training addresses several risk factors associated with metabolic syndrome, leading to a comprehensive improvement in metabolic health (Diabetes Journals).
Overall, Zone 2 training offers a multifaceted approach to reversing metabolic syndrome by enhancing mitochondrial function, improving insulin sensitivity, reducing visceral fat, and promoting cardiovascular health. These combined effects lead to a substantial improvement in metabolic health and a reduction in the risk factors associated with metabolic syndrome.
Resistance training has a significant impact on reversing metabolic syndrome through multiple mechanisms, enhancing overall metabolic health. Engaging in regular resistance exercise leads to increased muscle mass and strength, which is crucial for improving metabolic rate. A higher metabolic rate helps in better energy expenditure and fat oxidation, reducing body fat and visceral adiposity, both of which are key factors in metabolic syndrome.
One of the primary ways resistance training helps is by improving insulin sensitivity. Muscle contractions during resistance exercises stimulate glucose uptake into the muscles independently of insulin. This increased glucose uptake helps lower blood glucose levels and reduces insulin resistance, a core component of metabolic syndrome. Studies have shown that resistance training can significantly reduce hemoglobin A1c levels, a marker of long-term blood glucose control, thereby improving glycemic control (BioMed Central).
Resistance training also positively affects lipid profiles, which are often dysregulated in metabolic syndrome. It helps lower LDL cholesterol and triglycerides while increasing HDL cholesterol levels. These changes contribute to a better cardiovascular risk profile, reducing the risk of atherosclerosis and other cardiovascular diseases commonly associated with metabolic syndrome (Diabetes Journals). Additionally, the reduction in visceral fat due to resistance training decreases the production of pro-inflammatory cytokines, further mitigating the inflammatory state associated with metabolic syndrome.
Moreover, resistance training improves cardiovascular health by reducing resting blood pressure and enhancing endothelial function. This is crucial because hypertension is a common component of metabolic syndrome. Improved muscle strength and endurance from resistance training also contribute to overall physical function and quality of life, making it easier to maintain an active lifestyle, which is essential for long-term metabolic health (Diabetes Journals) (Oxford Academic).
Intermittent hypoxia (IH) involves short periods of low oxygen followed by normal levels. Studies show IH enhances mitochondrial biogenesis, crucial for cellular energy and metabolic health.
Research indicates IH increases mitochondrial DNA, biogenesis markers, and oxidative enzyme activity. In J Physiol, healthy adults showed significant mitochondrial improvements with IH. In Diabetes, obese individuals improved insulin sensitivity and mitochondrial function through IH.
IH appears effective for managing metabolic syndrome by enhancing mitochondrial function and metabolic health. Further research with larger samples and longer follow-ups is needed to confirm its long-term efficacy and safety.
HIIT significantly enhances mitochondrial biogenesis by creating high energy demands and producing reactive oxygen species (ROS), which act as signaling molecules for adaptive responses. During intense exercise bursts, localized hypoxia occurs in the muscles, stabilizing hypoxia-inducible factors (HIFs) that activate genes promoting mitochondrial biogenesis and improved oxygen utilization.
Intermittent hypoxia (IH) within HIIT plays a crucial role in these adaptations. The temporary hypoxic conditions during HIIT sessions induce similar responses to IH protocols, enhancing mitochondrial function and metabolic health. Thus, HIIT effectively boosts mitochondrial biogenesis through increased energy demands, ROS production, and HIF activation due to localized hypoxia.
To sustain the benefits of endurance training and boost mitochondrial function, several supplements and drugs are supported by varying degrees of scientific consensus.
Coenzyme Q10 (CoQ10) is well-supported by research for its role in enhancing mitochondrial ATP production and reducing fatigue. Numerous studies have shown CoQ10's effectiveness in improving exercise performance and overall mitochondrial health (BMJ Open Access) (Diabetes Journals).
Acetyl-L-Carnitine (ALCAR) is also widely researched and known for transporting fatty acids into mitochondria for energy production, thus reducing oxidative damage and improving mitochondrial function and endurance (BioMed Central) (Diabetes Journals).
Alpha-Lipoic Acid (ALA) acts as an antioxidant and has been shown to improve insulin sensitivity and mitochondrial function, making it a beneficial supplement for maintaining the effects of endurance training (BMJ Open Access) (Diabetes Journals).
Nicotinamide Riboside (NR) has a growing body of evidence supporting its role as a precursor to NAD+, a crucial coenzyme for mitochondrial function and energy metabolism. Research indicates that NR supplementation improves mitochondrial function and supports healthy aging (BioMed Central) (Diabetes Journals).
PQQ (Pyrroloquinoline Quinone) promotes mitochondrial biogenesis and has shown promise in enhancing cognitive function and energy metabolism. While the research is positive, it is less extensive compared to CoQ10 and ALCAR (BioMed Central) (Diabetes Journals).
Urolithin A (Mitopure) stimulates mitochondrial biogenesis and has demonstrated benefits in clinical trials, including improved muscle function and endurance. The research is promising but still emerging (BioMed Central) (Diabetes Journals).
Metformin, primarily used for diabetes management, activates AMPK and enhances mitochondrial biogenesis and insulin sensitivity. It has been shown to have positive effects on mitochondrial function, though it is primarily prescribed for its glucose-lowering effects (Diabetes Journals).
Rapamycin inhibits the mTOR pathway, enhancing mitochondrial function and potentially extending lifespan. Its use is more experimental and comes with potential side effects, making it less commonly recommended solely for mitochondrial health (Diabetes Journals).
CoQ10 and ALCAR are the most extensively supported by research, followed by ALA and NR. PQQ and Urolithin A have emerging support, while metformin and rapamycin are more specialized with broader implications for their use. Always consult a healthcare professional before starting any new supplement or medication.
Thoughts on Complex 1 inhibitors Some of these supplements are very speculative. Peter Attia is not convinced of NAD and neither am I. It might have an impact, but it's not been studied long term. Peter Attia also is not convinced of the utility of Metformin and neither am I. In my experience with Metformin and Berberine, while my fitness improved on some levels, my lactate levels were higher, it seemed to put me into a carb rather than fat burning mode of operations. Basically the same result Peter Attia experienced is what I experienced. As a result of this, it's a bad idea to use Metformin or Berberine.
Metformin blunts some benefits of exercise due to its activation of AMP-activated protein kinase (AMPK), a key energy regulator that both metformin and exercise activate. When both are active simultaneously, the overlapping pathways can reduce the exercise-induced improvements in insulin sensitivity and mitochondrial adaptations. This overlap leads to a state where the additive effects of exercise on these pathways are diminished, as the body is already experiencing heightened AMPK activation due to metformin (BMJ Open Access) (Diabetes Journals).
Additionally, metformin interferes with mitochondrial biogenesis, a process that exercise naturally promotes to enhance cellular energy capacity. While metformin improves mitochondrial function in insulin-resistant tissues, it may hinder the exercise-induced mitochondrial adaptations in healthy tissues. This interference results in less pronounced improvements in muscle oxidative capacity and endurance performance during physical activities (Diabetes Journals) (Diabetes Journals).
The increase in lactate levels observed with metformin use is primarily due to its inhibition of complex 1 in the mitochondrial electron transport chain, which shifts energy production from oxidative phosphorylation to anaerobic glycolysis. This shift increases lactate production as a byproduct of glycolysis. Furthermore, metformin disrupts the lactate shuttle, which involves the transport of lactate to the liver for gluconeogenesis, thus accumulating lactate in the blood. These mechanisms collectively contribute to elevated lactate levels during exercise in individuals taking metformin (Diabetes Journals) (Diabetes Journals).
There are additional supplements I've tried like bergamot, but I'm not sure if this particular supplement helped or hurt. If I had to guess, it seems to have a mix between statin like effects and metformin like effects. It works by an entirely different mechanism from Metformin or berberine. Berberine itself works by a different mechanism from Metformin, but because it is a confirmed complex 1 inhibitor it's just as bad. The main difference is berberine has a very short half life while metformin has an unusually long half life. By inhibiting complex I, berberine reduces ATP production through oxidative phosphorylation and increases the reliance on glycolysis for energy production. This inhibition leads to a mild increase in the production of reactive oxygen species (ROS), which can have various signaling effects on cellular metabolism (BMJ Open Access) (Diabetes Journals).
Lactate Shuttle Hypothesis, proposed by George Brooks in the 1980s, redefines lactate's role in metabolism. Traditionally viewed as a mere byproduct of anaerobic metabolism, lactate is now recognized as a crucial intermediary in energy production and metabolic regulation. During glycolysis, lactate is produced from pyruvate, especially under anaerobic conditions. This hypothesis posits that lactate is not just an end-product but a vital fuel source, transportable and oxidizable by various tissues, including the heart, brain, and skeletal muscles.
Lactate produced in one cell can be transported to another cell or tissue via monocarboxylate transporters (MCTs). This transport allows lactate to be converted back into pyruvate, which can then enter mitochondria for oxidation, contributing to ATP production during aerobic metabolism. This mechanism facilitates energy redistribution within and between tissues. For example, during intense exercise, lactate produced by fast-twitch muscle fibers can be transported to slow-twitch fibers for oxidation, optimizing energy utilization. The lactate shuttle thus supports the coordination of energy supply and demand across different organs and tissues, enhancing overall metabolic efficiency.
Numerous studies have confirmed the presence and function of MCTs in lactate transport and utilization. Research has shown that lactate can be taken up and oxidized by muscle cells' mitochondria and other tissues, providing a significant energy source during and after exercise. This concept has significant implications for understanding metabolic diseases and exercise physiology. It suggests that improving lactate clearance and utilization could benefit conditions like heart failure and diabetes, where metabolic flexibility is compromised. Understanding the lactate shuttle helps clarify the complex interplay of metabolic processes during exercise and in metabolic disorders, highlighting lactate's central role in energy metabolism.
Urolithin A is a metabolite derived from ellagitannins, compounds found in fruits like pomegranates, berries, and nuts. It is known for its potential benefits on mitochondrial health and muscle function. Urolithin A promotes mitophagy, a selective degradation process that removes damaged mitochondria, ensuring the maintenance and regeneration of healthy ones. This process is vital for maintaining mitochondrial quality, particularly in metabolically active tissues like muscle.
Urolithin A enhances mitophagy by activating the PINK1-Parkin pathway, which tags damaged mitochondria for degradation, promoting overall mitochondrial health and function. Additionally, by removing defective mitochondria, Urolithin A supports mitochondrial biogenesis, increasing the number and efficiency of mitochondria, which boosts cellular energy production and metabolic efficiency. It also exhibits anti-inflammatory properties, reducing chronic inflammation that can impair mitochondrial function and contribute to metabolic disorders.
Studies have shown the benefits of Urolithin A on mitochondrial health and muscle function. Preclinical studies indicate that Urolithin A extends lifespan and improves muscle function in animal models by enhancing mitophagy and mitochondrial biogenesis. Human clinical trials, such as one published in Nature Metabolism, have shown that Urolithin A supplementation can improve muscle endurance and mitochondrial health in older adults, suggesting its potential for mitigating age-related decline in muscle and metabolic health.
Integrating Urolithin A into a training program can enhance the benefits of exercise by improving mitochondrial function and muscle health. Urolithin A can be taken as a dietary supplement in the form of capsules or powder, ideally alongside meals for better absorption. Consistency is key, so it should be a part of the daily routine. Combining Urolithin A with regular exercise, particularly endurance and resistance training, can maximize its benefits since exercise itself promotes mitochondrial biogenesis and function. Monitoring improvements in muscle strength, endurance, and overall metabolic health can help assess the effectiveness of Urolithin A as part of a training regimen.
My experience with Urolithin A (mitopure) so far has been positive. This supplement seems to have a positive effect on mitochondria whether you exercise or not. When combined with exercise it seems to have only positive effects. This is in contrast to the complex 1 inhibitors or even certain statins which seem to have some sort of negative or blunting effect on the adaptations. Statins at least for now are necessary until better drugs become widely available and cheap, but metformin or berberine may be unnecessary for people who are willing to go the exercise route.
The PINK1-Parkin Pathway and Its Role in Mitophagy
Urolithin A activates the PINK1-Parkin pathway, a crucial mechanism for maintaining mitochondrial health through the process of mitophagy. Mitophagy is the selective degradation of damaged or dysfunctional mitochondria by autophagy, ensuring that cells maintain a healthy and functional mitochondrial population. Understanding how Urolithin A activates this pathway helps clarify its beneficial effects on mitochondrial health.
The PINK1-Parkin Pathway
PINK1 (PTEN-induced kinase 1) and Parkin are two key proteins involved in the identification and removal of damaged mitochondria:- PINK1:
- PINK1 is a serine/threonine-protein kinase that is normally imported into healthy mitochondria and rapidly degraded.
- When mitochondria become damaged (e.g., due to loss of membrane potential), PINK1 accumulates on the outer mitochondrial membrane instead of being imported and degraded.
- The accumulation of PINK1 on the outer membrane serves as a signal indicating mitochondrial damage.
- Parkin:
- Parkin is an E3 ubiquitin ligase that is recruited to the outer mitochondrial membrane by PINK1.
- Upon recruitment, Parkin ubiquitinates various outer mitochondrial membrane proteins, tagging the damaged mitochondria for degradation.
