Cell analogies church

For All Things Creepy

2009.10.20 21:01 ContentWithOurDecay For All Things Creepy

All things creepy! (excluding Spez)
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2009.06.02 12:17 bimomib Live better longer.

Reasons to hope to see the age of 100 and beyond: Biomedical rejuvenation through damage repair, manipulation of metabolism, beyond the mere results of exercise, caloric restriction, and fasting. Stem cell therapies, anti-cancer viruses, gene therapy, senolytics, and whatever is coming next... /longevity is the place to find all information about new longevity, healthspan, happyspan, and rejuvenation research related news.
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2024.06.01 13:34 keleko67 Amp decision time - What to do with Fender Super Champ x2 and Katana 100 mk2

I don’t feel satisfied with my current amps. As the subject says I have those two amps now. I mostly use the Fender at church and the Katana at home. However, the power situation at church is less than optimal, and the Super Champ is a bit sensitive to that. Also it hasn’t been possible to make use of the modeling ability for years since the software was discontinued. The Katana is quite nice, of course, but I’m not really using the modeling aspect of it. Instead I have a multi-effects pedal (NUX MG-400) that has more flexibility than the Katana. The NUX has more memory slots, for example. I’m not going to go into which is better here since I’ve pretty much decided it works better for me this way.
I like to leave the Fender at church most of the time just to spare the lugging back and forth. But, I can’t really dial in a sound at home when I do that. I don’t really have a good space to keep it at home all the time, either.
So my decision is what to do with these two amps.
My current line of thinking is to trade both in and get two of the same, or close to same, amps so I can have one at home and one at church. That way I can get a sound I like at home and easily replicate at church. Having the multi pedal helps with that, and is much less cumbersome to carry. My local used shop has a few Orange Crush Pro 60s and a 35RT. I was considering getting one of each, with the 35RT for home and 60 for church. I also like the analog signal line on the Crush amps.
I could also see getting another Katana to leave at church. However, that feels less optimal to me given I don’t use the modeling of the amp itself. The 100 is also a bit cramped at home due to space limitations. If they made a 50 with fx loop, that’d be an easier decision. Both the Orange models do all I want, and the 35RT would fit better at home.
Am I crazy for wanting to trade in the Fender and Katana for a medium and large Crush? Something else I should consider instead? I do prefer solid state over tube (don’t judge me, please), so suggestions in that category would be useful.
submitted by keleko67 to GuitarAmps [link] [comments]


2024.06.01 11:58 Kaslight What's actually going on in FF7R (The Whispers [Probably] Got You)

EXTENSIVE Rebirth, Remake, and OG FF7 spoilers in here.
This is a continuation of What's Actually Going On in FF7R (The White Materia) where I attempt to make sense of everything the Remake continuity added to the OG FF7 story. It really is best if you read the other thread first, just because this will be easier if i've already explained my theory on the White Materia and it's associated spell, Holy.
Another disclaimer : This is, still, just a theory, aGameTheory. Don't hate me (or square?) in the event it's completely wrong, which it has a decent chance of being.
There are only 2 things about FF7's Story that have fundamentally changed in Remake.
The White and Black Materia. Or more specifically, the Magic granted by them.
But what I want to discuss this time is (what I personally think, as of Rebirth) is one brilliant misdirection from Square Enix...in hindsight, anyway.

The Whispers

Oh no
"....What the hell was Square thinking?" -- You, probably, watching the ending to Rebirth and/or Remake
Well, they were thinking exactly what you were thinking. And they used it against you.
So getting right to it. TLDR;
The Whispers are exactly what they were said to be -- they protect fate by rejecting any changes to the Lifestream. The misdirection here is how YOU have been goaded into misinterpreting this information.
The White and Black Materia can fully explain their existence and purpose. And it has absolutely NOTHING to do with the OG FF7.
Let's start with what we learned from the previous thread about the White Materia:
So what does the White Materia ACTUALLY do in FF7R?
The White Materia (Holy) gives the user access to the Lifestream. Not just a piece of its knowledge, like regular materia....but the actual lifestream itself. In doing so, they gain knowledge, like all Materia allows them to do. Knowledge of the past, the future, and everything else in flux.
But this is NOT knowledge that you're not supposed to be able to actually do anything with, **because unlike casting Fire or Lightning....**knowing the future allows you to change fate.
Materia are orbs containing knowledge of the ancients. In effect, they contain information from the lifestream itself. The White Materia's magic (Holy) is special though. The magic it contains seems to allow the user to traverse the lifestream itself. This means, in effect, the ability to interact with (and take knowledge from) the actual memories of the Lifestream.
As we know, the Lifestream is everything, everywhere, and every time. All life comes from the lifestream, and when something dies, it returns there. And its memories stay there forever, as physical places within the lifestream.
This is something Tifa observed for herself in Rebirth. In her brief time floating with the WEAPON, she was reunited with her very own memories...in a very literal fashion.
Tifa, inside the Lifestream in the middle of the Gongaga Reactor
This is the Mako pool in the Lifestream underneath Gongaga. We literally watched Tifa fall in, and physically swim to this location........so why is Tifa's house here? Along with...the Nibelheim Mountians?
A Fragmented Nibelheim, including Mt Nibel and the Bridge that Tifa and Cloud almost died on in the past.
Tifa's memories are not only being played out here....they are physically real. This is because she's inside the Lifestream. She hasn't gone anywhere, she's still in Gongaga, but look at the extent to which this pool of Mako is able to interact with one person's memories.
And also....wait a second.
This space beneath the reactor is filled with White and Black Whispers.
...I thought we killed all the whispers? What are they doing here?
We'll come back to this later.
Lets back up a bit.

Why you [probably] hated the Whispers.

Hear me out.
The "OG Storyline" has never existed in Remake. It's not a thing. And the Whispers have nothing to do with it.
\"Oh, the Whispers came because Reno doesn't die in the original game\" -- You, probably
"The whispers were put into the game as a meta commentary on how the developers just want to create their own story, but the fans won't let us, so the party fucking KILLS FATE so that Nomura or Nojima or whomever is most annoying can write whatever they want." -- The Internet. Also you. Probably.
Everyone thinks the Whispers only existed in Remake in order to ensure that the story never deviates from the OG FF7 Storyline. Every time something important is about to happen that didn't happen in the original game, the whispers intervene and correct the timeline.
This is the typical, widely accepted "Meta Commentary" explanation of the Whispers.
But it's wrong.
No, not just because this theory says so. This interpretation was ALWAYS wrong.
So the whispers are canon police, but are just gonna IGNORE stuff like this?
FF7R's storyline is self-contained. If the whispers existed to "protect the old events", then why is even Remake chocked full of shit that never happened in the OG and would actively change the story if it did?
But don't be confused -- the writers ABSOLUTELY wanted you to think this way. It's what bothered me about Remake's ending. But they were actually clever about it, and Rebirth vindicates this decision.
"Changing the Future", "Defying Fate", and "The Future is Unwritten" has nothing to do the OG FF7.
Okay good we got this out of the way, I can stop talking about Meta Analysis and get to the actual good stuff.

What the whispers were ACTUALLY doing

Remake explained what the Whispers are verbatim.
They protect fate -- the Lifestream. From Aerith, and Jenova.
The Lifestream IS Fate.
Red -"Perhaps best described as arbiters of fate. They are drawn to those who attempt to alter destiny's course and ensure they do not."
Tifa - "And you're saying that flow is somehow...fixed?
Red - "Yes. For it is the will of the planet itself."
Barret then speaks about possible bad fates. And Red XIII says this:
Barret - "So if we're destined for a bleak future, these Whispers will try to keep us on that course?"
"....Now wait just a damn minute. How in the hell could you possibly know any of that? Spouting that cryptic stuff -- which could all be bullshit!"
Red - "When Aerith reached out to me...I found this knowledge of the Whispers."
In the previous thread, we explained how Aerith has been messing with the Lifestream by mistakenly using the White Materia to obtain information she has no business knowing. The Whispers are simply reacting to her blatant misuse of this, and act to correct it.
This is very consistent, even in Pt1. The Whispers in Remake ONLY appear when someone is either:
  1. Using forbidden knowledge from the Lifestream
  2. Manipulating events by sharing forbidden knowledge from the lifestream
  3. When something foreign attempts to force its will on the lifestream
This is the only time they act. But the THIRD one is the most important. I'm going to go through a few examples in Remake and show exactly what's happening that is causing the Whispers to intervene, and explicitly why.
After I show you this, please go back and watch videos of all these sorts of events in Remake. You will see exactly what I mean.
Okay, buckle up kids!

Violation #1 Using forbidden knowledge from the Lifestream

Watching the first appearance of Aerith in Remake gives us full clarity of what's actually happening.
Aerith is attacked by an invisible force.
Aerith is being attacked by Whispers. This is because she possesses the White Materia, and has constant access to knowledge she isn't supposed to have. They are taking it from her.
Thing to note here. Cloud cannot see the whispers. This is because he is not violating any of the 3 rules.
Sephiroth makes an appearance here.
The appearance of the \"Mental Static\" used in both Remake and Rebirth
This is a Red Herring...in fact, this is THREE brilliantly placed Red Herrings. Because the "Memory Static" that appears here belongs to both Cloud AND Aerith, and serves to confuse you on what it actually means.
  1. Aerith sees Cloud, and immediately gains knowledge about them both that she is not supposed to know. Also, if you pay attention, Aerith is NOT frozen during this sequence. This is her scene just as much as it is Cloud's.
  2. Cloud has yet another vision of Sephiroth, caused by his Jenova cells. This is a huge misdirection, to eventually make you think Sephiroth is popping up in places he "shouldn't be."
  3. This is where Remake starts to fuck with your head. They're using the same memory effect for two different characters, for two different reasons. But the result is essentially the same -- the characters involved are having their perception altered. Remake does NOT distinguish between static caused by Holy or static caused by Jenova. They are treated equally in Remake.
The biggest red herring here though is Sephiroth.
It SEEMS unnatural that Sephiroth is appearing here, this early in the game. But it isn't unnatural -- Cloud is plagued by these visions all the time in this continuity. This is why the game gave us a Sephiroth appearance immediately after the Bombing Mission.
Now. Notice how, despite being attacked by invisible whispers, Aerith mostly seems unbothered by this.
...Almost as if she's used to it. Similar to the way Cloud is equally used to visions of Sephiroth. They BOTH carry on with the conversation as though NOTHING has happened.
The game is explicitly showing you that both of these occurrences are seen as normal for these characters. Suggesting that they have actually been dealing with them for much longer than you would think.
Aerith has another Whisper attack. Cloud is once again very confused, until this happens:
Cloud's violation of #1 through contact with Aerith
Aerith touches Cloud.
We learn later that Aerith touching you gives you knowledge you're not supposed to have. Thus, Cloud is now in violation of Rule #1 -- Forbidden Knowledge. He can now observe whispers for the rest of the story.