Mechanism of Action
When mitochondria are healthy, PINK1 is continuously imported into the mitochondria and degraded. However, in the presence of damaged mitochondria with decreased membrane potential, PINK1 accumulates on the outer membrane. This accumulation acts as a signal to recruit and activate Parkin. Activated Parkin ubiquitinates specific proteins on the outer mitochondrial membrane, marking the damaged mitochondria for degradation by the autophagy machinery. This process involves the formation of autophagosomes around the damaged mitochondria, which are then delivered to lysosomes for degradation and recycling.Urolithin A and the PINK1-Parkin Pathway
Urolithin A enhances mitophagy by modulating the PINK1-Parkin pathway. It promotes the accumulation of PINK1 on damaged mitochondria, leading to the recruitment and activation of Parkin. This activation results in increased ubiquitination of mitochondrial proteins and subsequent autophagic degradation of damaged mitochondria. By facilitating this process, Urolithin A ensures the removal of dysfunctional mitochondria, promoting the regeneration of healthy ones.Supporting Studies
Research has shown that Urolithin A can activate the PINK1-Parkin pathway and enhance mitophagy in various models:- A study published in Nature Metabolism demonstrated that Urolithin A improved mitochondrial health and muscle function in older adults by activating mitophagy through the PINK1-Parkin pathway (BMJ Open Access) (BioMed Central).
- Another study in Cell Reports showed that Urolithin A induced mitophagy and improved mitochondrial function in aging muscle, supporting the idea that this compound can help mitigate age-related decline in mitochondrial health (Diabetes Journals).
Implementation in a Training Program
To implement Urolithin A in a training program, it can be taken as a dietary supplement alongside regular exercise. Consistency in supplementation and exercise is key, as both activities synergistically promote mitochondrial health. Monitoring progress in muscle strength, endurance, and overall metabolic health can help assess the effectiveness of this approach.By activating the PINK1-Parkin pathway, Urolithin A helps maintain a healthy mitochondrial population, which is essential for optimal cellular energy production and metabolic health. This mechanism underscores its potential benefits for improving exercise performance and reversing metabolic disorders.
The problem with lifestyle measures is the endurance training benefits don't last long. It's not a cure for metabolic syndrome but it's more like an effective treatment. It can mitigate some of the risks. Insulin resistance for example might not be as bad if you spend a lot of time doing resistance training and Zone 2/Zone 5 cardio. The lifestyle measure seems to work better than metformin but only if you can do it consistently for years. The muscle you build will allow for more carbs to be consumed, and for more glucose to be stored in the muscles instead of the liver. Fatty liver disease and visceral fat are problems, and lifestyle can avoid these problems better than any drug so far. Genetic factors cannot be controlled for, and some new drugs may have to be created for people who are genetically highly likely to develop type 2 diabetes, or who have high cholesterol for no dietary reasons. PCSK9 inhibitors are an example of this and maybe alphaGO will be able to help find new targets or pathways for drugs to improve mitochondria function.
2024.05.31 19:15 ExProEx I need a pep talk please
I'm I Dietetics student, super senior. I started the program because I needed to shift careers from food service, which I had done for 20 years, and my career had stalled due to my (lack of 24/7) availability, as my husband is disabled and my son's autistic. My husband had just been diagnosed with celiac disease, and finally things were falling into place for his health. I saw how much difference diet really makes.
This spring, my husband's kidneys failed, he's now on dialysis and the transplant list. A month later, my son was diagnosed with type 1 diabetes and AKI, he also had elevated IgE antibodies, so we're waiting on an immunology appointment. A month and a half later, I had a gallbladder attack and am now waiting for surgery, my kidneys may also have taken damage, have to wait and see on that.
Every time, I come home, I dive into the MNT book, I figure out a plan and a shopping list. I'm starting to feel like I'm only ever going to use this degree for family members. I can only go part time because of my family's needs, and unless my husband gets a kidney suspiciously fast, I'm going to have to finish my master's (also part time) before doing my internship. Which, how am I even going to be away from home 40 hours a week?
I know this is what I want to do, I'm just losing hope that I'll ever actually get to do it.
submitted by ExProEx to dietetics [link] [comments]
This spring, my husband's kidneys failed, he's now on dialysis and the transplant list. A month later, my son was diagnosed with type 1 diabetes and AKI, he also had elevated IgE antibodies, so we're waiting on an immunology appointment. A month and a half later, I had a gallbladder attack and am now waiting for surgery, my kidneys may also have taken damage, have to wait and see on that.
Every time, I come home, I dive into the MNT book, I figure out a plan and a shopping list. I'm starting to feel like I'm only ever going to use this degree for family members. I can only go part time because of my family's needs, and unless my husband gets a kidney suspiciously fast, I'm going to have to finish my master's (also part time) before doing my internship. Which, how am I even going to be away from home 40 hours a week?
I know this is what I want to do, I'm just losing hope that I'll ever actually get to do it.
2024.05.31 11:51 ConfidentTaste1038 Phd Thesis Assistance Services
 | submitted by ConfidentTaste1038 to Thesis_Writing_Vikas [link] [comments] |
2024.05.31 08:56 Longjumping_Fly_2978 Sono diabetico di tipo 2 con emoglobina glicata molto alta : un medico endocrinologo che si rifiuta di prescrivermi l'insulina e vuole darmi a tutti costi gli agonisti del glp-1 come ozempic può essere segnalato ad ordine dei medici e denunciato per omesso soccorso malgrado glicata molto elevata?
Salve a tutti,
come si evince dalla domanda del post sono diabetico di tipo 2 ed ho valori glicemici molto elevati, anche in presenza di una dieta chetogenica la glicemia non scende sotto i 200. Sono stato visitato da un medico diabetologo della ASL mi sono presentato con analisi che hanno rilevato un valore di emoglobina glicata pari a 9,9 , piuttosto elevato. Pertanto sono stato diagnosticato con diabete di tipo 2, purtroppo data la mia attività professionale non posso permettermi gli effetti collaterali degli agonosti del glp-1, che possono essere pesanti ed anche invalidanti. Ho chiesto pertanto alla dottoressa di valutare la prescrizione di una terapia insulinica, vale la pena ricordarlo la piu' efficace di tutte le terapie disponibili, in quanto il principale effetto collaterale della terapia insulinica è l'ipoglicemia, un effetto collaterale a natura sporadica, che si può risolvere rapidamente, e che deve ,senza alcuna eccezione, saper essere gestito da un diabetologo realmente competente . La dottoressa non ci ha voluto sentire e mi ha obbligato ad accettare l'ozempic dicendo che dovevo riportare l'emoglobina glicata alla normalità, cosa che può fare benissimo anche l'insulina. Non ho naturalmente preso l'ozempic , ed ho provato a gestire la situazione come meglio potevo. Pertanto a mesi di distanza mi ritrovo con glicemia costantemente sopra 200, un senso di stanchezza cronica e perenne, e possibili complicazioni diabetiche per i costantemente elevati livelli di zucchero. La terapia insulinica, gestita da professionisti competenti, non mi avrebbe fatto perdere peso, ma avrebbe portato verso la normalizzazione della glicemia evitando un rischio così marcato di complicazioni diabetiche. La mia domanda è: la condotta della dottoressa è legalmente giustificata, ci sono gli estremi per l'omesso soccorso, è fondata una segnalazione all'ordine dei medici? Ringrazio già da ora chiunque volesse rispondermi, grazie.
submitted by Longjumping_Fly_2978 to Avvocati [link] [comments]
come si evince dalla domanda del post sono diabetico di tipo 2 ed ho valori glicemici molto elevati, anche in presenza di una dieta chetogenica la glicemia non scende sotto i 200. Sono stato visitato da un medico diabetologo della ASL mi sono presentato con analisi che hanno rilevato un valore di emoglobina glicata pari a 9,9 , piuttosto elevato. Pertanto sono stato diagnosticato con diabete di tipo 2, purtroppo data la mia attività professionale non posso permettermi gli effetti collaterali degli agonosti del glp-1, che possono essere pesanti ed anche invalidanti. Ho chiesto pertanto alla dottoressa di valutare la prescrizione di una terapia insulinica, vale la pena ricordarlo la piu' efficace di tutte le terapie disponibili, in quanto il principale effetto collaterale della terapia insulinica è l'ipoglicemia, un effetto collaterale a natura sporadica, che si può risolvere rapidamente, e che deve ,senza alcuna eccezione, saper essere gestito da un diabetologo realmente competente . La dottoressa non ci ha voluto sentire e mi ha obbligato ad accettare l'ozempic dicendo che dovevo riportare l'emoglobina glicata alla normalità, cosa che può fare benissimo anche l'insulina. Non ho naturalmente preso l'ozempic , ed ho provato a gestire la situazione come meglio potevo. Pertanto a mesi di distanza mi ritrovo con glicemia costantemente sopra 200, un senso di stanchezza cronica e perenne, e possibili complicazioni diabetiche per i costantemente elevati livelli di zucchero. La terapia insulinica, gestita da professionisti competenti, non mi avrebbe fatto perdere peso, ma avrebbe portato verso la normalizzazione della glicemia evitando un rischio così marcato di complicazioni diabetiche. La mia domanda è: la condotta della dottoressa è legalmente giustificata, ci sono gli estremi per l'omesso soccorso, è fondata una segnalazione all'ordine dei medici? Ringrazio già da ora chiunque volesse rispondermi, grazie.
2024.05.31 07:18 drchitra How is a high-risk pregnancy typically identified and diagnosed?
A high-risk pregnancy is identified and diagnosed through a combination of patient history, physical examinations, and diagnostic tests. Here’s a detailed overview of the process:
submitted by drchitra to u/drchitra [link] [comments]
1. Patient History and Risk Factors
- Medical History: Reviewing the patient’s medical history, including chronic conditions (e.g., diabetes, hypertension, autoimmune disorders).
- Obstetric History: Previous pregnancies and their outcomes (e.g., preterm birth, preeclampsia, miscarriages, or cesarean sections).
- Family History: Genetic or hereditary conditions that might affect the pregnancy.
- Lifestyle Factors: Smoking, alcohol consumption, drug use, and exposure to harmful substances.
- Age: Advanced maternal age (35 years and older) or very young age (teen pregnancies).
- Weight: Obesity or underweight conditions.
- Multiple Gestations: Carrying twins, triplets, or more.
2. Physical Examinations
- Baseline Vital Signs: Monitoring blood pressure, weight, and overall health.
- Gynecological Exam: Assessing the health of the reproductive organs.
3. Routine Prenatal Tests
- Blood Tests: Checking for anemia, blood type, Rh factor, infections (e.g., HIV, hepatitis, syphilis), and gestational diabetes.
- Urine Tests: Screening for protein, glucose, and infections.
- Ultrasound: Assessing fetal development, placental position, and amniotic fluid levels.
4. Specialized Tests and Monitoring
- Genetic Screening and Diagnostic Tests:
- First Trimester Screening: Blood tests and nuchal translucency ultrasound to assess risk for chromosomal abnormalities.
- Second Trimester Screening: Quad screen (AFP, hCG, Estriol, and Inhibin-A) for neural tube defects and chromosomal abnormalities.
- Amniocentesis or Chorionic Villus Sampling (CVS): For definitive genetic diagnosis.
- Fetal Echocardiography: Detailed ultrasound to assess fetal heart structure and function if congenital heart disease is suspected.
- Non-Stress Test (NST): Monitoring fetal heart rate in response to fetal movements.
- Biophysical Profile (BPP): Combines NST with ultrasound to check fetal well-being.
- Doppler Flow Studies: Assessing blood flow in the umbilical artery and other fetal vessels.
5. Maternal Health Monitoring
- Blood Pressure Monitoring: Frequent checks to detect preeclampsia or gestational hypertension.
- Blood Glucose Monitoring: For managing gestational diabetes.
- Weight and Nutritional Monitoring: Ensuring adequate weight gain and nutritional intake.
6. Hospital Visits and Specialist Referrals
- Frequent Prenatal Visits: More frequent visits to monitor the health of both mother and baby.
- Specialist Referrals: Consulting with maternal-fetal medicine specialists or other relevant specialists (e.g., endocrinologists, cardiologists) for specific conditions.
Identifying High-Risk Pregnancy Early
High-risk pregnancies are often identified early through routine prenatal care and the initial assessment of risk factors. Regular monitoring and specialized testing help in early detection and management, aiming to ensure the best possible outcomes for both mother and baby.2024.05.31 05:01 healthmedicinet Health Daily News May 28 2024
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5-28-2024
THE LIGHT OR THE CONTENT? WHAT WE KNOW ABOUT SCREENS AND SLEEP DISRUPTION
Too much screen time impairs sleep for children and adolescents, and it’s largely the content on those screens that keeps them awake. But it remains less clear whether the light from those screens also impairs sleep or whether and how screens directly disrupt adults’ sleep, too. That’s the consensus from 16 leading sleep experts, including two from CU Boulder, who published an exhaustive scientific review today on screen time and sleep in Sleep Health. “There’s a lot of research out there, but the messaging can5-28-2024
WHAT SHOULD WE FEAR WITH AI IN MEDICINE?
Will the threats associated with artificial intelligence be as bad as some fear? Or will AI be relatively benign? Could the answer be somewhere in between? Perspectives on AI abound. Whether it be in medicine, security or education, new applications in search of an AI advantage continue to grow. This has prompted calls for well-intentioned restraint and regulation or, at the very least, slower growth and proliferation. To alleviate some of that fear, we should consider one area in which5-28-2024
HOW TO KEEP FRUIT, VEGGIES AND HERBS FRESH FOR LONGER
We all know fresh produce is good for us, but fruit, vegetables and herbs have a tendency to perish quickly if left uneaten. This is because even after harvesting, produce from living plants tends to continue its biological processes. This includes respiration: producing energy from stored carbohydrates, proteins and fats while releasing carbon dioxide and water vapor. (Ever found a sprouting potato in your pantry?) On top of that, fresh produce also spoils easily thanks to various microbes—both harmless and ones that can cause disease, called pathogens. Simply chucking things5-28-2024
RESEARCHERS EXAMINE BLACK MEN’S PERCEPTIONS OF LABELING AFTER A VIOLENT FIREARM INJURY
The way Black men see themselves after a firearm injury—whether as a survivor or victim—could change over time and have implications on their mental health, according to a Rutgers Health study. The study, published in the Journal of Urban Health, examined the role of racially coded language, sociodemographic and environmental contexts that support labels among Black men who experienced a firearm injury. Rutgers researchers sought to understand how Black men in a hospital-based violence intervention program perceive “survivor” and “victim” labels after experiencing a firearm-related injury. “The self-identification as a5-28-2024
SCIENTISTS UNCOVER HOW OUR BRAINS TRY TO TELL THE DIFFERENCE BETWEEN MUSIC- AND SPEECH-LIKE NOISE
Music and speech are among the most frequent types of sounds we hear. But how do we identify what we think are differences between the two? An international team of researchers mapped out this process through a series of experiments—yielding insights that offer a potential means to optimize therapeutic programs that use music to regain the ability to speak in addressing aphasia. This language disorder afflicts more than one in 300 Americans each year, including Wendy Williams and Bruce Willis. “Although music and speech are different in many ways, ranging5-28-2024
MENTAL HEALTH BEGINS IN INFANCY, CHILD DEVELOPMENT EXPERTS TELL PARENTS
Did you know babies can get depressed? Andria Goss, associate vice president of clinical and community services at the Erikson Institute, a graduate school for social work, early childhood education and child development programs, said people are astonished when they learn and appreciate that fact. “Babies experience everything as a bodily feeling: If a parent is stressed, depressed and/or anxious, the baby is picking up on that,” she said. “Imagine a mom who has her own stresses and sometimes she’s able to focus on her baby and other times there’s5-28-2024
NEUROSCIENTISTS USE AI TO SIMULATE HOW THE BRAIN MAKES SENSE OF THE VISUAL WORLD
A research team at Stanford’s Wu Tsai Neurosciences Institute has made a major stride in using AI to replicate how the brain organizes sensory information to make sense of the world, opening up new frontiers for virtual neuroscience. Watch the seconds tick by on a clock and, in visual regions of your brain, neighboring groups of angle-selective neurons will fire in sequence as the second hand sweeps around the clock face. These cells form beautiful “pinwheel” maps, with each segment representing a visual perception of a different angle. Other visual5-28-2024
STUDY SHOWS ORANGE PEEL EXTRACT MAY IMPROVE HEART HEALTH
Orange peels may hold a key to better cardiovascular health, new University of Florida-led research shows. The findings are published in the Journal of Agricultural and Food Chemistry. Heart disease is the leading cause of death for men, women and people of most racial and ethnic groups, according to the Centers for Disease Control and Prevention. Recent research has shown that some gut bacteria help develop cardiovascular disease. When they feed on certain nutrients during digestion, gut bacteria produce trimethylamine N-oxide (TMAO). Levels of TMAO can help predict future cardiovascular5-28-2024
A NEW WAY TO CONTROL HIGH BLOOD SUGAR
Diabetes mellitus (DM) is a metabolic disease characterized by pancreatic malfunction and poor production of insulin. Imagine your pancreas is a factory for insulin, a key hormone that keeps your blood sugar level. Inside this factory are tiny assembly lines called pancreatic islets. When these islets get damaged, it’s like a mini-disaster in the factory. The assembly lines malfunction, and they can’t produce enough insulin. This can lead to5-28-2024
CDC WARNS AGAIN OF SALMONELLA TIED TO BACKYARD POULTRY
Backyard chickens are causing outbreaks of salmonella across the United States, the U.S. Centers for Disease Control and Prevention warns. About 109 people in 29 states have gotten sick from salmonella after touching or caring for backyard poultry, the CDC said in a health advisory. Of those, 33 people have been hospitalized, the CDC said. No deaths have been reported. More than 2 in 5 people affected by the outbreak are children younger than 5, the agency added. Backyard poultry can carry salmonella bacteria even if they look healthy and5-28-2024
CIRCUMCISION MAY REDUCE THE RISK OF HIV INFECTION
A randomized controlled trial comprised of 247 men who have sex with men (MSM) found that voluntary medical male circumcision (VMMC) can prevent incident HIV infection. These findings suggest that MSM should be included in VMMC guidelines. The study is published in Annals of Internal Medicine. Researchers from China enrolled uncircumcised, HIV-seronegative men aged 18 to 49 years who self-reported predominantly practicing insertive anal intercourse5-28-2024
SUGAR DOESN’T MAKE KIDS HYPERACTIVE, SUGGESTS NEUROSCIENTIST
It’s a Saturday afternoon at a kids’ birthday party. Hordes of children are swarming between the spread of birthday treats and party games. Half-eaten cupcakes, biscuits and lollies litter the floor, and the kids seem to have gained superhuman speed and bounce-off-the-wall energy. But is sugar to blame? The belief that eating sugary foods and drinks leads to hyperactivity has steadfastly persisted for decades. And parents have curtailed their children’s intake accordingly. Balanced nutrition is critical during childhood. As a neuroscientist who has studied the negative effects of high sugar5-28-2024
IF YOU CAN’T AFFORD AS MUCH FRESH PRODUCE, ARE CANNED VEGGIES OR FROZEN FRUIT JUST AS GOOD?
The cost of living crisis is affecting how we spend our money. For many people, this means tightening the budget on the weekly supermarket shop. One victim may be fresh fruit and vegetables. Data from the Australian Bureau of Statistics (ABS) suggests Australians were consuming fewer fruit and vegetables in 2022–23 than the year before. The cost of living is likely compounding a problem that exists already—on the whole, Australians don’t eat enough fruit and vegetables. Australian dietary guidelines recommend people aged nine and older should consume two serves of5-28-2024
PROMISING RESULTS FOR HYPERLIPIDEMIA TREATMENT REDUCE RISK OF CARDIOVASCULAR EVENTS
Research led by Baylor College of Medicine has shown that a new therapy significantly reduces triglyceride levels in individuals with mixed hyperlipidemia—elevations of triglycerides and cholesterol. The results, published in the latest edition of the New England Journal of Medicine, demonstrate how the drug plozasiran works by targeting ApoC3, which is a key regulator of the lipoprotein particles that carry triglyceride and cholesterol remnants versus overall LDL cholesterol levels. “This is a story about elevated triglycerides, which remain a problem in many individuals that I see in my practice,” said5-28-2024
STATINS ASSOCIATED WITH DECREASED RISK FOR CARDIOVASCULAR DISEASE AND DEATH, EVEN IN VERY OLD ADULTS
A study of adults aged 60 years and older found that the use of statin therapy as primary cardiovascular disease (CVD) prevention was effective for preventing CVD and all-cause mortality, even in adults aged 85 years and older. The study is published in Annals of Internal Medicine. Researchers from the University of Hong Kong used a target trial emulation design to investigate the relationship between statin therapy and CVD risk using electronic health records (EHRs) from the Hong Kong Hospital Authority. The study included adult patients over 60 without preexisting5-28-2024
SLEEP STUDY FINDS POST-KARAOKE STRESS IS STRENGTHENED BY REM SLEEP
We’re all familiar with the fact that the quality of our sleep has a strong impact on our waking lives. But what you may not know is that sleep stages contribute to how we process life experiences and memories in different ways. Deep sleep, or slow wave sleep (SWS), is associated with memory consolidation, which makes memories longer lasting. Our understanding of rapid eye movement (REM) sleep is less clear: although it is associated with the way we process emotions and how well we remember more emotionally charged experiences, there5-28-2024
FOR SOME ENDOMETRIOSIS-RELATED OVARIAN CANCERS, TIMING IS EVERYTHING
Two types of endometriosis-related ovarian cancer arise from the same cells but likely at different stages of the menstrual cycle—a nuance that significantly influences treatment response, reports a recent study led by Van Andel Institute and University of British Columbia scientists. The findings, published in the journal Cancer Research, have implications for better understanding and treating a pair of cancer subtypes that together account for up to nearly a5-28-2024
PRENATAL EXPOSURE TO AIR POLLUTION ASSOCIATED WITH INCREASED MENTAL HEALTH RISKS
A baby’s exposure to air pollution while in the womb is associated with the development of certain mental health problems once the infant reaches adolescence, new research has found. The University of Bristol-led study, published in JAMA Network Open on May 28, examined the long-term mental health impact of early-life exposure to air and noise pollution. Growing evidence suggests5-28-2024
FOUR WAYS VACCINE SKEPTICS MISLEAD ON MEASLES AND MORE
Measles is on the rise in the United States. In the first quarter of this year, the number of cases was about 17 times what it was, on average, during the same period in each of the four years before, according to the Centers for Disease Control and Prevention. Half of the people infected— mainly children—have been hospitalized. It’s going to get worse, largely because a growing number of parents are deciding not to get their children vaccinated against measles as well as diseases like polio and pertussis. Unvaccinated people,5-28-2024
CANCER RESEARCHERS DISCOVER OPTIMAL CANCER-KILLING T CELLS
A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies. T cell-based immunotherapy has tremendous value to fight, and often eliminate, cancer. The strategy activates a patient’s immune system and engineers a patient’s own T cells to recognize, attack and kill cancer cells. In this way, the body’s own T cells become living drugs. While5-28-2024
AIR POLLUTION DURING PREGNANCY LINKED TO LOW BIRTH WEIGHT, STUDY FINDS
A recent study has uncovered a troubling link between exposure to PM2.5 air pollution during pregnancy and the risk of low birth weight in newborns. This study highlights the significant impact of air quality on prenatal development and emphasizes the urgent need for stricter air pollution controls.5-28-2024
DEEP LEANING TECHNOLOGY SHOWS POTENTIAL IN PHOTODYNAMIC THERAPY
In contrast to traditional cancer treatments such as surgery, chemotherapy, and radiotherapy, photodynamic therapy (PDT) is emerging as a novel5-28-2024
3 CHILDREN HOSPITALIZED IN PUERTO RICO AFTER LIGHTNING STRIKES BEACH
Did you know: lightning can strike the same place multiple times? For example, the Empire State Building is reportedly struck by lightning roughly 23 times per year. Lightning struck a beach in the northern coastal town of Isabela during inclement weather Monday, injuring three children, one seriously, Puerto Rican police said. The children, whose ages ranged from 7 to 12, were taken to a hospital in the nearby town of Aguadilla, a police statement said. The oldest youngster was listed in serious condition, it said. No further details were released.5-28-2024
CAFFEINE SHOWN TO AFFECT BRAIN DOPAMINE FUNCTION IN PATIENTS WITH PARKINSON’S DISEASE
The effects of high and low consumption of caffeine on the brain’s dopamine transporter binding in patients diagnosed with Parkinson’s disease. Regular high caffeine consumption affects dopamine function in patients with Parkinson’s disease, shows a new international study led by the University of Turku and Turku University Hospital in Finland. Caffeine consumption before undergoing diagnostic brain dopamine imaging may also affect the imaging results. The research results were published in the Annals of Neurology on 20 May 2024. Previous research has shown that5-28-2024
STUDY REVEALS CIRCADIAN CLOCK CAN BE LEVERAGED TO ENHANCE CANCER IMMUNOTHERAPY
STUDY FINDS BLOOD CLOT RISK IS INFLUENCED BY ANGLE AT WHICH PULMONARY VEINS REACH THE HEART
5-28-2024LIGHT THERAPY INCREASES BRAIN CONNECTIVITY FOLLOWING INJURY, STUDY FINDS
5-28-2024STUDY SHOWS OVERLOOKED LIPID IS CONNECTED TO ANCIENT CELLULAR PATHWAY WITH LINKS TO CANCER
5-28-2024RESEARCH IDENTIFIES MECHANISMS FOR SELECTIVE MULTIPLE SCLEROSIS TREATMENT STRATEGY
5-28-2024CHATBOTS ARE POOR MULTILINGUAL HEALTH CARE CONSULTANTS, STUDY FINDS
5-28-2024COUNTRIES AT ODDS OVER HOW TO REIGNITE PANDEMIC AGREEMENT
5-28-2024SILIBININ, AN OLD AND NEW MOLECULE
5-28-2024NEW REPORT REVEALS FATHERHOOD’S HIDDEN HEART HEALTH TOLL
5-28-2024WHAT HAPPENS WHEN AUDITORY CUES AFFECT BODY REPRESENTATION AND VICE-VERSA?