Violation #2 Manipulating events by sharing forbidden knowledge from the lifestream

The Church Scene is a great example of this. In fact, most of the moments in Rebirth involve Aerith doing this to some degree.
The White Materia is explicitly the cause of the Whisper Attack in the church, and the game goes out of its way to make it very obvious.
Cloud Memory Static, this time it's Holy, not Jenova. (I don't have enough attachments to spell this out, so please go look at the scene after you read this.)
This is another VERY good example of Remake fucking with your head.
The Red Herring here is obvious -- the vision of Aerith's Death. Yes, it was a vision of her death. But her death wasn't the important information the game was showing you in this scene. The White Materia was.
Regardless, the whispers did not intervene here, despite Cloud obviously glimpsing forbidden knowledge.
So why DID they intervene?
\"...Huh?\" - Cloud
Because Aerith couldn't keep her mouth shut.
  1. She tells Reno that Cloud is her bodyguard. He isn't. Reno is.
  2. She exposed that he was a Soldier. Reno explicitly does not like Soldiers.
  3. She already knew that Cloud was doing mercenary work, and used this to persuade him.
Cloud told her none of this information. But it caught Reno's attention. And what was the result?
*Sizes Cloud up*
"Well, you're weird enough to be one."
\"What Class are you?\"
Reno doubts Cloud's Identity as a First Class Ex-Soldier. And Cloud violently reacts to protect it.
The whispers stopped Cloud from killing Reno, NOT because Reno survives in the OG game...but because Reno's life wouldn't even be at risk here if Aerith didn't instigate this fight.
And just like the Flower scene, Remake actually sets this one up with prior character information too. -- Cloud was shown from the beginning of the game to be prone to extreme violence. He would have also executed Johnny without Tifa's intervention. So we KNOW he would have killed Reno if the Whispers didn't intervene.
Hopefully you're beginning to see a pattern here.
Here is the most obvious example of this rule triggering the Whispers.
Aerith attempting to stop Barret from doing something....
In this scene, we see Aerith clearly knows something she isn't supposed to. She wants to share with Barret that killing the President isn't a good idea...And the whispers immediately appear, threatening her to stop. By this point, Aerith is beginning to become aware of why the whispers are harassing her so much.
I covered this scene in my last post, so I wont again...but this scene is crucial towards understanding what's happening in this game. Everyone should watch this scene again. Pay attention to what happens to Aerith the moment she says "Follow the Yellow Flowers". Aerith is clearly not herself as she says this. It's almost as if someone possessed her to say it. And the Whispers absolutely swarm her as a result.

Violation #3 -- When something foreign attempts to force its will on the lifestream

And here we go. The one that caused like 90% of the confusion in Remake. To be fair, this could only really be understood in hindsight after playing Rebirth.
There are many cases in Remake where the Whispers do something that seems...odd, given their explanations as arbiters of fate. Like attacking Sector 7, silencing Hojo, or literally helping Sephiroth at the end of the game. This is because although it's clearly whispers doing it...in Remake there is no visual indication of which Will any given Whispers serve -- The Planet, or Jenova's.
They all LOOK the same.
But they absolutely ARE NOT the same -- they are separate (black and white), just like in Rebirth.
But Remake included subtle clues as a nod to this reveal in Rebirth.
The Whisper Attack on Sector 7
This is another situation where you're expected to believe that the whispers are causing a ruckus because Cloud isn't going on the second bombing mission with Avalanche. Which is something we know he does in the OG game.
But that's just because we likely misinterpreted the clues that lead up to this moment that explain exactly why this is happening : The white whispers are attempting to correct the deliberate isolation of the main party by the black whispers.
A whisper is seen lurking around in Sector 7 the day before this happens. It's extremely easy to miss.
A whisper was present in Seventh Heaven. This was shown immediately after Barret told Cloud he wasn't on the next mission and has to leave.
See...if you're comparing Remake to the OG, then this whisper shown here is 100% going to force you to misinterpret what it's doing here.
In Seventh Heaven, multiple things happen that result in a break up of the entire main party.
  1. Tifa is feeling anxious about the next mission. Jesse goes out of her way to voice concerns about her involvement, leading to her getting kicked off the team for the mission.
  2. Jesse then tries to aim to get Cloud placed on the team instead. Barret refuses to do this because he "doesn't want the team leaning on him."
  3. Barret pays Cloud, tells him he isn't wanted on the next mission, and kicks him out the bar.
  4. A whisper will literally stop you from entering Seventh Heaven again after this happens to make sure you can't fix it.
The side mission with Jesse happens.....and then this.
A whisper with Sephiroth's voice trying to keep Cloud sleep
A Whisper with Sephiroth's voice approaches Cloud in the morning. He wants him to sleep through Barret, Jesse, and Biggs going on the mission. This would have likely isolated Barret, resulting in his death. Something Jenova tries again towards the end of the game.
She really does not want Barret to stay alive, because he is the glue of Avalanche, and the main reason the events of the story begin the way they do. Cloud also likely never would have met Aerith in the church.
Jenova's whispers are trying to prevent Cloud, Tifa, Aerith, and Barret from getting together. This event would have succeeded in separating all of them.
That's why the whispers are at war with one another.
The Black ones are trying to isolate you. The white ones are correcting their meddling.
The game even STOPS you mid-combat to bring attention to the fact that the Black Whispers are being exposed.
Black Whisper being made vulnerable by something external
They stop attacking after a whisper manages to isolate and injure Jesse, at which point the battle is over and all whispers leave.
And of course....there's most obvious example of this kind of massive violation from Remake....The Infamous Chapter 18.
But that's gonna have to wait for another post.
I'm out of attachments again.

TL;DR : FF7R is messing with your head.

Aerith using the White Materia in Remake is literally going through the events of the story the exact same way the player did -- with "forbidden knowledge" about how things are "supposed to be".
In Rebirth, the White Materia is empty. She no longer has knowledge of what's "supposed to happen", and thus has to accept that whatever happens, happens. This is why the "The Journey is Unknown." Not because the party killed the whispers, therefore the writers can do whatever they want. But because Aerith hid her knowledge of the future (Holy) from herself. She used to be able to know what was going to happen. Now she can't. The real Meta thing is that FF7R only really starts to make sense when you willingly abandon what you thought you already knew about the story. Those who look with clouded eyes see nothing but shadows.
Now go back through Remake with the new perspective and tell me that everything doesn't make way more sense.
Also, please tell me im crazy so I can stop writing these.
Otherwise, stay tuned for pt3 -- The Black Materia.
....Oh. One final hilarious mindblowing. Remember this?
This is where Remake starts to fuck with your head. They're using the same memory effect for two different characters, for two different reasons. But the result is essentially the same -- the characters involved are having their perception altered.
Remake does NOT distinguish between static caused by Holy or static caused by Jenova. They are treated equally in Remake.
Rebirth DOES distinguish the visual effects of memory alteration.
But only for the player.
Cloud still can't tell the difference.
submitted by Kaslight to FFVIIRemake [link] [comments]


2024.06.01 11:07 lolqatz How do cell phones work?

My story takes place on an off-the grid Christian fundamentalist compound. There is no cell service, but church members are occasionally allowed to be taken off the compound and closer to a highway where there's enough connection to call their families.
The church leader grows increasingly paranoid, and performs a bonfire purge of all technology from the compound. All technology, except for a singular phone my protagonist finds belonging to a missing member and a charger he rescues from the fire at the last second.
Obviously, he can't call anyone, and there is no Wi-fi anymore. Over a year passes before he is able to escape the compound. My question is, when he does escape, would the phone still be able to make a call even if no bills have been paid on it for a year? If not to a specific person, then at least to 911? Sorry if this is a dumb question, I don't currently pay my own phone bill, so I'm not sure what happens when you financially abandon one.
submitted by lolqatz to Writeresearch [link] [comments]


2024.06.01 10:50 Yurii_S_Kh The Maiden Apostle

The Maiden Apostle
Archimandrite Raphael (Karelin)
https://preview.redd.it/xjqlop1j7x3d1.png?width=200&format=png&auto=webp&s=78843050264297aaf92b3908abeb526ee20c03ed
The most significant event in the history of Georgia was the country’s conversion to Christianity in the early fourth century by St. Nino, Equal-to-the-Apostles. The light of the Gospels brought by the virgin Nino to Georgia like a lamp lit from the fire of the Jerusalem church took flesh in the wondrous works of Christian literature and ecclesiastical art, in magnificent cathedrals resembling sculptures hewn from whole blocks of granite, in churches—stone blossoms that adorned the entire country as the garden of the Most Holy Theotokos, in chapels crowning the mountain peaks, so that the mountains and cliffs themselves are like footstools for the chapels. This light shines from the ancient icons and frescoes of extraordinary spiritual depth. This light sparkles in sacred chants. It illuminates the pages of Georgian Saints’ Lives and chronicles; but most importantly—the light brought by St. Nino changed and transformed the soul of the people.
* * *
Christianity made man a new creation. It gave him the dignity of the image and likeness of God, and revealed an imperishable spiritual treasure. Christianity turned man’s thoughts and heart to eternity. It gave his soul the possibility to be reborn and resurrected through mystical experience. Christianity revealed to man the true freedom of love, instead of the pagan freedom of passions and tyranny. Christian theology gave an answer to the age-old questions raised but not answered by philosophy. The Gospel teaching showed that each human personality—inimitable and unique—is of supreme value. Christianity became a powerful impulse for rethinking and developing the relationships between people and nations, founded upon respect for man as an image of God and a manifestation of eternity on earth. The light brought by St. Nino illumined Georgia’s historical path for many centuries. The Baptism of Georgia was the beginning of a new era in the spiritual life of its people.
The Gospel was first preached in Georgia by the apostles themselves. It was like the first rays of the sun that brighten the mountain peaks, as if tearing them from the captivity of darkness and night. Ancient ice and snow burst into flames of blinding light, but in the gorges and passes the fog still curls like the black smoke of a campfire. The world is sunk in pre-dawn night and sleep. The peaks illuminated by the light were the first Christian communities founded by the apostles. But the people remained in pagan captivity. Apostles Andrew the First-Called, Simon the Canaanite, and Matthew had cast the seeds of Gospel teaching into Georgian soil, but three centuries passed before this land would be covered with wondrously beautiful flowers. Just as the Aragva River changes its flow from south to west at the borders of Mshkheta, so did the Baptism of Georgia in the Aragva turn Georgia’s entire course of history from Iran to Byzantium.
The fourth century was a time of conversion to Christianity in the Caucasus Mountain region. Georgia’s brothers, Armenia and Caspian Albania, also converted, and this Christian house became an impenetrable fortress against their enemies.
St. Nino was, according to ancient tradition, a cousin of Great-Martyr George the Trophy-Bearer. There is a great similarity between the image of the knight who slays the dragon and the young virgin, who raised the cross in her hands like a spiritual sun over Georgia.
Georgia is the portion of the Most Holy Theotokos. The Virgin Mary chose a virgin to be the apostle of Georgia—St. Nino, who was almost a child at the time. With the cross as her sword she was victorious in battle with paganism, and illumined the nation with the light of the Gospel. She captivated people’s hearts with the fire of love, which Christ had brought from heaven to earth. She converted the people to Christ not with artful words, but through the power of grace. Nino’s chosenness was marked by the gift of miracles and healing. But the conversion of a nation through a young virgin was the greatest miracle. It is impossible to prove the existence of light—it has to be seen. St. Nino herself was a bright lamp; those around her felt this light with their souls, and beheld the eternal beauty of the Gospels. They received Nino’s preaching as a new life, hitherto unknown to them.
St. Nino lived from her childhood in a Jerusalem church under the care of her uncle, Patriarch Juvenal. This church was located on the slopes of Mount Sion, where the Holy Spirit had descended upon the apostles (the Church of the Resurrection of Christ the Savior had not yet been built). St. Nino grew up under the eaves of the church, similar to how the Virgin Mary lived for ten years in the Old Testament temple in fulfillment of her parent’s vow. The Virgin Mary had access to the Holy of Holies. The virgin Nino prayed in the place where the Holy Spirit descended in the form of fiery tongues and founded the New Testament Church in the upper room on Sion.
Jerusalem is a book made of stone, written about Christ. There the air preserves the breath of His lips, and the earth, His footprints. There, it is as if time has stopped, and it seems that Christ is near, like the time of His earthly life.
St. Nino lived at the church, like a nun in reclusion. The church is a concentration of spiritual light. Outside the church the light becomes dispersed and dim. In the silence of the church she heard the voice of angels, and in visions she conversed with Christ the Savior, as St. Paul conversed face-to-face with Jesus in the Arabian Desert. The Mother of God appeared to her as she did to the apostles after her Dormition. She saw with her spiritual eyes the beginning and end of the world. Prayer transfigured her. The young virgin seemed to be the embodiment of the spirit of ancient prophetesses, or angels who had taken on human appearance.
At the Savior’s will and the Mother of God’s blessing, she came from Palestine to the capital of Georgia, Mshkheta, which became a second Jerusalem. The day of her arrival, August 6, was the New Year and festival of the Zoroastrian divinity Ahura Mazda—the main festival of fire-worshippers. St. Nino entered into combat with Ahura Mazda and conquered him, as St. George conquered the dragon. The dragon was slain by the power of prayer, and the idol of Ahura Mazda fell and shattered into dust. This day became the spiritual new year in the life of the Georgian people.
Mshkheta greeted St. Nino with festival noise, solemn processions, and a sea of fires lit to honor Ahura Mazda. For Mazdaists, every first day of the month was dedicated to Ahura Mazda, and this first day of the year was celebrated with particular solemnity. On the left bank of the Kura River, opposite Mshkheta, King Parnaoz built a fortress and a pagan temple called Armazi. On the left side opposite Mshkheta, on the mountain peak stood idols of the Zoroastrian divinity, wrought of metal and decorated with precious stones. One of them held a bared sword in an outstretched arm and stood over Mshkheta like a conqueror, looking over the city from the heights of a citadel.
St. Nino fell to her knees and began to pray that the Lord would cast down the idols with His might, just as the idols of Memphis shook and fell when the Virgin Mary and her Infant passed through the city gates.
A miracle occurred. A storm arose. The horizon was darkened by clouds as if the sky was furrowing its brow. Dark clouds like black glaciers flows over Mshkheta. The sun’s light turned to dusk, as if time was turning back and night was on again. Lightning tore the clouds. The whole earth seemed to shake from the thunder. A whirlwind like a tornado flung Ahura Mazda into the gorge, like a knight throws his combatant from his horse. Torrential rain poured down mixed with hail, like molten metal and stones cast from battlements. The water of the Aragvi became covered with foam, as if it was boiling—waves heaved upwards, as if they wanted to reach the mountain peaks. It seemed that the river would crash over Mshkheta and drown it in its belly. People ran to their homes in horror. The city emptied, like a graveyard. But the storm passed as quickly as it came. Again the sun shone in the sky cleansed by wind and washed by rain. On the mountain peak there were no longer any idols to be seen, as if St. Nino had torn the military emblem from the walls of the Acropolis. In the thunder and wind, in the blinding flashes of lightning a new page opened in the Christian chronicles of Georgia, magnificent as Caucasus nature.
St. Nino began to live in the house of the king’s orchard keeper, the Jew Anastasios. Here she built a hut out of branches covered with clay on the edge of the king’s orchard. Her bed was a piece of wool felt thrown over the earth in place of a carpet, on which she prayed most of the night, falling asleep just before daybreak. On this site is built the Samtavro Monastery of St. Nino. In her desert cell is the cross made of grapevines, given to her by the Virgin Mary. This cross, a great sacred treasure of Georgia, is kept in the Sion Cathedral in Tbilisi.
In the Greek Chronicles, St. Nino is called Nonna; that is, nun and recluse. For the heart of a monk, the desert is the place where he meets Christ. St. Nino often withdrew to the outskirts of Mshkheta, especially to the mountain that is now crowned with the Dzhvari church, where the noise of the city and waves of the river would not disturb her silence. In the mountains the quietude is like an impenetrable, transparent crystal wall. There she prayed for hours to God, and when the first stars appeared in the sky, like candles lit by an invisible hand before an iconostasis, she would descend to the capital city, where the houses’ windows glowed like stars fallen from the sky.
St. Nino’s preaching was accompanied by manifestations of God’s power, especially the healing of the sick. Through the Jews who had settled in the Caucasus by at least the seventh century before Christ, the peoples of Georgia had been acquainted with Biblical teaching. Christian communities founded by the apostles in as early as the first century formed separate islands that eventually turned into an archipelago, spreading across the sea of paganism. By the end of the third century, Christianity was the second religion in size after Mazdaism. Georgia now stood before a choice: what should it be from now on—pagan, or Christian; what should they choose—the Gospels or the Avesta, the light of the Cross or the fires of Zoroaster?
Queen Nana, who had been healed of a mortal disease by the virgin Nino, became a Christian. King Mirian, son of a Persian shah, had been taught from childhood that Iran was the land of light, and east and west of it was the kingdom of darkness—Turan and Rome. The priests of Zoroaster convinced the king that Christianity is the herald of catastrophes prophesied by Zoroaster, that it is the religion of women and slaves, not worthy of an Aryan, that the true faith would perish through a woman, as one Indian sage had written five centuries before the birth of Christ, that Iran was created by great heroes who had conquered the devs (giants) from Turan, and because of the Christians the Jews perished and Rome was in decline.
The king was sunk in heavy doubts.
Where is the truth? Where should he lead his people? Will his descendants bless, or curse his name? The scales of history wavered in his hands, and no one knew which cup would drop lower. But the king’s doubt was resolved by a miracle—he was saved from fatal danger when he called upon the unknown God of St. Nino. King Mirian became the first Christian king of Georgia. According to the Greek chronologists, Georgia’s conversion happened in 318 A.D., and the Baptism of Georgia according to the Kartlis Tskhovreba (Life of Georgia) happened in 326, while the time of the hierarchical establishment in the Georgian Church came in 337.
The priests and bishops sent from Byzantium baptized the people of Georgia and Aragva. The place where King Mirian and his princes were baptized is called to this day the “courtiers’ font”. Downstream on the river, like in an enormous font, the people were baptized.
The fires of Zoroastrianism were extinguished in the waters of the Aragva; in the waves of the Aragva the blood of human sacrifices spilled to idols before the reign of Reva the Righteous (two centuries B.C.) was cleansed away, as was the filth of pagan theurgy and magic. The shards of shattered idols were thrown like corpses in a common grave in the Aragva. The Holy Spirit descended into the waters of the Aragva, as it did into the waters of the Jordan.
St. Nino traversed all of Kartli and Kakhetia with her preaching. She ascended to mountain settlements that were like eagles’ nests clinging to cliffs over the abysses. She preached in the courts of princes and in the huts of paupers. Day and night she spent in care for the newly baptized people, like a godmother for her children.
Nino performed the ascetic labors of her life in the eastern region of Georgia called Ereti, in the settlement of Bodbe. Like a gravestone on her grave stands the Church of St. George the Trophy Bearer. Here St. Nino rests in body, but in spirit she abides in every church, city, and village of Georgia. She abides in the heart of Georgia, and Georgia, in her heart.
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2024.06.01 09:17 Yurii_S_Kh “Rarely Have I Seen a Man So Noble as Fr. Dionisie”. Elder Dionisie the Athonite, Part 2