5-28-2024TARGETING ‘MONSTER CANCER CELLS’ COULD REDUCE RECURRENCE RATES AFTER CANCER THERAPY
5-28-2024RESEARCHERS PROPOSE SURGICAL ALGORITHM FOR NASAL ALAR DEFECTS IN ASIAN PATIENTS
5-28-2024EFFECTIVE LYMPH NODE TRANSFER EASES ARM SWELLING IN BREAST CANCER PATIENTS
5-28-2024INVESTIGATING HYPERACTIVATION OF MEMORY CIRCUITS AND ALZHEIMER’S DISEASE RISK
5-28-2024RESEARCHERS DEVELOP 3D MODEL TO BETTER TREAT NEUROLOGICAL DISORDERS
5-28-2024EXTERNAL VENTRICULAR DRAINAGE TIMING IN TRAUMATIC BRAIN INJURY MAY RESULT IN BETTER LONG-TERM FUNCTIONAL OUTCOMES
5-28-2024RESEARCHERS GENETICALLY MODIFY E. COLI BACTERIA WITH PART OF HIV VIRUS IN BID FOR SUCCESSFUL VACCINE
5-28-2024NEW STUDY SHOWS ABDOMINAL OBESITY AND MUSCLE WEAKNESS IN 8-YEAR-OLDS
5-28-2024EXTRACORPOREAL SHOCK-WAVE LITHOTRIPSY, ENDOSCOPY BENEFICIAL FOR PANCREATITIS
5-28-2024CONSIDERABLE VARIATION SEEN IN MORTALITY RATES FOR SUSPECTED SEPSIS
5-28-2024CONJUGATED EQUINE ESTROGEN MAY INCREASE RISK FOR OVARIAN CANCER
5-28-2024RISING COSTS OF HEALTH CARE COVERAGE CONTINUE TO PUT FINANCIAL STRAIN ON EVEN THE PRIVATELY INSURED
5-28-2024RESEARCHERS URGE IMMEDIATE ALCOHOL REGULATION TO CURB VIOLENCE AGAINST WOMEN, KIDS
5-28-2024STUDY OF DEADLY AUSTRALIAN JAPANESE ENCEPHALITIS VIRUS STRAIN PROMPTS PUSH FOR NEW VACCINE
5-28-2024STUDY FINDS TEXT REMINDERS HELP IMPROVE HEALTH CARE WORKERS’ MENTAL HEALTH
5-28-2024RESEARCHERS DEVELOP MINIMALLY INVASIVE SCAFFOLD DELIVERY SYSTEM USING DYNAMIC THERMOSET POLYURETHANE
5-28-2024MIGRANTS MUST BE A FOCUS OF CATCH-UP VACCINATION CAMPAIGNS, WARN GLOBAL HEALTH EXPERTS
5-28-2024SPECIFIC MICROBIAL HALLMARKS IN VAGINA COULD INDICATE GYNECOLOGICAL CANCERS
5-28-2024PEOPLE COMING OFF ANTIDEPRESSANTS ARE LOOKING FOR HELP ONLINE, UNDERSCORING A GAP IN TRADITIONAL CLINICAL PRACTICES
5-28-2024CASES OF BACTERIAL DISEASE RISE IN BRAZIL’S FLOODED SOUTH
5-28-2024MEASLES CASES SURGING AGAIN IN EUROPE: WHO
5-28-2024ETHICAL APPROACHES TO MITIGATE H5N1 BIRD FLU
5-28-2024PHARMACISTS PROVE EFFECTIVE, LESS COSTLY CARE OPTION FOR MINOR ILLNESSES
5-28-2024RESEARCHERS IDENTIFY PROMISING PROTEIN CANDIDATE FOR METABOLIC DISEASE TREATMENT
5-28-2024NEXT-GEN KNEE TRAINING MODEL HEADS FOR GLOBAL MARKETS
5-28-2024POTENTIAL FUTURE TARGET FOR TREATING PRIMARY HEADACHE DISORDERS IDENTIFIED
5-28-2024
GENETIC MOSAICISM MORE COMMON THAN THOUGHT, STUDY SHOWS
5-28-2024
NEW SEQUENCING METHOD ANALYZES LUNG MICROBIOMES TO PREDICT MORTALITY IN CHILDREN FOLLOWING BONE MARROW TRANSPLANT
5-28-2024
RESEARCH HIGHLIGHTS URGENT NEED TO TACKLE HEALTH CHALLENGES FOR MIGRANTS IN EUROPE
5-28-2024
ONE IN EIGHT PREGNANT PEOPLE HAVE A DISABILITY, BUT REPORT SHOWS GAPS EXIST IN THE PROVISION OF ACCESSIBLE CARE
5-28-2024
BINGE-EATING DISORDER NOT AS TRANSIENT AS PREVIOUSLY THOUGHT
5-28-2024SAN DIEGO’S BIGGEST MEDICAL PROVIDER IS ALL IN ON ROBOT-ASSISTED SURGERY
5-28-2024
RESEARCHERS REFORMULATE ANTIPSYCHOTIC DRUGS WITH COATING THAT MITIGATES WEIGHT GAIN, BOOSTS SEROTONIN
5-28-2024
STUDY DEMONSTRATES HOW CYTOKINES PRODUCE LONG LASTING HUMORAL IMMUNITY FOLLOWING VACCINATION
5-28-2024
ENGINEERED CAR T CELLS REPRESS SIGNS AND SYMPTOMS OF ALLERGIC ASTHMA IN MICE FOR A YEAR
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NEW SWEAT MONITORING DEVICE DOESN’T REQUIRE PHYSICAL ACTIVITY
5-28-2024MATHEMATICAL MODEL EXPLOITS CANCER CELL PLASTICITY TO GUIDE ADAPTIVE THERAPY
5-28-2024RESEARCHERS DISCOVER NOVEL METHOD TO PREDICT EFFECTIVENESS OF MESENCHYMAL STROMAL CELLS FOR CARTILAGE REPAIR
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RESEARCHERS IDENTIFY ‘DEGREES OF KEVIN BACON’ GENE IN WELL-CONNECTED FRUIT FLIES
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STUDY POINTS TO NEW COMBINATION STRATEGY FOR PANCREATIC CANCER
5-28-2024RESEARCHERS ESTABLISH MICROFLUIDIC CONTROL TECHNOLOGY FOR BLOOD TESTING DEVICES
5-28-2024PROTEOMIC SIGNATURES MAY INDICATE MRI-ASSESSED LIVER FAT
5-28-2024RESEARCHERS ESTABLISH MICROFLUIDIC CONTROL TECHNOLOGY FOR BLOOD TESTING DEVICES
5-28-2024PROTEOMIC SIGNATURES MAY INDICATE MRI-ASSESSED LIVER FAT
2024.05.31 04:32 farcry5pro Is this rare to see in era 7?
 | https://preview.redd.it/n9cyc07ebo3d1.png?width=1366&format=png&auto=webp&s=d45fb5cf28930848c763a1cc28cc6e915eaf44b7 submitted by farcry5pro to SolsRNG [link] [comments] (I'm the virtual) |
2024.05.31 04:30 farcry5pro Is this rare to see in era 7?
 | https://preview.redd.it/1qv4wh90bo3d1.png?width=1366&format=png&auto=webp&s=12357563501ebcbd1a3b5ca1dc38157faf485a2d submitted by farcry5pro to SolsRNG [link] [comments] (I'm the virtual) |
2024.05.31 01:53 nkbl_dog Toddler wants to eat all the time, even after full meals
Hi everyone,
I would love advice about my 21 month old. She has always been a great eater, she is not picky at all, and eats what we eat. The problem is that she wants to eat ALL the time. She eats full meals 3 times a day and I think her portions are quite big (i.e. 2 sausages, toast, cucumber, 3 lamb chops, broccoli, sweet potatoes/ 2 chicken drumsticks, cabbage, blueberries, etc.) She will not stop eating, I always have to cut her off or she will keep eating. Her tummy gets so full and hard after meals.
In between meals, she is always saying "more eat." I try to stick with one snack between breakfast and lunch and then one after her snack. We just went on a trip away and she was literally begging for food the whole time, even in new, exciting environments. I feel like it impacts her day to day life because she is always just thinking of food and nothing else. If she sees food or we say a word that is food related, she will just beg for it.
Many people told me it is a growth spurt, but she is always like this. I know she is growing in general, but I worry health wise if this is some issue with malabsorption, blood sugar issues, type 1 diabetes (doesn't match any other symptoms and no fam history). I will be bringing this up with her doctor next month at our appointment.
Anyway, I am looking for parents of toddlers who are non-stop eaters. Not snackers, which I know is typical, but literally 3 full adult meals plus she as many snacks as I will give her. I would also love to hear from parents whose kids were like this as toddlers and how they are doing now being older.
Thank you so much!
submitted by nkbl_dog to toddlers [link] [comments]
I would love advice about my 21 month old. She has always been a great eater, she is not picky at all, and eats what we eat. The problem is that she wants to eat ALL the time. She eats full meals 3 times a day and I think her portions are quite big (i.e. 2 sausages, toast, cucumber, 3 lamb chops, broccoli, sweet potatoes/ 2 chicken drumsticks, cabbage, blueberries, etc.) She will not stop eating, I always have to cut her off or she will keep eating. Her tummy gets so full and hard after meals.
In between meals, she is always saying "more eat." I try to stick with one snack between breakfast and lunch and then one after her snack. We just went on a trip away and she was literally begging for food the whole time, even in new, exciting environments. I feel like it impacts her day to day life because she is always just thinking of food and nothing else. If she sees food or we say a word that is food related, she will just beg for it.
Many people told me it is a growth spurt, but she is always like this. I know she is growing in general, but I worry health wise if this is some issue with malabsorption, blood sugar issues, type 1 diabetes (doesn't match any other symptoms and no fam history). I will be bringing this up with her doctor next month at our appointment.
Anyway, I am looking for parents of toddlers who are non-stop eaters. Not snackers, which I know is typical, but literally 3 full adult meals plus she as many snacks as I will give her. I would also love to hear from parents whose kids were like this as toddlers and how they are doing now being older.
Thank you so much!
2024.05.31 00:04 AEGISAlliance CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Referral Code: ZULMHXXVCB Solid advice for new plasma donors included! Thank you!
Link to download app:
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
submitted by AEGISAlliance to PlasmaReferrals [link] [comments]
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
- Plasma is 92% water and the rest is mostly protein elements.
- The plasma is separated from your blood and your red blood cells are returned to you in cycles.
- Per FDA regulations, you're only allowed to donate plasma twice in a 7 day period, with a 48 hour wait inbetween those two times. Don't risk your health by hopping around to different plasma donation centers to circumvent these regulations, and you may get caught if you do.
- Eat a meal high in protein 2-3 hours before donating, but your plasma protein levels depend on what you ate the day before.
- Drink plenty of water and/or non-caffeinated juice before donating to stay hydrated.
- Avoid caffeine such as in coffee or soda before donating or you may get nauseous and vomit or faint during your donation.
- No alcohol 24 hours before, and for a little while after donating.
- No exercising for at least 6 hours after donating as it can put too much stress on the vein.
- Some people get away with smoking or vaping nicotine before and after donating, but it's recommended not to for 2 hours before and after. The nicotine can raise your heart's pulse rate.
- If your pulse rate is 100 or above, you'll be able to do a vitals retake after a 15 minute wait. But if it's 100 or higher again you'll be deferred for the day. If your pulse rate is an issue, listen to "Pink Noise" or "Green Noise" at a low volume before donating which may help reduce your pulse rate, along with its effect on lowering your blood pressure.
- There is a risk of getting a blown vein if the worker is having a hard time finding your vein when they're sticking you with the needle or if you have small veins. You may get deferred until your vein heals if that happens. But it's ok, your body is able to regenerate your veins with a process called Angiogenesis.
- There is a risk of blood clots, but when your blood is constantly moving through the machine it prevents that from happening.
- You may be subject to drug screening. The drug screening tests for methamphetamines, cocaine, and heroin. Certain pharma prescription meds may show up as a false positive so you'll want to let the plasma center know what meds you're taking. Testing positive for these drugs can result in a permanent deferral from donating plasma.
- A sample of your blood will be drawn periodically to test for certain sexually transmitted infections (STIs). A positive test will result in either a temporary or permanent deferral from donating plasma. If you've ever been diagnosed or received treatment for HIV/AIDS, Hepatitis B (HBV) or Hepatitis C (HCV) you will be permanently deferred from donating plasma.
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
- Healthy Feet: Active foot ulcers requiring medical attention will disqualify you from donation.
- Steady Balance: You shouldn't experience dizziness or lightheadedness upon standing.
- Type 1 Consideration: For Type 1 diabetics, eating within two hours of donation is mandatory.
- Wait a few hours before taking the bandage wrap off of your arm after donating.
- It's recommended to use Vitamin E oil/Mineral oil on the needle site for the puncture area to heal better. A Q-tip can be used to apply it easier. I simply dip the Q-Tip in the bottle, but never dip the used cotton back into the bottle.
- Frequently donating over a prolonged period of time may lead to your body having decreased vitamin D levels.
- Red meats are particularly high in the protein vitamins and minerals found in plasma.
- Personally, I take a Now brand Vitamin D supplement that contains vitamin D3, Calcium, Magnesium, and Zinc. But I only take a half a dose, 1 gel capsule instead of 2, since I get these from eating meats and other foods as well. It's bad for your health if you take too much of these vitamins and minerals over time. I also take an Iron supplement. I also drink a protein shake before donating. Just to be safe.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
2024.05.30 21:29 AEGISAlliance CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Referral Code: ZULMHXXVCB Solid advice for new plasma donors included! Thank you!
Link to download app:
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
submitted by AEGISAlliance to CSLPlasmaReferrals [link] [comments]
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
I have advice for new plasma donors who may be considering to try it out and earn extra money:
- Plasma is 92% water and the rest is mostly protein elements.
- The plasma is separated from your blood and your red blood cells are returned to you in cycles.
- Per FDA regulations, you're only allowed to donate plasma twice in a 7 day period, with a 48 hour wait inbetween those two times. Don't risk your health by hopping around to different plasma donation centers to circumvent these regulations, and you may get caught if you do.
- Eat a meal high in protein 2-3 hours before donating, but your plasma protein levels depend on what you ate the day before.
- Drink plenty of water and/or non-caffeinated juice before donating to stay hydrated.
- Avoid caffeine such as in coffee or soda before donating or you may get nauseous and vomit or faint during your donation.
- No alcohol 24 hours before, and for a little while after donating.
- No exercising for at least 6 hours after donating as it can put too much stress on the vein.
- Some people get away with smoking or vaping nicotine before and after donating, but it's recommended not to for 2 hours before and after. The nicotine can raise your heart's pulse rate.
- If your pulse rate is 100 or above, you'll be able to do a vitals retake after a 15 minute wait. But if it's 100 or higher again you'll be deferred for the day. If your pulse rate is an issue, listen to "Pink Noise" or "Green Noise" at a low volume before donating which may help reduce your pulse rate, along with its effect on lowering your blood pressure.