“Rarely Have I Seen a Man So Noble as Fr. Dionisie”. Elder Dionisie the Athonite, Part 2
Radu Hagiu
For the 20th anniversary of the repose of the holy and Venerable Dionisie of Romania and Mt. Athos (1909–2004), who will be canonized in 2025.
The following article was originally published in “Familia Ortodoxa” No. 5 (64), May 2014.
Cell of the Great Martyr George at Colciu Skete. Photo: Fr. Silviu Cluc
So you can direct your mind and it will be closer to God, forever…”
In 1965, when Fr. Gimnazie departed to the Lord, his beloved brother in flesh and spirit Fr. Dionisie was forced to take the wholeburden of the priesthood and spiritual fatherhood upon his shoulders; and in 1979, when Fr. Gedeon also reposed, he became the abbot of the cell, according to the rules of the Holy Mountain.
Father described the order of the ascetic life:
It’s exactly the same in the cells as it is in the monastery. You have a set time when you have to go read Vespers. There’s an appointed time after Vespers when you can refresh yourself with some food; a set time after dinner when you go read Compline. After that you go to your cell, and if there are a few hours left before you have to go to church, then you read the lives of the saints, that is, spiritual books that a monk needs to know—the lives of all the ascetics of piety. And you definitely have to complete your usual rule before the church bell starts to ring. You make 150 prostrations and go twelve times around your prayer rope with bows from the waist. It takes an hour or so. You should commune of the Holy Mysteries once every two weeks, because that’s how it was when I came to the Holy Mountain. After the service on Friday morning, you had to go tell your confessor about your thoughts, how you sinned, what you did. After you confess, go back to your cell and read the rule for Communion,
This is what he had to say about the rule of the Jesus Prayer:
In the Cell of St. Anna, the old-timer monks say that at the large skete, they would fulfill their rule and even the Vigil by praying the Jesus Prayer. Out loud. It was for everyone. They would go out to the middle of the church one by one and pray: “Lord Jesus Christ, Son of God, have mercy on us. Lord Jesus Christ…” And the other monks would listen attentively, not dozing. Then one of the fathers, adorned with grace, saw the Savior descend to the middle of the church and stand there, listening to their prayers.
Therefore, we have to say the Jesus Prayer. If a man, a monk, would say, “Lord Jesus Christ,” with every breath, then little by little he would learn noetic prayer and be adorned with it. Now it may be impossible for us to achieve noetic prayer, but to say the Jesus Prayer all day is the most blessed work. The enemy hears it and can’t draw near to you.
At the end of the twentieth century, with the arrival of Elder Joseph to Vatopedi Monastery and with the new flourishing of cenobitic life there, Colciu Skete also saw a multiplication of the number of monks, which rejuvenated and strengthened the old brotherhood.
A little later, God permitted a new trial for Fr. Dionisie: He lost his sight. Although he found it difficult to bear, as he was very physically active, Father later said:
“I prayed to the Mother of God to send me a gift: that I wouldn’t grumble from this blindness, and that she would have mercy on me. Now she’s made it clear to me that the state I’m in is good for me. And now I’m calm. It was and is useful for me to be like this.”
One of the few consolations left to Fr. Dionisie after he went blind was to sit on a bench near his cell and listen to the sounds of nature:
“When I listen for a bit, this is my consolation. Because if you can’t see anymore, then how can you rejoice? You have no joy at all. How many photos, how many icons I could see… but how to rejoice if you can’t see? But thank God! May God help us; may He fulfill my desire for holy salvation!”
Rarely have I seen a man so noble as Fr. Dionisie”
Archimandrite Ephraim, abbot of Vatopedi Monastery, with Elder Dionisie on the threshold of his cell
Fr. Dionisie gave rest to whomever knocked on the door of his cell. Romanians, Greeks, Russians, Bulgarians, laymen and monks coming from the most unexpected corners of the world would receive an answer to their existential questions and counsel and help to know the depths of their hearts and acquire peace. The Elder wasn’t like the sages of this age, and strictly speaking, he had no education; he spoke to everyone according to their needs. And as we knew him and understood him, three virtues remained in our hearts that he, whether by word or through his life, humbly placed before those who came to him thirsting to hear words of eternal life. And these three virtues are obedience, patience in tribulations, and humblemindedness,
recalls Archimandrite Ephraim, the abbot of Vatopedi Monastery.
When he learned that many people had photographed him without his knowledge, Fr. Dionisie lamented and said:
“What photos? What’s there to photograph? A poor old man who can barely walk? They want to make a saint out of me. But I’m like a dead man—a little while longer and I’ll be gone.”
Elder Joseph of Vatopedi
Elder Joseph of Vatopedi, a disciple of the great Elder Joseph the Hesychast, saw him as his co-laborer in prayer, and until his last days would visit Elder Dionisie for counsel and Confession, and other Vatopedi fathers would send various pilgrims to him who were looking for spiritual nourishment. Father would humble and reproach himself:
“Vatopedi keeps sending people to me, telling them I’m a spiritual man, but it’s not true. I can’t even see them—what am I supposed to tell them? I don’t have the gift of words! What should I, a poor blind man, tell them?”
Having attained the measure of perfected wisdom, Father taught his disciples:
We know that our way of life tends not to be so monastic anymore, receiving laymen, serving them, and this despite the fact that many come here only to tempt us. And we don’t really know their hearts; it’s all just how it seems to us. Let us try to have love, to show them love. Although we know that it’s hard and quite vexing, we have to do it so as not to harm ourselves from this side and that—because Orthodoxy doesn’t oblige us to see the mistakes of others, but to see ourselves, humble ourselves, and consider ourselves worse than all.
Perhaps the best description of Elder Dionisie’s earthly existence and angelic manner of living was given by the same Fr. Ephraim of Vatopedi:
He moved to the Cell of St. George at Colciu Skete in 1937, and until his departure to the Lord, he spent nearly seventy years in a humble room, all of fifty-four square feet, in patience and the thirst for silence. But he came to know Christ there and immutably understood that, as Geronda Joseph the Hesychast said, at the end of patience, when all human consolations are gone, the sweetness of Divine consolation descends into the heart.
His entire being breathed humility: his bright face, his warm smile, his meek and edifying word, his modesty, kindness, and simplicity, the way he hid his monastic labor and his deeds—in a word, his spiritual nobility. Rarely have I seen a man so noble as Fr. Dionisie.
May his blessing be upon us!
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2024.06.01 00:54 imz72 Phase 2 stem cell trial by Hope Bio (non-profit organization) in Long COVID fails to achieve statistical significance

Hope Biosciences Research Foundation Announces Topline Results of Cell Therapy Clinical Trial in Long COVID
May 31, 2024
SUGAR LAND, Texas, May 31, 2024--(BUSINESS WIRE)--Houston-area clinical research organization Hope Biosciences Research Foundation (HBRF) today shares topline results of a randomized, placebo-controlled Phase II study (NCT05126563) to evaluate Hope Biosciences’ adipose‑derived allogeneic mesenchymal stem cell therapy (HB-adMSCs) for patients with Post‑COVID‑19 syndrome.
The trial enrolled 79 participants, with 39 subjects in the treatment group and 40 in the placebo group; 34 participants completed the study from the treatment group, and 30 from the placebo group. The 26-week study mandated four infusions of 200 million stem cells, for a total of 800 million cells.
The primary endpoint was a visual analog scale (VAS) test for fatigue, in which 68% of subjects in the treatment group showed significant improvement (p=.0002) and 63% of subjects in the placebo group showed significant improvement (p=.001). Differences between the treatment and placebo groups were not statistically significant. Treatment was safe and tolerable in both groups. Detailed analysis is now underway.
"Our previous pilot study (Adipose‑derived, autologous mesenchymal stem cell therapy for patients with post‑COVID‑19 syndrome: an intermediate‑size expanded access program) with N=10 subjects demonstrated highly significant improvements in treating the symptoms of patients with long-COVID," explains Ridhima Vij, Ph.D., Clinical Research Scientist, HBRF. "Consistent with those findings, the current trial shows significant improvements in long-COVID symptoms. However, an unexpectedly high placebo effect was observed, masking the treatment effects, with both groups exhibiting significant improvements. This unprecedented placebo response suggests a need for further investigation."
Headquartered in Sugar Land, Texas, HBRF is exploring the effects of high volume, sustained application of adult stem cells on diseases and conditions that currently have no cure and affect substantial portions of the American population.
In addition to COVID and long-COVID protocols, HBRF has conducted and is pursuing work in central nervous system conditions such as Parkinson’s Disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), cerebral palsy, spinal cord injury, polyneuropathy, muscular dystrophy, drug-resistant epilepsy, and ataxia.
To date HBRF has obtained FDA authorization for more than 35 clinical protocols in these and other conditions, including in lupus, chronic musculoskeletal pain, severe osteoarthritis, psoriatic arthritis, stroke, palliative care, and pancreatic cancer.
The study announced in this release is made possible in part due to support from The John S. Dunn Foundation. Learn more at hopebio.org.
https://finance.yahoo.com/news/hope-biosciences-research-foundation-announces-204100491.html
Note: Per the study's page on ClinicalTrials.gov, the ages eligible for the study were 18 Years to 70 Years.
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2024.05.31 22:52 skkkrtskrrt HopeBio Phase 2 Trial outcome announced

https://www.businesswire.com/news/home/20240531123002/en/Hope-Biosciences-Research-Foundation-Announces-Topline-Results-of-Cell-Therapy-Clinical-Trial-in-Long-COVID
TL;DR: trial failed. no significant difference to placebo group.
Hope Biosciences Research Foundation (HBRF) today shares topline results of a randomized, placebo-controlled Phase II study (NCT05126563) to evaluate Hope Biosciences’ adipose‑derived allogeneic mesenchymal stem cell therapy (HB-adMSCs) for patients with Post‑COVID‑19 syndrome.
The trial enrolled 79 participants, with 39 subjects in the treatment group and 40 in the placebo group; 34 participants completed the study from the treatment group, and 30 from the placebo group. The 26-week study mandated four infusions of 200 million stem cells, for a total of 800 million cells. The primary endpoint was a visual analog scale (VAS) test for fatigue, in which 68% of subjects in the treatment group showed significant improvement (p=.0002) and 63% of subjects in the placebo group showed significant improvement (p=.001). Differences between the treatment and placebo groups were not statistically significant. Treatment was safe and tolerable in both groups. Detailed analysis is now underway.
"Our previous pilot study (Adipose‑derived, autologous mesenchymal stem cell therapy for patients with post‑COVID‑19 syndrome: an intermediate‑size expanded access program) with N=10 subjects demonstrated highly significant improvements in treating the symptoms of patients with long-COVID,” explains Ridhima Vij, Ph.D., Clinical Research Scientist, HBRF. “Consistent with those findings, the current trial shows significant improvements in long-COVID symptoms. However, an unexpectedly high placebo effect was observed, masking the treatment effects, with both groups exhibiting significant improvements. This unprecedented placebo response suggests a need for further investigation.”
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2024.05.31 17:55 CatScratch_Meow Books on cults/shadow governments/illuminati/conspiracies/religious scandals

I'm looking for books on corruption, hidden agendas, cults and conspiracies. I prefer non fiction but if you know of any good novels with these elements I would enjoy those as well. I'm reading Killers Of The Flower Moon right now. It's about the hidden plot to kill the Osage Native Americans to steal their money and land back in the 1920s. Another books I plan on reading is IBM And The Holocaust. Its about how the American company IBM aided in the genocide of Jews during WW2. A few fiction books with some of these themes I read are The Fifth Gospel, a book about biblical gospel that could prove the legitimacy of the shroud of turin and the lengths the church would go to surpress it. Another novel is When No One Is Watching. It's about the gentrification of an originally African American neighborhood and the disappearance of the neighbors day after day only to be discovered underground below the neighborhood in cells being experimented on. I know these books are all vastly different, I just enjoy the finding out about plots and hidden truths and a good twist. Don't be afraid to suggest books you think might be remotely related to any of these topics. I will appreciate anything 😊
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2024.05.31 16:02 lnnersanctum [M4M] Looking for Long-Term Horror Partner

Hey there! I'm looking for a fellow horror enthusiast to join me in putting OCs through the irreversible trauma of horrors beyond their comprehension. I've got a few vague prompts in mind to develop with you, but I am happy to brainstorm other ideas if none of them is to your taste.
A little bit about me and what I'm looking for: I'm 21+ and have been writing for about 12 years with the last couple of them being almost exclusively horror. I write in third person, sometimes in present and sometimes in past tense so I am happy to adapt to whichever you prefer. I am comfortable with writing in any length, any amount of characters. I love horror of any kind, but I am fascinated by the cosmic kind with religious and body horror sprinkled in. You can expect disgusting descriptions woven into holy imagery, yada yada yada. I am more than open to OC romance and smut as long as it's not the main focus.
I'm looking to write with someone also above 21 mainly due to the darker themes we'll be writing. I think it's really important to mesh well with the person you're writing with ooc, I'm not looking for an rp machine, rather someone who's willing to chat and be friendly ooc, talk about stuff we like, share memes (rp related or not), art etc.
Without lollygagging for too long, here are the prompts I've had in mind:
Along with these, here are some media and themes I like pulling inspiration from that we can brainstorm and come up with a unique plot over: The Magnus Archives/Protocol, Midnight Mass, The Hellbound Heart/Hellraiser, The Cthulhu Mythos, The Sandman, American Gods, Until Dawn, Sinister, Stranger Things, KULT Divinity Lost, Dead by Daylight, The Exorcist, IT, analog and digital horror... If anything I've said so far interests you drop me a chat and let's talk about it! Looking forward to hearing from you.
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2024.05.31 15:51 atmaninravi Who am I? How to Find Myself?

Have you ever thought about who you are? Are you John? That’s your name. Are you British? That’s your nationality. Are you a doctor? That’s your occupation. Do you hold a Ph.D degree? That’s your educational qualification. Have you ever thought about who you are? Are you John? That’s your name. Are you British? That’s your nationality. Are you a doctor? That’s your occupation. Do you hold a Ph.D degree? That’s your educational qualification. Are you a millionaire? That’s your financial status.
Who are you? Have you ever stopped to think?
Man has invented everything from submarines that go deep into the oceans to supersonic jets that fly in the sky. Man has discovered new lands, stars in space, a thriving underwater life, but man has forgotten to discover himself – who he truly is. It is only when man discovers himself, experiences a spiritual awakening that leads him to self-realization and God-realization, that he will be able to live a peaceful, blissful and happy life.

What We Are Not

So, we all think that we are ‘me’. But who is this ‘me’?
The best way to find out who or what we are, is to discover what we are not. As we keep eliminating what we are not, we will be rewarded with the realization of who we are. Are we this body? Everybody thinks, “I am this body.” But just like we have a car and a house, but are neither of these, we also have a body, but are not the body. If I say, I ‘have’ a body, then it certainly can’t be who I am!
If not the body, then we must be the mind. Our mind thinks, feels and remembers. Therefore, that must be who we are. But then, we feel our mind worrying, and we watch it wandering. Moreover, when we try to locate the mind, we cannot find it. Thus we realize that we may have a mind, but we are not the mind. We are distinctly different from it.
If we are not the body and the mind, then we could be the ego. But the ego is invisible and intangible. Then, how can we be the ego? We are the ones who have an ego, mind, and body but we are different from these. We know that we are none of these. There remains only one unanswered question after we know what we are not – ‘Who am I?’

We Live In Ignorance

Now let’s consider another analogy. We look at a gold ring, a necklace, and a bangle and think these to be different ornaments. The truth is that while these appear to be different pieces of jewellery, in reality, they are nothing but gold. Our mind doesn’t let us realize the truth that there is no bangle, no ring or necklace. It is only gold that appears in all these different forms. Remove the gold and there will be no ornaments.
We fail to realize who we truly are because our mind makes us live in ignorance. We are not able to go beyond the body, mind, and ego to realize who we are.

We are the Life Energy

We now understand that we are not the body or the mind or the ego. Then, who are we? Scientifically, when the smallest particles in the cells of the human body are examined under sophisticated instruments, they are proved to be nothing but energy.
Yes, the truth is that we are Energy. The Life Energy that causes our breath and without which, there would be certain death.
However, ‘mere knowledge’ of who we are is not enough. It is the ‘realization’ of the self that leads to everlasting happiness, spiritual enlightenment and liberation from pain and suffering. And to progress on the spiritual path to enlightenment, which is the only path to happiness, a seeker needs the guidance of a spiritual guru, besides the grace of God. A true spiritual master can help a seeker realize the self.
“What I see is not me. I am the one who sees. The Body may suffer, or the Mind may suffer, but that is not me!”

Post navigation

Are you a millionaire? That’s your financial status.
Who are you? Have you ever stopped to think?
Man has invented everything from submarines that go deep into the oceans to supersonic jets that fly in the sky. Man has discovered new lands, stars in space, a thriving underwater life, but man has forgotten to discover himself – who he truly is. It is only when man discovers himself, experiences a spiritual awakening that leads him to self-realization and God-realization, that he will be able to live a peaceful, blissful and happy life.

What We Are Not

So, we all think that we are ‘me’. But who is this ‘me’?
The best way to find out who or what we are, is to discover what we are not. As we keep eliminating what we are not, we will be rewarded with the realization of who we are. Are we this body? Everybody thinks, “I am this body.” But just like we have a car and a house, but are neither of these, we also have a body, but are not the body. If I say, I ‘have’ a body, then it certainly can’t be who I am!
If not the body, then we must be the mind. Our mind thinks, feels and remembers. Therefore, that must be who we are. But then, we feel our mind worrying, and we watch it wandering. Moreover, when we try to locate the mind, we cannot find it. Thus we realize that we may have a mind, but we are not the mind. We are distinctly different from it.
If we are not the body and the mind, then we could be the ego. But the ego is invisible and intangible. Then, how can we be the ego? We are the ones who have an ego, mind, and body but we are different from these. We know that we are none of these. There remains only one unanswered question after we know what we are not – ‘Who am I?’

We Live In Ignorance

Now let’s consider another analogy. We look at a gold ring, a necklace, and a bangle and think these to be different ornaments. The truth is that while these appear to be different pieces of jewellery, in reality, they are nothing but gold. Our mind doesn’t let us realize the truth that there is no bangle, no ring or necklace. It is only gold that appears in all these different forms. Remove the gold and there will be no ornaments.
We fail to realize who we truly are because our mind makes us live in ignorance. We are not able to go beyond the body, mind, and ego to realize who we are.

We are the Life Energy

We now understand that we are not the body or the mind or the ego. Then, who are we? Scientifically, when the smallest particles in the cells of the human body are examined under sophisticated instruments, they are proved to be nothing but energy.
Yes, the truth is that we are Energy. The Life Energy that causes our breath and without which, there would be certain death.
However, ‘mere knowledge’ of who we are is not enough. It is the ‘realization’ of the self that leads to everlasting happiness, spiritual enlightenment and liberation from pain and suffering. And to progress on the spiritual path to enlightenment, which is the only path to happiness, a seeker needs the guidance of a spiritual guru, besides the grace of God. A true spiritual master can help a seeker realize the self.
“What I see is not me. I am the one who sees. The Body may suffer, or the Mind may suffer, but that is not me!”