- There is a risk of getting a blown vein if the worker is having a hard time finding your vein when they're sticking you with the needle or if you have small veins. You may get deferred until your vein heals if that happens. But it's ok, your body is able to regenerate your veins with a process called Angiogenesis.
- There is a risk of blood clots, but when your blood is constantly moving through the machine it prevents that from happening.
- You may be subject to drug screening. The drug screening tests for methamphetamines, cocaine, and heroin. Certain pharma prescription meds may show up as a false positive so you'll want to let the plasma center know what meds you're taking. Testing positive for these drugs can result in a permanent deferral from donating plasma.
- A sample of your blood will be drawn periodically to test for certain sexually transmitted infections (STIs). A positive test will result in either a temporary or permanent deferral from donating plasma. If you've ever been diagnosed or received treatment for HIV/AIDS, Hepatitis B (HBV) or Hepatitis C (HCV) you will be permanently deferred from donating plasma.
Individuals with well-controlled diabetes can contribute to plasma donation, but certain criteria need to be met:
Absence of Complications: This means no existing diabetic complications affecting your kidneys, heart, blood vessels, or eyes.
Insulin Independence: If you rely on insulin for diabetes management, a three-month waiting period is required after using needles for non-prescribed medications. Additionally, you must be free of symptoms or treatment needs related to blood sugar fluctuations (high or low) for the past three months.
- Healthy Feet: Active foot ulcers requiring medical attention will disqualify you from donation.
- Steady Balance: You shouldn't experience dizziness or lightheadedness upon standing.
- Type 1 Consideration: For Type 1 diabetics, eating within two hours of donation is mandatory.
- Wait a few hours before taking the bandage wrap off of your arm after donating.
- It's recommended to use Vitamin E oil/Mineral oil on the needle site for the puncture area to heal better. A Q-tip can be used to apply it easier. I simply dip the Q-Tip in the bottle, but never dip the used cotton back into the bottle.
- Frequently donating over a prolonged period of time may lead to your body having decreased vitamin D levels.
- Red meats are particularly high in the protein vitamins and minerals found in plasma.
- Personally, I take a Now brand Vitamin D supplement that contains vitamin D3, Calcium, Magnesium, and Zinc. But I only take a half a dose, 1 gel capsule instead of 2, since I get these from eating meats and other foods as well. It's bad for your health if you take too much of these vitamins and minerals over time. I also take an Iron supplement. I also drink a protein shake before donating. Just to be safe.
~https://rewards.cslplasma.com/referral/referral-unique-code/eyJkb25vcklEIjoiMDBEMjNEVSIsImNvZGUiOiJaVUxNSFhYVkNCIn0~
CSL Plasma: Get 5,000 iGive Rewards® points ($50) after five donations for new donors! (Plus new donor bonus money) Using the CSL Plasma app! Code: ZULMHXXVCB Thank you!
Code: ZULMHXXVCB
2024.05.30 20:40 CureEZ_Healthtech Diabetes Pain Relief: The Ultimate Guide to Effective Pain Management Strategies
Why is there a need for pain management?
Chronic pain is a common and debilitating issue for individuals living with diabetes, significantly impacting their quality of life. From neuropathic pain to musculoskeletal discomfort, the challenges are numerous and often overwhelming. Effective pain management is crucial for optimal diabetes control and overall well-being, allowing individuals to lead more comfortable and fulfilling lives. In this guide, we will explore the various strategies available to manage diabetes-related pain, providing a comprehensive overview of pharmacological and non-pharmacological approaches.
Understanding Diabetes-Related Pain
Diabetes can lead to a variety of pain types, each with distinct characteristics and underlying causes. Understanding these can help in formulating an effective pain management plan.
Neuropathic Pain
Neuropathic pain is caused by nerve damage, a common complication of diabetes, particularly in individuals with poorly controlled blood sugar levels. This type of pain often manifests as burning, tingling, or shooting sensations, typically in the hands and feet. The condition, known as diabetic peripheral neuropathy, can be severe and persistent, significantly affecting mobility and daily activities.
Musculoskeletal Pain
Musculoskeletal pain in diabetes can arise from various sources, including joint problems, muscle aches, and connective tissue disorders. Conditions such as diabetic cheiroarthropathy (limited joint mobility), frozen shoulder, and carpal tunnel syndrome are more prevalent in individuals with diabetes. This pain can limit movement and functionality, further complicating diabetes management.
Pain from Complications
Diabetes can lead to serious complications such as ulcers and amputations, which are often accompanied by intense pain. Poor circulation and neuropathy contribute to the development of these complications, making prevention and proper treatment essential. The pain from these complications can be both physically and emotionally draining, underscoring the need for comprehensive pain management strategies.
Underlying Mechanisms
The pain associated with diabetes arises from various mechanisms:
Alternative approaches to diabetes related pain management
Pharmacological Approaches Pain Management Strategies
Pharmacological treatments play a vital role in managing diabetes-related pain. These include a range of prescription medications designed to alleviate different types of pain.
Analgesics
Common pain relievers such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) can help manage mild to moderate pain. However, their use should be monitored due to potential side effects, including gastrointestinal issues and kidney damage, especially in long-term use.
Anti-Seizure Drugs
Medications like gabapentin and pregabalin are often prescribed for neuropathic pain. These drugs work by stabilizing nerve activity, reducing pain signals. While effective, they can cause side effects such as dizziness, fatigue, and weight gain.
Antidepressants
Certain antidepressants, particularly tricyclic antidepressants (e.g., amitriptyline) and serotonin-norepinephrine reuptake inhibitors (SNRIs, e.g., duloxetine), are also used to treat neuropathic pain. These medications can help by altering the way the brain processes pain. Side effects may include dry mouth, constipation, and drowsiness, necessitating careful management.
Working with Healthcare Providers
It is crucial to work closely with healthcare providers when using prescription medications for pain management. They can help tailor treatments to individual needs, monitor for side effects, and adjust dosages as necessary. Open communication with healthcare providers ensures a balanced approach to pain relief while minimizing risks.
Non-Pharmacological Pain Management Strategies
In addition to medications, several non-drug interventions can effectively manage diabetes-related pain. These strategies often complement pharmacological treatments, providing a holistic approach to pain management.
Physical Therapy and Exercise Programs
Physical therapy can help alleviate pain and improve mobility through targeted exercises and therapies. Regular physical activity, such as walking, swimming, or cycling, can enhance circulation, reduce inflammation, and strengthen muscles, contributing to overall pain relief. Physical therapists can design personalized exercise programs that cater to individual abilities and limitations.
Cognitive-Behavioral Therapy and Mindfulness Practices
Cognitive-behavioral therapy (CBT) and mindfulness practices can significantly impact pain perception and coping strategies. CBT helps individuals reframe negative thoughts about pain, reducing its psychological impact. Mindfulness practices, including meditation and deep-breathing exercises, promote relaxation and reduce stress, which can exacerbate pain.
Dietary Modifications and Nutritional Supplements
Diet plays a critical role in managing both diabetes and related pain. Anti-inflammatory diets rich in fruits, vegetables, whole grains, and lean proteins can help reduce pain and inflammation. Nutritional supplements such as omega-3 fatty acids, vitamin D, and magnesium may also provide pain relief. Consulting with a dietitian can ensure a balanced and effective dietary approach.
Complementary Therapies
Several complementary therapies have shown promise in managing diabetes-related pain:
Why Choose CureEZ?
CureEZ stands out as a leader in comprehensive pain management for individuals with diabetes. Our approach is rooted in a deep understanding of the complexities of diabetes-related pain and a commitment to providing personalized, effective solutions.
Expertise and Experience
Our team of healthcare professionals includes specialists in endocrinology, pain management, physical therapy, and nutrition, ensuring a multidisciplinary approach to pain relief. With years of experience and a dedication to staying at the forefront of medical advancements, CureEZ offers expert care tailored to each patient's needs.
Personalized Care Plans
At CureEZ, we recognize that every individual's pain experience is unique. We take the time to understand each patient's specific pain patterns, lifestyle, and medical history, creating personalized care plans that address their particular needs. Our holistic approach integrates pharmacological treatments, non-drug interventions, and lifestyle modifications for comprehensive pain relief.
Patient-Centered Approach
Our patient-centered philosophy means that we prioritize the comfort, preferences, and overall well-being of our patients. We believe in empowering individuals with the knowledge and tools they need to manage their pain effectively. Through education, support, and compassionate care, we help our patients take control of their pain and improve their quality of life.
Real-Life Examples of CureEZ patients.
Savitha's Journey to Pain Relief
Savitha, a 55-year-old woman with type 2 diabetes, had been struggling with severe neuropathic pain in her feet for years. Despite trying various medications, she found little relief and her quality of life was diminishing. After seeking help from CureEZ, Savitha underwent a comprehensive evaluation. Our team developed a personalized care plan that included a combination of gabapentin, physical therapy, and dietary modifications. Additionally, Savitha started regular acupuncture sessions and mindfulness practices. Within months, her pain levels decreased significantly, and she regained her mobility and zest for life.
Gangadhar's Success Story
Gangadhar, a 60-year-old man with a long history of diabetes, suffered from chronic musculoskeletal pain and complications from a foot ulcer. Traditional pain medications provided limited relief, and he faced the prospect of amputation. At CureEZ, we implemented a multifaceted approach to his pain management. Gangadhar's treatment included antidepressants for pain relief, a tailored exercise program, and nutritional supplements to support healing. Complementary therapies like massage and TENS were also introduced. With this comprehensive plan, Gangadhar's pain improved, his ulcer healed, and he avoided amputation, allowing him to continue his daily activities with much less discomfort.
Conclusion
Effective pain management is essential for individuals with diabetes to maintain their quality of life and overall well-being. By understanding the different types of pain associated with diabetes and exploring both pharmacological and non-pharmacological strategies, individuals can find relief and improve their daily functioning. CureEZ is committed to providing comprehensive, personalized pain management solutions, helping patients like Savitha and Gangadhar lead healthier, more comfortable lives. If you are struggling with diabetes-related pain, reach out to CureEZ for a tailored approach to pain relief and experience the difference in quality care.
References
https://diabetes.org/about-diabetes/complications
https://www.mayoclinic.org/diseases-conditions/diabetic-neuropathy/symptoms-causes/syc-20371580
https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies
https://www.health.harvard.edu/topics/diabetes
https://www.hopkinsmedicine.org/health/conditions-and-diseases/peripheral-neuropathy
submitted by CureEZ_Healthtech to u/CureEZ_Healthtech [link] [comments]
Chronic pain is a common and debilitating issue for individuals living with diabetes, significantly impacting their quality of life. From neuropathic pain to musculoskeletal discomfort, the challenges are numerous and often overwhelming. Effective pain management is crucial for optimal diabetes control and overall well-being, allowing individuals to lead more comfortable and fulfilling lives. In this guide, we will explore the various strategies available to manage diabetes-related pain, providing a comprehensive overview of pharmacological and non-pharmacological approaches.
Understanding Diabetes-Related Pain
Diabetes can lead to a variety of pain types, each with distinct characteristics and underlying causes. Understanding these can help in formulating an effective pain management plan.
Neuropathic Pain
Neuropathic pain is caused by nerve damage, a common complication of diabetes, particularly in individuals with poorly controlled blood sugar levels. This type of pain often manifests as burning, tingling, or shooting sensations, typically in the hands and feet. The condition, known as diabetic peripheral neuropathy, can be severe and persistent, significantly affecting mobility and daily activities.
Musculoskeletal Pain
Musculoskeletal pain in diabetes can arise from various sources, including joint problems, muscle aches, and connective tissue disorders. Conditions such as diabetic cheiroarthropathy (limited joint mobility), frozen shoulder, and carpal tunnel syndrome are more prevalent in individuals with diabetes. This pain can limit movement and functionality, further complicating diabetes management.
Pain from Complications
Diabetes can lead to serious complications such as ulcers and amputations, which are often accompanied by intense pain. Poor circulation and neuropathy contribute to the development of these complications, making prevention and proper treatment essential. The pain from these complications can be both physically and emotionally draining, underscoring the need for comprehensive pain management strategies.
Underlying Mechanisms
The pain associated with diabetes arises from various mechanisms:
- Nerve Damage: High blood sugar levels can damage nerves, leading to neuropathic pain.
- Inflammation: Chronic inflammation, a common issue in diabetes, can cause and exacerbate pain.
- Poor Circulation: Vascular issues resulting from diabetes can lead to pain, particularly in the lower extremities, where blood flow is often compromised.
Alternative approaches to diabetes related pain management
Pharmacological Approaches Pain Management Strategies
Pharmacological treatments play a vital role in managing diabetes-related pain. These include a range of prescription medications designed to alleviate different types of pain.
Analgesics
Common pain relievers such as acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) can help manage mild to moderate pain. However, their use should be monitored due to potential side effects, including gastrointestinal issues and kidney damage, especially in long-term use.
Anti-Seizure Drugs
Medications like gabapentin and pregabalin are often prescribed for neuropathic pain. These drugs work by stabilizing nerve activity, reducing pain signals. While effective, they can cause side effects such as dizziness, fatigue, and weight gain.
Antidepressants
Certain antidepressants, particularly tricyclic antidepressants (e.g., amitriptyline) and serotonin-norepinephrine reuptake inhibitors (SNRIs, e.g., duloxetine), are also used to treat neuropathic pain. These medications can help by altering the way the brain processes pain. Side effects may include dry mouth, constipation, and drowsiness, necessitating careful management.
Working with Healthcare Providers
It is crucial to work closely with healthcare providers when using prescription medications for pain management. They can help tailor treatments to individual needs, monitor for side effects, and adjust dosages as necessary. Open communication with healthcare providers ensures a balanced approach to pain relief while minimizing risks.
Non-Pharmacological Pain Management Strategies
In addition to medications, several non-drug interventions can effectively manage diabetes-related pain. These strategies often complement pharmacological treatments, providing a holistic approach to pain management.
Physical Therapy and Exercise Programs
Physical therapy can help alleviate pain and improve mobility through targeted exercises and therapies. Regular physical activity, such as walking, swimming, or cycling, can enhance circulation, reduce inflammation, and strengthen muscles, contributing to overall pain relief. Physical therapists can design personalized exercise programs that cater to individual abilities and limitations.
Cognitive-Behavioral Therapy and Mindfulness Practices
Cognitive-behavioral therapy (CBT) and mindfulness practices can significantly impact pain perception and coping strategies. CBT helps individuals reframe negative thoughts about pain, reducing its psychological impact. Mindfulness practices, including meditation and deep-breathing exercises, promote relaxation and reduce stress, which can exacerbate pain.
Dietary Modifications and Nutritional Supplements
Diet plays a critical role in managing both diabetes and related pain. Anti-inflammatory diets rich in fruits, vegetables, whole grains, and lean proteins can help reduce pain and inflammation. Nutritional supplements such as omega-3 fatty acids, vitamin D, and magnesium may also provide pain relief. Consulting with a dietitian can ensure a balanced and effective dietary approach.
Complementary Therapies
Several complementary therapies have shown promise in managing diabetes-related pain:
- Acupuncture: This traditional Chinese medicine technique involves inserting thin needles into specific points on the body to relieve pain and improve energy flow.
- Massage Therapy: Regular massage can reduce muscle tension, improve circulation, and promote relaxation, helping to alleviate pain.
- Transcutaneous Electrical Nerve Stimulation (TENS): TENS involves using a device to send electrical impulses through the skin, which can help reduce pain by interfering with pain signals.
Why Choose CureEZ?
CureEZ stands out as a leader in comprehensive pain management for individuals with diabetes. Our approach is rooted in a deep understanding of the complexities of diabetes-related pain and a commitment to providing personalized, effective solutions.
Expertise and Experience
Our team of healthcare professionals includes specialists in endocrinology, pain management, physical therapy, and nutrition, ensuring a multidisciplinary approach to pain relief. With years of experience and a dedication to staying at the forefront of medical advancements, CureEZ offers expert care tailored to each patient's needs.
Personalized Care Plans
At CureEZ, we recognize that every individual's pain experience is unique. We take the time to understand each patient's specific pain patterns, lifestyle, and medical history, creating personalized care plans that address their particular needs. Our holistic approach integrates pharmacological treatments, non-drug interventions, and lifestyle modifications for comprehensive pain relief.
Patient-Centered Approach
Our patient-centered philosophy means that we prioritize the comfort, preferences, and overall well-being of our patients. We believe in empowering individuals with the knowledge and tools they need to manage their pain effectively. Through education, support, and compassionate care, we help our patients take control of their pain and improve their quality of life.
Real-Life Examples of CureEZ patients.
Savitha's Journey to Pain Relief
Savitha, a 55-year-old woman with type 2 diabetes, had been struggling with severe neuropathic pain in her feet for years. Despite trying various medications, she found little relief and her quality of life was diminishing. After seeking help from CureEZ, Savitha underwent a comprehensive evaluation. Our team developed a personalized care plan that included a combination of gabapentin, physical therapy, and dietary modifications. Additionally, Savitha started regular acupuncture sessions and mindfulness practices. Within months, her pain levels decreased significantly, and she regained her mobility and zest for life.
Gangadhar's Success Story
Gangadhar, a 60-year-old man with a long history of diabetes, suffered from chronic musculoskeletal pain and complications from a foot ulcer. Traditional pain medications provided limited relief, and he faced the prospect of amputation. At CureEZ, we implemented a multifaceted approach to his pain management. Gangadhar's treatment included antidepressants for pain relief, a tailored exercise program, and nutritional supplements to support healing. Complementary therapies like massage and TENS were also introduced. With this comprehensive plan, Gangadhar's pain improved, his ulcer healed, and he avoided amputation, allowing him to continue his daily activities with much less discomfort.
Conclusion
Effective pain management is essential for individuals with diabetes to maintain their quality of life and overall well-being. By understanding the different types of pain associated with diabetes and exploring both pharmacological and non-pharmacological strategies, individuals can find relief and improve their daily functioning. CureEZ is committed to providing comprehensive, personalized pain management solutions, helping patients like Savitha and Gangadhar lead healthier, more comfortable lives. If you are struggling with diabetes-related pain, reach out to CureEZ for a tailored approach to pain relief and experience the difference in quality care.
References
https://diabetes.org/about-diabetes/complications
https://www.mayoclinic.org/diseases-conditions/diabetic-neuropathy/symptoms-causes/syc-20371580
https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/nerve-damage-diabetic-neuropathies
https://www.health.harvard.edu/topics/diabetes
https://www.hopkinsmedicine.org/health/conditions-and-diseases/peripheral-neuropathy
2024.05.30 20:22 HopefulExtent1550 Canada Life PSHCP Diabetic Supplies
So I'm interested in the Freestyle 2 sensors. I'm Type 2, non-Insulin. My Dr has written a prescription for the product. I am shocked at the Pharmacy Price for this product.
So the assistant at Canada Life just read the E-notes associated to Diabetic Supplies and determined it was covered.
I read the Benefits Package and it clearly states Canada Life will not reimburse if you are type 2. They may if you are type 2 and on Insulin.
Has any type 2, non-insulin Diabetic received reimbursement with the PSHCP version of Canada Life?
submitted by HopefulExtent1550 to CanadaPublicServants [link] [comments]
So the assistant at Canada Life just read the E-notes associated to Diabetic Supplies and determined it was covered.
I read the Benefits Package and it clearly states Canada Life will not reimburse if you are type 2. They may if you are type 2 and on Insulin.
Has any type 2, non-insulin Diabetic received reimbursement with the PSHCP version of Canada Life?
2024.05.30 18:42 Standard-Cause-3348 Cerco Noha focus Gambe e focus Upper Back
submitted by Standard-Cause-3348 to FitnesProgramsSharing [link] [comments]
2024.05.30 18:24 thinkingstranger May 29, 2024
President Joe Biden and Vice President Kamala Harris campaigned today in Philadelphia, Pennsylvania. They spoke at Girard College, a school where Black Americans make up most of the student body, where they emphasized the importance of Black voters to the Democratic coalition and the ways in which the administration’s actions have delivered on its promises to the Black community.
“Because Black Americans voted, Kamala and I are President and Vice President of the United States,” Biden said. “That’s not hyperbole. Because you voted, Donald Trump is a defeated former president.”
Harris noted that Black Americans are 60% more likely than white Americans to be diagnosed with diabetes, and called out the administration’s capping of insulin at $35 a month, along with the provisions of the Inflation Reduction Act that permit Medicare to negotiate with pharmaceutical companies. She called out the administration’s relief of more than $165 billion in student loan debt for more than 5 million Americans, as well as the first major bipartisan gun safety law in 30 years.
What has guided them, Harris said to applause, is the “fundamental belief” that “[w]e work for you, the American people, not the special interests, not the billionaires or the big corporations, but the people.”
She contrasted their record with that of former president Trump, who tried to get rid of the Affordable Care Act that puts healthcare within reach for millions of Black Americans, proposed cuts to Social Security and Medicare, and handpicked Supreme Court justices who would overturn Roe v. Wade. “And as he intended, they did,” she said. “[T]oday, one in three women and more than half of Black women of reproductive age live in a state with an abortion ban.”
Then Biden took the stage to chants of “Four more years!” He added to Harris’s list of ways in which the administration has worked for racial equality: reconnecting the Black and brown and poor neighborhoods that were cut apart by highways in the 1960s and addressing the decades of disinvestment that happened as a consequence of the carving up of those neighborhoods (this cutting apart of neighborhoods is a really big deal in urban history, by the way); getting rid of the lead pipes that still contaminate water, especially in minority neighborhoods; making high-speed internet widely available and affordable; investing in historically Black colleges and universities; appointing more Black women to federal circuit courts than all other U.S. presidents combined.
Under the Biden administration, he noted, Black unemployment is at a record low and Black small businesses are starting at the fastest rate in 30 years. The wealth gap between Black Americans and white Americans is the lowest it’s been in 20 years. “We’re opening more doors for economic opportunity, including access to capital, entrepreneurship, workforce training so you can build a life of financial freedom and create generational wealth...all while being the providers and leaders of your families and community,” the president said.
Biden drew a contrast between his administration and Trump, saying, “I’ve shown you who I am, and Trump has shown you who he is. And today, Donald Trump is pandering and peddling lies and stereotypes for your votes so he can win for himself, not for you.” “[W]e’re not going to let Donald Trump turn America into a place that doesn’t believe in honesty, decency, and treating people with respect,” he said, “and I’ll be damned if I’m going to let Donald Trump turn America into a place filled with anger and resentment and hate.”
According to Myah Ward and Brakkton Booker of Politico, this was Biden’s fifth trip to the Philadelphia area and his seventh to Pennsylvania this year. As he tries to win the state in 2024, the campaign has opened 24 field offices and outspent Trump there by a ratio of more than 4 to 1.
Harris and Biden’s appearance in Philadelphia looked pretty much like a normal day in a normal presidential campaign season.
The same was not true of the presumptive Republican presidential nominee Donald Trump, who was in a courtroom in Manhattan as Judge Juan Merchan instructed the jury in the criminal case against Trump for falsifying business records to hide a $130,000 payment to adult film actress Stephanie Clifford, also known as Stormy Daniels, to stop her account of their sexual encounter from becoming public in the days before the 2016 election.
Legal analyst Joyce White Vance explained that to find Trump guilty, “[t]he jury must find unanimously that Trump created fraudulent business records and that he did it with the intent to influence an election through unlawful means.”
Trump and his supporters immediately took to the media to misrepresent the court system. Trump appeared to sleep through the jury instructions but later posted on social media: “I DON’T EVEN KNOW WHAT THE CHARGES ARE IN THIS RIGGED CASE…. THERE IS NO CRIME.” (He had told the judge on April 4, 2023, that he understood the charges against him.) Trump insisted that he had been railroaded by the fact that “a lot of key witnesses were not called,” although his own defense did not call them and he declined to testify himself. He called the judge “conflicted” and “corrupt,” and said “Mother Teresa could not beat these charges,” a reference to the Albanian-Indian Catholic nun canonized by the Catholic Church in 2016.
Fox News host John Roberts misrepresented the judge’s instructions, launching a wave of fury on right-wing media stations and prompting Florida senator Marco Rubio to write: “This is exactly the kind of sham trial used against political opponents of the regime in the old Soviet Union.” Utah senator Mike Lee chimed in with his own attacks on Judge Merchan. Roberts later corrected his tweet, but it was too late to change the narrative.
Tonight, those two themes reappeared again and again on social media in both Trump’s feed and those of his supporters. Their frenzy suggested they are concerned about the jury’s verdict. Newsmax host Todd Starnes tweeted: “President Trump needs to get out of New York City RIGHT NOW! Fly back to Mar-a-Lago or another state that will provide him safe harbor.”
Indeed, it seems we are seeing the fear of accountability that has been missing from the top levels of American politics since President Gerald Ford pardoned President Richard M. Nixon in 1974. While Ford believed Nixon’s accepting the pardon was an admission of guilt for his participation in the coverup of the break-in at the headquarters of the Democratic National Committee in the Watergate Hotel before the 1972 election and anything else he might have done, Nixon never admitted such guilt.
In the fifty years since then, certain powerful people seem to have concluded that they cannot be held accountable to laws or rules. The MAGA Republicans are illustrating that disrespect for the rule of law on a daily basis as they work to undermine the courts and the Department of Justice.
Yesterday, Jodi Kantor of the New York Times reported that Supreme Court Justice Samuel Alito’s story that his wife flew the upside down flag of distress favored by the January 6th rioters as a response to a hostile neighbor did not line up with accounts given by neighbors and a police report.
Because of that distress flag, as well as the “Appeal to Heaven” flag that flew over his beach house, Alito is under increasing pressure to recuse himself from considering cases related to the events of January 6, including whether Trump is immune from prosecution for his actions surrounding the attempt to overturn the results of the 2020 presidential election. Today Alito refused to recuse himself, blaming his wife for flying the flags—“My wife is fond of flying flags. I am not,” he wrote—and suggesting that anyone who thinks he should recuse himself is “motivated by political or ideological considerations.”
And in what should almost certainly be read as trolling those who disagree with him, Alito, the author of the 2022 Dobbs v. Jackson Women’s Health Organization decision taking away from American women the right to make their own decisions about their healthcare, wrote: “[M]y wife is an independently minded private citizen. She makes her own decisions, and I honor her right to do so.”
Trump promptly congratulated Alito “for showing the INTELLIGENCE, COURAGE, and ‘GUTS’ to refuse stepping aside from making a decision on anything January 6th related.”
MAGA attacks on the rule of law affect real people’s lives. Ryan J. Reilly of NBC News reported today that after former Washington, D.C., Metropolitan Police officer Michael Fanone called Trump “authoritarian” with a “violence fetish” in front of the Manhattan courthouse yesterday, Fanone’s 78-year-old mother was swatted, with officers showing up at her home after reports of a murder there. Fanone protected the U.S. Capitol on January 6, 2021, and went into cardiac arrest after a rioter assaulted him with a stun gun. “This is the reality of going up against or challenging Donald Trump…. These swatting calls are incredibly f---ing dangerous, especially when the target is somebody like my mom.”