Post navigation

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2024.05.31 15:37 thelansis Oropharyngeal Squamous Cell Carcinoma (OPSCC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Oropharyngeal Squamous Cell Carcinoma (OPSCC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
https://preview.redd.it/xtffeq6rlr3d1.jpg?width=1275&format=pjpg&auto=webp&s=1bc52a8da30c89352e7784db4228d095eaa0397b
Oropharyngeal cancer is a condition where cancerous cells develop in the tissues of the oropharynx, which constitutes the middle part of the pharynx. This area encompasses the tonsils, the back of the tongue, and the posterior throat walls. The pharynx serves as a passage for both air and food. Oropharyngeal cancers are commonly associated with HPV, and a positive HPV-16 polymerase chain reaction test of a biopsy or fine-needle aspiration is suggestive of oropharyngeal origin. Most oropharyngeal cancers are squamous cell carcinomas, thin, flat cells that line the interior of the oropharynx. Oropharyngeal cancer is relatively rare and typically afflicts individuals aged 50 to 80. The primary risk factors are smoking and excessive alcohol consumption. However, there has been a rise in cases among younger people infected with human papillomavirus (HPV). The signs and symptoms of oropharyngeal cancer can vary depending on the specific location, type, stage of cancer, and the individual genetic makeup of the tumor. These symptoms may include A lump in the neck or throat, Difficulty chewing or swallowing, along with pain, Sore throat, Unexplained ear pain, A persistent sore or ulcer lasting more than two weeks, Difficulty in mouth opening or tongue movement, A persistent white patch on the tongue or the lining of the mouth, Coughing up blood. Risk factors for oropharyngeal cancer can be attributed to environmental, behavioral, or genetic factors and include Tobacco use (cigarettes, pipes, cigars, chewing tobacco), Alcohol consumption, Exposure to human papillomavirus (HPV), including HPV type 16, A prior history of head and neck cancer.
  • The global incidence of oropharyngeal squamous cell carcinoma (OPSCC) is estimated to range from approximately 95,000 to 112,000 new cases each year. Over the last few decades, the incidence of OPSCC has been on the rise due to an increase in cases of human papillomavirus-positive (HPV+) OPSCC.
Thelansis’s “Oropharyngeal Squamous Cell Carcinoma (OPSCC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Oropharyngeal Squamous Cell Carcinoma (OPSCC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Oropharyngeal Squamous Cell Carcinoma (OPSCC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Oropharyngeal Squamous Cell Carcinoma (OPSCC) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: Oropharyngeal Squamous Cell Carcinoma (OPSCC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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2024.05.31 15:19 thelansis Relapsed or Refractory Small Cell Lung Cancer (r/r SCLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Relapsed or Refractory Small Cell Lung Cancer (r SCLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
https://preview.redd.it/e0p47ih4ir3d1.jpg?width=1275&format=pjpg&auto=webp&s=007b21151ec1a40a79259e0307fcb9d758bc6f04
Lung cancer continues to be the primary cause of cancer-related mortality, with approximately 13% of lung cancer cases being diagnosed as small cell lung cancer (SCLC). Despite its sensitivity to chemotherapy and radiation therapy, nearly all SCLC patients experience disease relapse or progression. Topotecan, a water-soluble, semisynthetic derivative of camptothecin, stands as the sole FDA-approved second-line chemotherapy for relapsed SCLC, known for its specific inhibition of topoisomerase. In contrast, Amrubicin, also a topoisomerase inhibitor II, has demonstrated superior antitumor activity to topotecan, albeit it is currently approved solely in Japan. While multiagent chemotherapy has historically shown higher response rates in relapsed SCLC compared to single-agent chemotherapy, it often comes with increased toxicities. Given the frequent occurrence of relapses in SCLC patients, systemic therapy following first-line treatment failure remains a vital component of the treatment paradigm.
Thelansis’s “Relapsed or Refractory Small Cell Lung Cancer (r SCLC) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Relapsed or Refractory Small Cell Lung Cancer (r SCLC) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Relapsed or Refractory Small Cell Lung Cancer (r SCLC) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Relapsed or Refractory Small Cell Lung Cancer (r SCLC) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: Relapsed or Refractory Small Cell Lung Cancer (r SCLC) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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2024.05.31 15:12 thelansis Mitochondrial Myopathies (MM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Mitochondrial Myopathies (MM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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Mitochondrial Myopathies is a condition in which there is a defect in the mitochondria, which are energy manufacturers present in practically all body cells. Mitochondrial disorders that result in significant muscular issues are referred to as mitochondrial myopathies, whereas diseases that cause significant neurological and muscular problems are called mitochondrial encephalomyopathies. The three primary signs of mitochondrial myopathy are weakness, intolerance to exercise, and muscle exhaustion. Physical and neurological examinations and an assessment of medical and family history are typically part of the diagnosing process for mitochondrial myopathies. Diagnostic imaging, such as magnetic resonance imaging (MRI) or computed tomography (CT), is used for brain damage or anomalies in development. When a patient experiences seizures, the physician may prescribe an electroencephalogram (EEG), which records brain activity by applying electrodes to the scalp. The absence of vital mitochondrial enzymes in the muscle can be determined using different stains. Moreover, mitochondrial proteins from muscle can be isolated and their activity quantified. Physical therapy can help increase dexterity and muscle range of motion even though there is no known cure for any mitochondrial myopathies. Treatments consist of dietary supplements based on three naturally occurring compounds that our cells use to produce ATP: carnitine, creatine, and coenzyme Q10.
Thelansis’s “Mitochondrial Myopathies (MM) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Mitochondrial Myopathies (MM) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Mitochondrial Myopathies (MM) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Mitochondrial Myopathies (MM) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: Mitochondrial Myopathies (MM) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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2024.05.31 15:06 Yurii_S_Kh We Gave Up Everything to Find Salvation. Elder Dionisie the Athonite, Part 1