—
Notes:
https://www.nbcnews.com/politics/justice-department/mother-jan-6-officer-michael-fanone-swatted-called-trump-authoritarian-rcna154467
https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/05/29/remarks-by-president-biden-and-vice-president-harris-at-a-campaign-event-philadelphia-pa/
https://www.politico.com/news/2024/05/29/pennsylvania-2024-biden-trump-00160511
https://www.nytimes.com/2024/05/28/us/justice-alito-neighbors-stop-steal-flag.html
https://www.washingtonpost.com/documents/ae3feb5a-13a4-4f0f-9046-b61a530c40fb.pdf
Civil Discourse with Joyce VanceInstructing a JuryI warned you that this part would be excruciating. The Judge instructed the jury this morning, and they’ve got the case. Their first day of deliberating is finished. They’ve got questions. They’ll return tomorrow for more. This will continue until they either reach a verdict or advise the court that they are hopelessly deadlocked. We are nowhere close t…Read more15 hours ago · 1025 likes · 168 comments · Joyce Vance
X:
toddstarnes/status/1795862269420528012
atrupastatus/1795885918093500699
IsaacDovere/status/1795885752758247564
Acyn/status/1795931517539283004
ProjectLincoln/status/1795863897594904795
johnrobertsFox/status/1795830647719932058
marcorubio/status/1795851071010611529
molcranenewman/status/1795840559653015721
https://x.com/BradMossEsq/status/1795845341402833311
https://x.com/Acyn/status/1795843818061000716
https://x.com/BasedMikeLee/status/1795966214625190351
https://heathercoxrichardson.substack.com/p/may-29-2024
submitted by thinkingstranger to HeatherCoxRichardson [link] [comments]
“Because Black Americans voted, Kamala and I are President and Vice President of the United States,” Biden said. “That’s not hyperbole. Because you voted, Donald Trump is a defeated former president.”
Harris noted that Black Americans are 60% more likely than white Americans to be diagnosed with diabetes, and called out the administration’s capping of insulin at $35 a month, along with the provisions of the Inflation Reduction Act that permit Medicare to negotiate with pharmaceutical companies. She called out the administration’s relief of more than $165 billion in student loan debt for more than 5 million Americans, as well as the first major bipartisan gun safety law in 30 years.
What has guided them, Harris said to applause, is the “fundamental belief” that “[w]e work for you, the American people, not the special interests, not the billionaires or the big corporations, but the people.”
She contrasted their record with that of former president Trump, who tried to get rid of the Affordable Care Act that puts healthcare within reach for millions of Black Americans, proposed cuts to Social Security and Medicare, and handpicked Supreme Court justices who would overturn Roe v. Wade. “And as he intended, they did,” she said. “[T]oday, one in three women and more than half of Black women of reproductive age live in a state with an abortion ban.”
Then Biden took the stage to chants of “Four more years!” He added to Harris’s list of ways in which the administration has worked for racial equality: reconnecting the Black and brown and poor neighborhoods that were cut apart by highways in the 1960s and addressing the decades of disinvestment that happened as a consequence of the carving up of those neighborhoods (this cutting apart of neighborhoods is a really big deal in urban history, by the way); getting rid of the lead pipes that still contaminate water, especially in minority neighborhoods; making high-speed internet widely available and affordable; investing in historically Black colleges and universities; appointing more Black women to federal circuit courts than all other U.S. presidents combined.
Under the Biden administration, he noted, Black unemployment is at a record low and Black small businesses are starting at the fastest rate in 30 years. The wealth gap between Black Americans and white Americans is the lowest it’s been in 20 years. “We’re opening more doors for economic opportunity, including access to capital, entrepreneurship, workforce training so you can build a life of financial freedom and create generational wealth...all while being the providers and leaders of your families and community,” the president said.
Biden drew a contrast between his administration and Trump, saying, “I’ve shown you who I am, and Trump has shown you who he is. And today, Donald Trump is pandering and peddling lies and stereotypes for your votes so he can win for himself, not for you.” “[W]e’re not going to let Donald Trump turn America into a place that doesn’t believe in honesty, decency, and treating people with respect,” he said, “and I’ll be damned if I’m going to let Donald Trump turn America into a place filled with anger and resentment and hate.”
According to Myah Ward and Brakkton Booker of Politico, this was Biden’s fifth trip to the Philadelphia area and his seventh to Pennsylvania this year. As he tries to win the state in 2024, the campaign has opened 24 field offices and outspent Trump there by a ratio of more than 4 to 1.
Harris and Biden’s appearance in Philadelphia looked pretty much like a normal day in a normal presidential campaign season.
The same was not true of the presumptive Republican presidential nominee Donald Trump, who was in a courtroom in Manhattan as Judge Juan Merchan instructed the jury in the criminal case against Trump for falsifying business records to hide a $130,000 payment to adult film actress Stephanie Clifford, also known as Stormy Daniels, to stop her account of their sexual encounter from becoming public in the days before the 2016 election.
Legal analyst Joyce White Vance explained that to find Trump guilty, “[t]he jury must find unanimously that Trump created fraudulent business records and that he did it with the intent to influence an election through unlawful means.”
Trump and his supporters immediately took to the media to misrepresent the court system. Trump appeared to sleep through the jury instructions but later posted on social media: “I DON’T EVEN KNOW WHAT THE CHARGES ARE IN THIS RIGGED CASE…. THERE IS NO CRIME.” (He had told the judge on April 4, 2023, that he understood the charges against him.) Trump insisted that he had been railroaded by the fact that “a lot of key witnesses were not called,” although his own defense did not call them and he declined to testify himself. He called the judge “conflicted” and “corrupt,” and said “Mother Teresa could not beat these charges,” a reference to the Albanian-Indian Catholic nun canonized by the Catholic Church in 2016.
Fox News host John Roberts misrepresented the judge’s instructions, launching a wave of fury on right-wing media stations and prompting Florida senator Marco Rubio to write: “This is exactly the kind of sham trial used against political opponents of the regime in the old Soviet Union.” Utah senator Mike Lee chimed in with his own attacks on Judge Merchan. Roberts later corrected his tweet, but it was too late to change the narrative.
Tonight, those two themes reappeared again and again on social media in both Trump’s feed and those of his supporters. Their frenzy suggested they are concerned about the jury’s verdict. Newsmax host Todd Starnes tweeted: “President Trump needs to get out of New York City RIGHT NOW! Fly back to Mar-a-Lago or another state that will provide him safe harbor.”
Indeed, it seems we are seeing the fear of accountability that has been missing from the top levels of American politics since President Gerald Ford pardoned President Richard M. Nixon in 1974. While Ford believed Nixon’s accepting the pardon was an admission of guilt for his participation in the coverup of the break-in at the headquarters of the Democratic National Committee in the Watergate Hotel before the 1972 election and anything else he might have done, Nixon never admitted such guilt.
In the fifty years since then, certain powerful people seem to have concluded that they cannot be held accountable to laws or rules. The MAGA Republicans are illustrating that disrespect for the rule of law on a daily basis as they work to undermine the courts and the Department of Justice.
Yesterday, Jodi Kantor of the New York Times reported that Supreme Court Justice Samuel Alito’s story that his wife flew the upside down flag of distress favored by the January 6th rioters as a response to a hostile neighbor did not line up with accounts given by neighbors and a police report.
Because of that distress flag, as well as the “Appeal to Heaven” flag that flew over his beach house, Alito is under increasing pressure to recuse himself from considering cases related to the events of January 6, including whether Trump is immune from prosecution for his actions surrounding the attempt to overturn the results of the 2020 presidential election. Today Alito refused to recuse himself, blaming his wife for flying the flags—“My wife is fond of flying flags. I am not,” he wrote—and suggesting that anyone who thinks he should recuse himself is “motivated by political or ideological considerations.”
And in what should almost certainly be read as trolling those who disagree with him, Alito, the author of the 2022 Dobbs v. Jackson Women’s Health Organization decision taking away from American women the right to make their own decisions about their healthcare, wrote: “[M]y wife is an independently minded private citizen. She makes her own decisions, and I honor her right to do so.”
Trump promptly congratulated Alito “for showing the INTELLIGENCE, COURAGE, and ‘GUTS’ to refuse stepping aside from making a decision on anything January 6th related.”
MAGA attacks on the rule of law affect real people’s lives. Ryan J. Reilly of NBC News reported today that after former Washington, D.C., Metropolitan Police officer Michael Fanone called Trump “authoritarian” with a “violence fetish” in front of the Manhattan courthouse yesterday, Fanone’s 78-year-old mother was swatted, with officers showing up at her home after reports of a murder there. Fanone protected the U.S. Capitol on January 6, 2021, and went into cardiac arrest after a rioter assaulted him with a stun gun. “This is the reality of going up against or challenging Donald Trump…. These swatting calls are incredibly f---ing dangerous, especially when the target is somebody like my mom.”
—
Notes:
https://www.nbcnews.com/politics/justice-department/mother-jan-6-officer-michael-fanone-swatted-called-trump-authoritarian-rcna154467
https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/05/29/remarks-by-president-biden-and-vice-president-harris-at-a-campaign-event-philadelphia-pa/
https://www.politico.com/news/2024/05/29/pennsylvania-2024-biden-trump-00160511
https://www.nytimes.com/2024/05/28/us/justice-alito-neighbors-stop-steal-flag.html
https://www.washingtonpost.com/documents/ae3feb5a-13a4-4f0f-9046-b61a530c40fb.pdf
Civil Discourse with Joyce VanceInstructing a JuryI warned you that this part would be excruciating. The Judge instructed the jury this morning, and they’ve got the case. Their first day of deliberating is finished. They’ve got questions. They’ll return tomorrow for more. This will continue until they either reach a verdict or advise the court that they are hopelessly deadlocked. We are nowhere close t…Read more15 hours ago · 1025 likes · 168 comments · Joyce Vance
X:
toddstarnes/status/1795862269420528012
atrupastatus/1795885918093500699
IsaacDovere/status/1795885752758247564
Acyn/status/1795931517539283004
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johnrobertsFox/status/1795830647719932058
marcorubio/status/1795851071010611529
molcranenewman/status/1795840559653015721
https://x.com/BradMossEsq/status/1795845341402833311
https://x.com/Acyn/status/1795843818061000716
https://x.com/BasedMikeLee/status/1795966214625190351
https://heathercoxrichardson.substack.com/p/may-29-2024
2024.05.30 18:23 thinkingstranger May 29, 2024
President Joe Biden and Vice President Kamala Harris campaigned today in Philadelphia, Pennsylvania. They spoke at Girard College, a school where Black Americans make up most of the student body, where they emphasized the importance of Black voters to the Democratic coalition and the ways in which the administration’s actions have delivered on its promises to the Black community.
“Because Black Americans voted, Kamala and I are President and Vice President of the United States,” Biden said. “That’s not hyperbole. Because you voted, Donald Trump is a defeated former president.”
Harris noted that Black Americans are 60% more likely than white Americans to be diagnosed with diabetes, and called out the administration’s capping of insulin at $35 a month, along with the provisions of the Inflation Reduction Act that permit Medicare to negotiate with pharmaceutical companies. She called out the administration’s relief of more than $165 billion in student loan debt for more than 5 million Americans, as well as the first major bipartisan gun safety law in 30 years.
What has guided them, Harris said to applause, is the “fundamental belief” that “[w]e work for you, the American people, not the special interests, not the billionaires or the big corporations, but the people.”
She contrasted their record with that of former president Trump, who tried to get rid of the Affordable Care Act that puts healthcare within reach for millions of Black Americans, proposed cuts to Social Security and Medicare, and handpicked Supreme Court justices who would overturn Roe v. Wade. “And as he intended, they did,” she said. “[T]oday, one in three women and more than half of Black women of reproductive age live in a state with an abortion ban.”
Then Biden took the stage to chants of “Four more years!” He added to Harris’s list of ways in which the administration has worked for racial equality: reconnecting the Black and brown and poor neighborhoods that were cut apart by highways in the 1960s and addressing the decades of disinvestment that happened as a consequence of the carving up of those neighborhoods (this cutting apart of neighborhoods is a really big deal in urban history, by the way); getting rid of the lead pipes that still contaminate water, especially in minority neighborhoods; making high-speed internet widely available and affordable; investing in historically Black colleges and universities; appointing more Black women to federal circuit courts than all other U.S. presidents combined.
Under the Biden administration, he noted, Black unemployment is at a record low and Black small businesses are starting at the fastest rate in 30 years. The wealth gap between Black Americans and white Americans is the lowest it’s been in 20 years. “We’re opening more doors for economic opportunity, including access to capital, entrepreneurship, workforce training so you can build a life of financial freedom and create generational wealth...all while being the providers and leaders of your families and community,” the president said.
Biden drew a contrast between his administration and Trump, saying, “I’ve shown you who I am, and Trump has shown you who he is. And today, Donald Trump is pandering and peddling lies and stereotypes for your votes so he can win for himself, not for you.” “[W]e’re not going to let Donald Trump turn America into a place that doesn’t believe in honesty, decency, and treating people with respect,” he said, “and I’ll be damned if I’m going to let Donald Trump turn America into a place filled with anger and resentment and hate.”
According to Myah Ward and Brakkton Booker of Politico, this was Biden’s fifth trip to the Philadelphia area and his seventh to Pennsylvania this year. As he tries to win the state in 2024, the campaign has opened 24 field offices and outspent Trump there by a ratio of more than 4 to 1.
Harris and Biden’s appearance in Philadelphia looked pretty much like a normal day in a normal presidential campaign season.
The same was not true of the presumptive Republican presidential nominee Donald Trump, who was in a courtroom in Manhattan as Judge Juan Merchan instructed the jury in the criminal case against Trump for falsifying business records to hide a $130,000 payment to adult film actress Stephanie Clifford, also known as Stormy Daniels, to stop her account of their sexual encounter from becoming public in the days before the 2016 election.