We Gave Up Everything to Find Salvation. Elder Dionisie the Athonite, Part 1
Radu Hagiu
For the 20th anniversary of the repose of the holy and Venerable Dionisie of Romania and Mt. Athos (1909–2004), who will be canonized in 2025.
The following article was originally published in “Familia Ortodoxa” No. 5 (64), May 2014.
Hieromonk Dionisie (Ignat)
An elder from Holy Mount Athos, from the mountain of prayer, the mountain of repentance, the mountain of tears, the mountain of ascetic labors, where the image of the Most Holy Theotokos reigns; from the mountain where, as someone once said, not a single man is born, but where they come to die—to sin, to the passions, to the lusts, ambitions, and vexations of this deceptive world, in order to ascend to where the glory of the world to come, the Kingdom of God, shines.
This is how Archimandrite Ephraim of Vatopedi describes the spiritual portrait of Elder Dionisie from the Colciu Skete.1
Elder Dionisie is a great Romanian spiritual father, revered by Athonite ascetics of all nationalities who inhabit the Garden of the Most Holy Theotokos. News of his holiness spread beyond Athos, and the old abba was visited in great number by hierarchs, priests, monks, and laymen, who asked him, as in the Paterikon, to give them “a word for the salvation of their souls.” And his main word, especially in his last years, was the following:
“We have to have spiritual friendship, for that’s love, and where there is love, there is God. And where there is no love, there is no God.”
Fr. Dionisie was an “old-fashioned” monk who tried all his life to adhere to the traditions he received from the elders and to pass them on to his disciples and spiritual children, for all seventy-seven years of his monastic labor.
We left everything we had and didn’t have in order to find holy salvation”
The Church of St. George in Suceava, where the holy relics of St. John the New are kept
The youngest child from the large Ignat family, which lived in the village of Vorniceni in Botoșani County, in Holy Baptism he received the Holy Great Martyr Demetrius as his patron saint. And at the age of two, God permitted that he lose his father.
Hieroschemamonk Dionisie (Ignat) and Monk Ioan (Sova)
Monk Ioan (Sova), who knew Fr. Dionisie well, said:
Their father was a very pious man; he and his whole large family often went on pilgrimage to the nearby monasteries together. Here’s a vivid example of his great faith. Once he went to venerate the holy relics of the Great Martyr John the New of Suceava, but he didn’t know the way and he asked everyone he met. But after a while, when he was still three to four hours away from Suceava, he smelled the fragrance of holy myrrh. He followed this fragrance, and found that it led him directly to the relics of St. John.
As the saying goes, “The apple doesn’t fall far from the tree.” This folk wisdom was fully confirmed by the Ignat family, where the children absorbed the spirit of reverence from an early age and tried to go to church and labor in prayer, come what may. The elder brother was the first to go to a monastery, at Magura Skete, and through him God poured the sweetness of monastic labor into the soul of his younger brother.
Magura Skete, 1945.
And so, in 1926, in the midst of the troubles caused by the calendar change, with the Church switching to the new style, young Dimitrie, who was only seventeen, together with his older brother Hierodeacon Gimnazie, left for the Holy Mountain. They had little idea what awaited them there, but they were burning with the fire of God’s call:
From the moment we arrived on the Holy Mountain, the Fathers always sought holy salvation; after all, that’s why we left our dear and beloved homeland, mother, father, and everything someone could have or not have—to find holy salvation.
In Constanța, they boarded a magnificent Romanian ship and arrived in Piraeus. They spent three days there then boarded a small, fragile boat, fiercely beaten by the waves. After long adventures, bypassing many islands, they reached Holy Mount Athos at the port of Daphne, where, to their joy, they found bread,
said Fr. Ioan (Sova).
Cell of St. George at Kapsala Skete.
“First, we went to the Cell of St. George in Kapsala. There were eighteen Romanians there. We arrived on the eve of the feast of the Nativity of the Most Holy Theotokos and immediately stayed for the All-Night Vigil,” recalls Fr. Dionisie about his arrival to Mt. Athos.
On the Holy Mountain, my soul felt contented, like nowhere else”
Elder Dionisie at the Hermitage of St. John the Baptist
“The Holy Mountain is called the Garden of the Mother of God, and rightly so, because the Mother of God came here for the first time and blessed this place, and then the locals became Christians. Therefore, everyone who comes here with the fear of God and reverence receives great help from her,” Elder Dionisie said with conviction.
He added, “Of course, everyone lives according to their own zeal on the Holy Mountain. But since the Holy Mountain is a special place, very special, my soul felt contented like nowhere else. I lived in a monastery in Romania for three years, and what can I say? Monasticism is wonderful there too. But here, Mt. Athos, is the place of hesychia.”
The Ignat brothers had to separate for some time to somehow earn their living in various monasteries and sketes, but already the next year, together with another Romanian monk, Fr. Gedeon, they managed to buy the Annunciation Cell under Pantocrator Monastery, where they could finally take up the work of prayer. Those were times of many hardships, but abundant grace, which he recalled with great love:
At first, we worked as farmhands, because times were different then, hard times… Life was different, with great difficulties, but the monks were much, much closer to God. Now we have very, very great facilities, but that true spiritual joy that we had when we were poor and destitute, and earned our daily bread with difficulty—we don’t have that joy now.
In the same year of 1927, he received the great and angelic tonsure into monasticism, and four years later he was ordained a hierodeacon to serve in the same cell. There, in the Annunciation Cell, they endured many temptations from the enemy. Demons made themselves seen and heard to frighten them so they would abandon their cell rule and harsh living. Sometimes demons appeared to them in the form of rabid black dogs that rushed at them, barking. But Fr. Dionisie’s brother, who was ordained a hieromonk in the same year, served the Divine Liturgy often, and the demons eventually disappeared.
In Colciu, there are two Romanian cells that are connected by great spiritual love”
In 1937, after nearly ten years of asceticism in the desert of the Holy Mountain, Fr. Dionisie and his co-strugglers moved to the Cell of St. George, which belonged to Colciu Skete, under Vatopedi Monastery.
“Here, in Colciu, there were eight cells similar to the Cell of St. George; some smaller, some larger; of them, six were Greek and two Romanian. And these two Romanian cells, which have been linked by love since time immemorial, have survived to this day,” says Elder Dionisie.
It was a much richer cell than the one in Karyes—it had olive, orange, lemon, nut, fig, plum, and cherry orchards and vineyards, and so on. And the garden had everything necessary for food: onions, garlic, tomatoes, eggplants, hot peppers, parsley, celery, cabbage, beets, potatoes, beans, and so on. The fathers called their garden “Monk’s Cow.” Located on the highest peak south of Vatopedi, along the eastern shore of Mt. Athos, the skete was very safe from visitors, as Father described it:
“This is the desert of Colciu. It’s still good now, but no one used to come before, because, as you can see the way Mount Athos is formed, Colciu is off to the side, far from the main roads. You have to come specifically to Colciu, otherwise, you won't get here!”
Colciu Skete.
Due to the vicissitudes of history, no more monks were coming, and the skete became completely desolate, falling into disrepair. The little brotherhood made every effort to restore the buildings, having building materials delivered to the harbor from afar, then carrying them up to their cells on mules.
But their physical labors were doubled by their spiritual asceticism. The brothers diligently celebrated the Church services and cell rule, following the Athonite regulations:
“The statutes of the Church, the monasteries and cells, are exactly the same today as I found them when I came to the Holy Mountain so many years ago. Only, people were much simpler then,” Fr. Dionisie humbly confessed in his old age.
Attracted by the good order there, which brought spiritual growth, more and more monks began to gather, increasing the ranks of the brotherhood.
However, amidst all the labors and troubles, God also sent consolation to His fervent devotees. Once, one of the monks’ cells there, which housed an icon of the Kazan Mother of God, caught fire.
Fr. Ioan (Sova) recalls:
The entire floor burned, along with the furniture and the books, but the window frame, the door, the table where an icon stood, and the floor under the table remained untouched! When Fr. Dionisie opened the door, the room was full of smoke, and it hit him hard in the face. Once he was able to look inside, he saw the icon untouched by the fire and a lampada burning before it on the table, and it seemed the face of the Theotokos was smiling.
But the enemy, of course, didn’t stop plaguing the ascetics. Fr. Dionisie recalls a few instances:
There was one brother, Gabriel, living next to our cell. One day, going to church, he suddenly started shouting, pointing towards the sea. He was too far away for us to hear him, so we went to him and asked him what all the fuss was about. He said that when the bells started ringing for the start of the service, he saw demons coming up from the sea like a swarm of bees. They were coming to tempt the monks who were gathering for prayer.
Another time, during the All-Night Vigil, between Vespers and the start of the Six Psalms, when everyone in the church was standing in stasidia listening to the word being read, one of the monks, Fr. Arsenie, saw a dark figure dressed in black (he couldn’t see his face) come into the church, holding something like a censer in his hand. When the vision approached the monk, he froze. Fr. Arsenie was terrified, and when the vision drew near to him, he screamed with all his might. And then everyone woke up. You see? A monk is a warrior fighting against the devil.
To be continued…
1 From the three-volume series Elder Dionisie, published by Prodromou Skete in Romanian in 2009.
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2024.05.31 15:03 thelansis Septic Shock – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Septic Shock – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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Septic shock has a significant fatality rate. Sepsis syndromes are the most serious sepsis consequence. An inciting substance triggers pro- and anti-inflammatory immune system activation, leading to septic shock. The immune system's pro- and anti-inflammatory branches activate in response to an inciting agent. Monocytes, macrophages, and neutrophils are also activated. These cells interact with the endothelium via pathogen recognition receptors to produce cytokines, proteases, kinins, reactive oxygen species, and nitric oxide. A continuum of pathophysiologic states, beginning with Systemic Inflammatory Response Syndrome (SIRS) and culminating in multiorgan dysfunction syndrome (MODS) before death, known as sepsis. It is recommended that septic shock be addressed with an interprofessional team. Differential diagnosis: Myocardial dysfunction, Acute/chronic renal injury, Mesenteric ischemia, ARDS, and Multiple organ failure. Sepsis patients are at significant risk for several consequences that lead to death.
  • Every year, sepsis, a potentially lethal immune reaction to infection, affects 1.7 million individuals in the United States.
Thelansis’s “Septic Shock Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Septic Shock treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Septic Shock across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Septic Shock Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: Septic Shock – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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2024.05.31 14:58 thelansis Chronic Fatigue Syndrome (CFS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033

Chronic Fatigue Syndrome (CFS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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Chronic fatigue syndrome (CFS), also referred to as myalgic encephalomyelitis, presents as a multifaceted multisystem disorder characterized by profound fatigue, cognitive impairment, sleep disturbances, autonomic dysfunction, and post-exertional malaise. These symptoms significantly impede patients' capacity to engage in daily activities. The etiology of CFS remains contentious and intricate and needs to be fully elucidated, with debates surrounding single versus multiple causative factors. The pathophysiological mechanisms underlying CFS still need to be fully comprehended. It is proposed that alterations in the nervous system occur as a secondary response to the body's inadvertent reactions to commonly encountered antigens. These alterations encompass changes in cell-mediated immunity, activation of oxidative pathways, and modifications in neuroendocrine and autoimmune responses targeting neurons. In the management of CFS, nonsteroidal anti-inflammatory drugs (NSAIDs), including COX-2 inhibitors, are utilized for their efficacy in alleviating pain and associated inflammation. Opioid medications, while effective, are reserved for severe cases and administered for the shortest possible duration due to their addictive potential.
Thelansis’s “Chronic Fatigue Syndrome (CFS) Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033" covers disease overview, epidemiology, drug utilization, prescription share analysis, competitive landscape, clinical practice, regulatory landscape, patient share, market uptake, market forecast, and key market insights under the potential Chronic Fatigue Syndrome (CFS) treatment modalities options for eight major markets (USA, Germany, France, Italy, Spain, UK, Japan, and China).
KOLs insights of Chronic Fatigue Syndrome (CFS) across 8 MM market from the centre of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Chronic Fatigue Syndrome (CFS) Market Forecast Patient Based Forecast Model (MS. Excel Based Automated Dashboard), which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Thelansis Competitive Intelligence (CI) practice has been established based on a deep understanding of the pharma/biotech business environment to provide an optimized support system to all levels of the decision-making process. It enables business leaders in forward-thinking and proactive decision-making. Thelansis supports scientific and commercial teams in seamless CI support by creating an AI/ ML-based technology-driven platform that manages the data flow from primary and secondary sources.
Read more: Chronic Fatigue Syndrome (CFS) – Market Outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2023 To 2033
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2024.05.31 13:28 Yurii_S_Kh Proposed for canonization: Gerondissa Makaria, who uncovered the relics of St. Ephraim of Nea Makri