Legal analyst Joyce White Vance explained that to find Trump guilty, “[t]he jury must find unanimously that Trump created fraudulent business records and that he did it with the intent to influence an election through unlawful means.”
Trump and his supporters immediately took to the media to misrepresent the court system. Trump appeared to sleep through the jury instructions but later posted on social media: “I DON’T EVEN KNOW WHAT THE CHARGES ARE IN THIS RIGGED CASE…. THERE IS NO CRIME.” (He had told the judge on April 4, 2023, that he understood the charges against him.) Trump insisted that he had been railroaded by the fact that “a lot of key witnesses were not called,” although his own defense did not call them and he declined to testify himself. He called the judge “conflicted” and “corrupt,” and said “Mother Teresa could not beat these charges,” a reference to the Albanian-Indian Catholic nun canonized by the Catholic Church in 2016.
Fox News host John Roberts misrepresented the judge’s instructions, launching a wave of fury on right-wing media stations and prompting Florida senator Marco Rubio to write: “This is exactly the kind of sham trial used against political opponents of the regime in the old Soviet Union.” Utah senator Mike Lee chimed in with his own attacks on Judge Merchan. Roberts later corrected his tweet, but it was too late to change the narrative.
Tonight, those two themes reappeared again and again on social media in both Trump’s feed and those of his supporters. Their frenzy suggested they are concerned about the jury’s verdict. Newsmax host Todd Starnes tweeted: “President Trump needs to get out of New York City RIGHT NOW! Fly back to Mar-a-Lago or another state that will provide him safe harbor.”
Indeed, it seems we are seeing the fear of accountability that has been missing from the top levels of American politics since President Gerald Ford pardoned President Richard M. Nixon in 1974. While Ford believed Nixon’s accepting the pardon was an admission of guilt for his participation in the coverup of the break-in at the headquarters of the Democratic National Committee in the Watergate Hotel before the 1972 election and anything else he might have done, Nixon never admitted such guilt.
In the fifty years since then, certain powerful people seem to have concluded that they cannot be held accountable to laws or rules. The MAGA Republicans are illustrating that disrespect for the rule of law on a daily basis as they work to undermine the courts and the Department of Justice.
Yesterday, Jodi Kantor of the New York Times reported that Supreme Court Justice Samuel Alito’s story that his wife flew the upside down flag of distress favored by the January 6th rioters as a response to a hostile neighbor did not line up with accounts given by neighbors and a police report.
Because of that distress flag, as well as the “Appeal to Heaven” flag that flew over his beach house, Alito is under increasing pressure to recuse himself from considering cases related to the events of January 6, including whether Trump is immune from prosecution for his actions surrounding the attempt to overturn the results of the 2020 presidential election. Today Alito refused to recuse himself, blaming his wife for flying the flags—“My wife is fond of flying flags. I am not,” he wrote—and suggesting that anyone who thinks he should recuse himself is “motivated by political or ideological considerations.”
And in what should almost certainly be read as trolling those who disagree with him, Alito, the author of the 2022 Dobbs v. Jackson Women’s Health Organization decision taking away from American women the right to make their own decisions about their healthcare, wrote: “[M]y wife is an independently minded private citizen. She makes her own decisions, and I honor her right to do so.”
Trump promptly congratulated Alito “for showing the INTELLIGENCE, COURAGE, and ‘GUTS’ to refuse stepping aside from making a decision on anything January 6th related.”
MAGA attacks on the rule of law affect real people’s lives. Ryan J. Reilly of NBC News reported today that after former Washington, D.C., Metropolitan Police officer Michael Fanone called Trump “authoritarian” with a “violence fetish” in front of the Manhattan courthouse yesterday, Fanone’s 78-year-old mother was swatted, with officers showing up at her home after reports of a murder there. Fanone protected the U.S. Capitol on January 6, 2021, and went into cardiac arrest after a rioter assaulted him with a stun gun. “This is the reality of going up against or challenging Donald Trump…. These swatting calls are incredibly f---ing dangerous, especially when the target is somebody like my mom.”
—
Notes:
https://www.nbcnews.com/politics/justice-department/mother-jan-6-officer-michael-fanone-swatted-called-trump-authoritarian-rcna154467
https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/05/29/remarks-by-president-biden-and-vice-president-harris-at-a-campaign-event-philadelphia-pa/
https://www.politico.com/news/2024/05/29/pennsylvania-2024-biden-trump-00160511
https://www.nytimes.com/2024/05/28/us/justice-alito-neighbors-stop-steal-flag.html
https://www.washingtonpost.com/documents/ae3feb5a-13a4-4f0f-9046-b61a530c40fb.pdf
Civil Discourse with Joyce VanceInstructing a JuryI warned you that this part would be excruciating. The Judge instructed the jury this morning, and they’ve got the case. Their first day of deliberating is finished. They’ve got questions. They’ll return tomorrow for more. This will continue until they either reach a verdict or advise the court that they are hopelessly deadlocked. We are nowhere close t…Read more15 hours ago · 1025 likes · 168 comments · Joyce Vance
X:
toddstarnes/status/1795862269420528012
atrupastatus/1795885918093500699
IsaacDovere/status/1795885752758247564
Acyn/status/1795931517539283004
ProjectLincoln/status/1795863897594904795
johnrobertsFox/status/1795830647719932058
marcorubio/status/1795851071010611529
molcranenewman/status/1795840559653015721
https://x.com/BradMossEsq/status/1795845341402833311
https://x.com/Acyn/status/1795843818061000716
https://x.com/BasedMikeLee/status/1795966214625190351
https://heathercoxrichardson.substack.com/p/may-29-2024
submitted by thinkingstranger to HeatherCoxRichardson [link] [comments]
“Because Black Americans voted, Kamala and I are President and Vice President of the United States,” Biden said. “That’s not hyperbole. Because you voted, Donald Trump is a defeated former president.”
Harris noted that Black Americans are 60% more likely than white Americans to be diagnosed with diabetes, and called out the administration’s capping of insulin at $35 a month, along with the provisions of the Inflation Reduction Act that permit Medicare to negotiate with pharmaceutical companies. She called out the administration’s relief of more than $165 billion in student loan debt for more than 5 million Americans, as well as the first major bipartisan gun safety law in 30 years.
What has guided them, Harris said to applause, is the “fundamental belief” that “[w]e work for you, the American people, not the special interests, not the billionaires or the big corporations, but the people.”
She contrasted their record with that of former president Trump, who tried to get rid of the Affordable Care Act that puts healthcare within reach for millions of Black Americans, proposed cuts to Social Security and Medicare, and handpicked Supreme Court justices who would overturn Roe v. Wade. “And as he intended, they did,” she said. “[T]oday, one in three women and more than half of Black women of reproductive age live in a state with an abortion ban.”
Then Biden took the stage to chants of “Four more years!” He added to Harris’s list of ways in which the administration has worked for racial equality: reconnecting the Black and brown and poor neighborhoods that were cut apart by highways in the 1960s and addressing the decades of disinvestment that happened as a consequence of the carving up of those neighborhoods (this cutting apart of neighborhoods is a really big deal in urban history, by the way); getting rid of the lead pipes that still contaminate water, especially in minority neighborhoods; making high-speed internet widely available and affordable; investing in historically Black colleges and universities; appointing more Black women to federal circuit courts than all other U.S. presidents combined.
Under the Biden administration, he noted, Black unemployment is at a record low and Black small businesses are starting at the fastest rate in 30 years. The wealth gap between Black Americans and white Americans is the lowest it’s been in 20 years. “We’re opening more doors for economic opportunity, including access to capital, entrepreneurship, workforce training so you can build a life of financial freedom and create generational wealth...all while being the providers and leaders of your families and community,” the president said.
Biden drew a contrast between his administration and Trump, saying, “I’ve shown you who I am, and Trump has shown you who he is. And today, Donald Trump is pandering and peddling lies and stereotypes for your votes so he can win for himself, not for you.” “[W]e’re not going to let Donald Trump turn America into a place that doesn’t believe in honesty, decency, and treating people with respect,” he said, “and I’ll be damned if I’m going to let Donald Trump turn America into a place filled with anger and resentment and hate.”
According to Myah Ward and Brakkton Booker of Politico, this was Biden’s fifth trip to the Philadelphia area and his seventh to Pennsylvania this year. As he tries to win the state in 2024, the campaign has opened 24 field offices and outspent Trump there by a ratio of more than 4 to 1.
Harris and Biden’s appearance in Philadelphia looked pretty much like a normal day in a normal presidential campaign season.
The same was not true of the presumptive Republican presidential nominee Donald Trump, who was in a courtroom in Manhattan as Judge Juan Merchan instructed the jury in the criminal case against Trump for falsifying business records to hide a $130,000 payment to adult film actress Stephanie Clifford, also known as Stormy Daniels, to stop her account of their sexual encounter from becoming public in the days before the 2016 election.
Legal analyst Joyce White Vance explained that to find Trump guilty, “[t]he jury must find unanimously that Trump created fraudulent business records and that he did it with the intent to influence an election through unlawful means.”
Trump and his supporters immediately took to the media to misrepresent the court system. Trump appeared to sleep through the jury instructions but later posted on social media: “I DON’T EVEN KNOW WHAT THE CHARGES ARE IN THIS RIGGED CASE…. THERE IS NO CRIME.” (He had told the judge on April 4, 2023, that he understood the charges against him.) Trump insisted that he had been railroaded by the fact that “a lot of key witnesses were not called,” although his own defense did not call them and he declined to testify himself. He called the judge “conflicted” and “corrupt,” and said “Mother Teresa could not beat these charges,” a reference to the Albanian-Indian Catholic nun canonized by the Catholic Church in 2016.
Fox News host John Roberts misrepresented the judge’s instructions, launching a wave of fury on right-wing media stations and prompting Florida senator Marco Rubio to write: “This is exactly the kind of sham trial used against political opponents of the regime in the old Soviet Union.” Utah senator Mike Lee chimed in with his own attacks on Judge Merchan. Roberts later corrected his tweet, but it was too late to change the narrative.
Tonight, those two themes reappeared again and again on social media in both Trump’s feed and those of his supporters. Their frenzy suggested they are concerned about the jury’s verdict. Newsmax host Todd Starnes tweeted: “President Trump needs to get out of New York City RIGHT NOW! Fly back to Mar-a-Lago or another state that will provide him safe harbor.”
Indeed, it seems we are seeing the fear of accountability that has been missing from the top levels of American politics since President Gerald Ford pardoned President Richard M. Nixon in 1974. While Ford believed Nixon’s accepting the pardon was an admission of guilt for his participation in the coverup of the break-in at the headquarters of the Democratic National Committee in the Watergate Hotel before the 1972 election and anything else he might have done, Nixon never admitted such guilt.
In the fifty years since then, certain powerful people seem to have concluded that they cannot be held accountable to laws or rules. The MAGA Republicans are illustrating that disrespect for the rule of law on a daily basis as they work to undermine the courts and the Department of Justice.
Yesterday, Jodi Kantor of the New York Times reported that Supreme Court Justice Samuel Alito’s story that his wife flew the upside down flag of distress favored by the January 6th rioters as a response to a hostile neighbor did not line up with accounts given by neighbors and a police report.
Because of that distress flag, as well as the “Appeal to Heaven” flag that flew over his beach house, Alito is under increasing pressure to recuse himself from considering cases related to the events of January 6, including whether Trump is immune from prosecution for his actions surrounding the attempt to overturn the results of the 2020 presidential election. Today Alito refused to recuse himself, blaming his wife for flying the flags—“My wife is fond of flying flags. I am not,” he wrote—and suggesting that anyone who thinks he should recuse himself is “motivated by political or ideological considerations.”
And in what should almost certainly be read as trolling those who disagree with him, Alito, the author of the 2022 Dobbs v. Jackson Women’s Health Organization decision taking away from American women the right to make their own decisions about their healthcare, wrote: “[M]y wife is an independently minded private citizen. She makes her own decisions, and I honor her right to do so.”
Trump promptly congratulated Alito “for showing the INTELLIGENCE, COURAGE, and ‘GUTS’ to refuse stepping aside from making a decision on anything January 6th related.”
MAGA attacks on the rule of law affect real people’s lives. Ryan J. Reilly of NBC News reported today that after former Washington, D.C., Metropolitan Police officer Michael Fanone called Trump “authoritarian” with a “violence fetish” in front of the Manhattan courthouse yesterday, Fanone’s 78-year-old mother was swatted, with officers showing up at her home after reports of a murder there. Fanone protected the U.S. Capitol on January 6, 2021, and went into cardiac arrest after a rioter assaulted him with a stun gun. “This is the reality of going up against or challenging Donald Trump…. These swatting calls are incredibly f---ing dangerous, especially when the target is somebody like my mom.”
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Notes:
https://www.nbcnews.com/politics/justice-department/mother-jan-6-officer-michael-fanone-swatted-called-trump-authoritarian-rcna154467
https://www.whitehouse.gov/briefing-room/speeches-remarks/2024/05/29/remarks-by-president-biden-and-vice-president-harris-at-a-campaign-event-philadelphia-pa/
https://www.politico.com/news/2024/05/29/pennsylvania-2024-biden-trump-00160511
https://www.nytimes.com/2024/05/28/us/justice-alito-neighbors-stop-steal-flag.html
https://www.washingtonpost.com/documents/ae3feb5a-13a4-4f0f-9046-b61a530c40fb.pdf
Civil Discourse with Joyce VanceInstructing a JuryI warned you that this part would be excruciating. The Judge instructed the jury this morning, and they’ve got the case. Their first day of deliberating is finished. They’ve got questions. They’ll return tomorrow for more. This will continue until they either reach a verdict or advise the court that they are hopelessly deadlocked. We are nowhere close t…Read more15 hours ago · 1025 likes · 168 comments · Joyce Vance
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