Proposed for canonization: Gerondissa Makaria, who uncovered the relics of St. Ephraim of Nea Makri
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Gerondissa Makaria (Desipri), former abbess of the Holy Annunciation Monastery in Nea Makri, who was vouchsafed to uncover the relics of St. Ephraim of Nea Makri in 1950, has been formally proposed for canonization.
The joyous news was announced by Metropolitan Kirill of Kifissia while serving at the monastery yesterday. The hierarch has already turned over the relevant file and documents to the Holy Synod of the Church of Greece, which will then pass it on to the Patriarchate of Constantinople, reports the Orthodoxia News Agency.
Gerondissa Theodosia, who governed the monastery after Gerondissa Makaria was also a holy woman. When she reposed on the feast of the Nativity of the Theotokos in 2022 at the age of 103, the whole monastery was filled with a bright light.
***
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Gerondissa Makaria was born on March 12, 1911, in Tinos. At the age of 19, she decided she wanted to become a nun. During the occupation, she lovingly cared for the children of prisoners. In 1945, she visited the then-men’s monastery on Mount Amomon, where she lived for several years under difficult conditions. Her health was greatly tested during this time. She slept in the ruins of the monastery, without windows and coverings, enduring every hardship.
Moved by Divine inspiration, she set up a small cell there and began clearing the ruins of the old church to reconstruct it. She often pondered that monks had lived there over the centuries and prayed to meet or be revealed one of them. A voice, initially faint but growing stronger in her soul over time, told her: “Dig and you will find what you desire,” until a spot in the monastery courtyard was revealed to her.
On January 3, 1950, she instructed a worker to dig at the specific spot her soul had indicated. Despite the worker’s initial reluctance and preference to dig elsewhere, he was persuaded by her pleas and prayers to start digging. The spot contained a half-ruined fireplace, wall, and remnants indicating it was once a monk’s cell. The first discovery was a head, and the area emitted a fragrance.
“I knelt reverently and kissed the relic of the saint, deeply feeling the extent of his martyrdom. My soul was filled with joy, and I had acquired a great treasure. Carefully removing the soil, I saw the harmony of his relic, which, despite centuries in the ground, had not decayed,” wrote Mother Makaria, describing the profound events.
With care, Abbess Makaria removed the entire relic and placed it in a niche above the grave. It was evident that he was a cleric, as his cassock remained intact.
That night, while reading Vespers, Mother Makaria heard footsteps coming from the grave, echoing to the church door. There she first saw him. He was tall with small round eyes, long black beard reaching his neck, dressed in monastic garb. In one hand, he held a flame and blessed with the other. He asked to be removed from the niche where he was placed. The next day, the Abbess cleaned the bones and placed them in a niche in the church sanctuary.
That same night, the saint appeared in her dream, thanked her, and revealed his name: Ephraim. The relic of St. Ephraim has been kept there since, with hundreds of faithful visiting daily to seek his blessing and assistance. By God’s grace, the saint has performed thousands of miracles. In the monastery courtyard, protected by a structure built around it, stands the mulberry tree where St. Ephraim took his last breath.
Without financial resources, she maintained an orphanage until 1980 with about 70 school-aged children, providing them with shelter, food, clothing, and elementary education. Those who excelled academically were supported through higher education, and today they testify that she “nourished them from nothing.”
Though lacking a university education, she published Patristic texts, Ascetic Words of Saint Basil the Great, and composed a Supplicatory Canon and Akathist Hymn to her beloved St. Ephraim, recording and gradually publishing his miracles in 16 volumes to support and strengthen the faithful.
The Lord of Glory allowed Mother Makaria, in her old age, to bear a great cross. She bore it with patience and silence, facing her trial as a blessing from God. Her passing was peaceful and saintly, as she had predicted more than 20 years prior.
Her holy soul, surely guided by her great martyr St. Ephraim, ascended to the Heavens after receiving the Holy Mysteries. It was Friday, the feast of St. George the Trophy-Bearer, April 23, 1999.
Today, her much-suffered venerable body lies in the remote grave she had dug years earlier in the courtyard of the monastery, where by God’s grace, she was the foundress and abbess for half a century, “to hear the hymns and witness the glorious and wondrous deeds the saint performs for those who come to his holy monastery with faith.”
Orthodoxia News Agency
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2024.05.31 11:06 DoctorEnn The Eraser (some lore)

The GCPD don’t make jokes about him anymore.
They used to. Back when they thought they knew the rules. Familiarity breeds contempt, after all. They’d let the freak handle the other freaks, even if he didn’t go all the way like he should have, but the Blue Wall was too big even for him. He’d know his place or get crushed.
So yeah, there were jokes. And some of the braver cops even made those jokes when in earshot.
(Never face-to-face, though. Funny that. Not a single cop was brave enough to make those jokes with him standing right in front of them.)
But not anymore.
Thank Lenny Flasco. CSI tech, out of the 65th. A real entrepreneur, Lenny. Had a sideline in selling evidence from high-profile crime scenes. Quickly figured out how to make bigger profits. Made it known that, for a generous fee, he’d make sure you never got caught. It’s easy for fingerprints to get smudged, after all, or evidence to be contaminated. Had a good thing going for a while there.
Thing is, Lenny fancied himself an artist. Was aiming for the big time. And, well, you need a gimmick in this town to get noticed. And he’s kind of an asshole, is Lenny, and one day he happened to get the term ‘pencil-dick’ thrown his way, and a synapse fired.
And the Eraser was born.
To be honest, even in Gotham the helmet got him some odd looks. But he was too damn good at what he did for people to make a big deal. Guy practically was a human eraser anyway. Robberies, rapes, murders, whatever you did, he could make it disappear. Make it like you were never there. It was almost like rewriting reality. And no one even noticed.
Well, almost no one. A lack of evidence can be its own type of evidence, after all.
But he couldn’t do anything. No evidence chain to follow. And besides, the Eraser knew the nature of the Blue Wall. The wealth was spread generously. Too many cops benefitted for the game to stop, and even among the ones that didn’t there was the joy of rubbing in exactly who was in charge in this town. And if a few victims went without justice and a few lives got ruined, well, shit, que sera, you know? Their fault for not being able to buy justice in Gotham. Just the way the game is played. Suck it up.
So, life was sweet for the Eraser. The mobs were eager to pay, as were the wealthier perps. Plenty of uniforms and detectives and ADAs willing to spread the word for a cut. Things got so good that for a while there he practically ran CSI. You wanted a conviction, you had to run it by the Eraser first, make sure he hadn’t set up an arrangement.
Yep, for a while there, things were pretty sweet.
Then Trent Davenport happened.
Trust fund asshole, heir to the Davenport millions. Streamer and social media influencer, which just meant idiots gave him money he didn’t need to be a too-online rich asshole with some barely coherent far-right views. But one night, after some media event, Trent got coked up with a thousand-dollar-an-hour call-girl and took her on a joyride around the Adams Expressway in his Mercedes. Got into a fender bender with a family sedan and went off on the occupants. Lifelong Gothamites, but with enough visible Puerto Rican and Guatemalan ancestry to set Trent off. The resulting racist tantrum, recorded by security cameras, both dashboard cams, and at least 100 onlookers, would have ordinarily have just prompted a tearfully insincere apology on social media the next day… except Trent pulled out a ridiculously large gold-plated handgun and filled the sedan – and family – with bullets. Only the youngest, Celia, survived.
Frankly, Trent’s brief career as a criminal didn’t cover him with glory. He barely made it to the city limits before he caught up, and it wasn’t even an especially difficult collar; Trent basically pissed himself at the first glimpse of a cape. And there was so much evidence that he wasn’t even really needed. Hundreds of witnesses, video footage, a custom handgun, a custom car with custom plates… even the GCPD couldn’t screw this one up.
But Daddy Davenport didn’t like the idea of his son and heir, useless waste of DNA he might be, bringing that kind of shame on the family name. Certainly not just over a car full of brown people. So, when a cop sidled up to him and suggested a solution, he listened.
And the Eraser went to work.
In a twisted way, it was genius. A work of art. All that evidence somehow evaporated. Even the call-girl who’d been next to Trent all the time was somehow seen at the other side of the city when it happened. It was like someone had managed to hack reality. When it came to trial, the thing had been cleaned up so efficiently that the judge – one of the most honest in Gotham, no less – had no option to throw the whole thing out with prejudice.
It didn’t matter how much the little people in the courtroom exploded. Trent Davenport swaggered out, made a smarmy comment to the press hoping the “real culprit” would be found, implied he was gonna sue the little girl and her surviving family for damages, and hopped into a substitute for masculinity to prepare for his celebration party. That night, at one of Gotham’s most elite club. Only the most beautiful and the most elite would be there. Entry cost, your soul, but a price too many were willing to pay if it meant a night they wouldn’t forget.
And so, Gotham sank a little further into the muck. Felt a little rottener and more hopeless. When even Plastic Man couldn’t crack any jokes on TV that night, you know something had broke.
The GCPD were worried. Incredibly – and somewhat ironically, given how things turned out – they were as shocked by what happened as everyone else. They actually hadn’t approved this fix. They might be many things, most of them rotten, but they weren’t stupid. They knew how Trent Davenport strutting away from getting caught murdering three people practically red-handed would look. They knew they were only hanging on to whatever public support they had by a thread. They knew fucking over an orphaned six-year-old in public was the last thing they needed. They knew the city only needed a spark to explode. And some of them even had consciences. Trent Davenport was too rich to get the whole book thrown at him, but he needed to hit with a few pages at least.
No, this one was all the Eraser. He’d gone off the reservation. Because Lenny had been getting greedy, Lenny had been getting cocky, and worse of all, Lenny had been getting bored. The usual heists, drug deals gone wrong and accidentally dead hookers were beginning to bore him. He wanted a real challenge. And part of him wanted to show everyone who was really in charge of this town. Who really decided who was guilty and innocent, what was true and lie, reality and fantasy.
So, the GCPD got out the riot suits and tanks, ready to crack a few heads… but the streets were weirdly quiet. There’d been the usual pleas for calm, but it didn’t feel like people were listening. No, it felt like people were mostly… bunkering down. That there was some weird collective, animalistic instinct spreading through the people of Gotham, telling them there was a storm coming and that no one wanted to be on the streets when it hit.
Oh, how right they were.
Because there was another victim of crime in Gotham City. A victim who looked at a little girl with a void in her life she’d have to live with forever and saw himself. A victim who had felt that powerlessness and despair and hopelessness only too keenly.
A victim who had made a Vow.
A victim who went to work.
Trent Davenport really enjoyed his celebration party. Especially enjoyed the feeling that he really was untouchable. Looked forward to proving it with a few hot bitches who caught his eye. They wouldn’t say no. Even if they wanted to. Because he could do whatever he wanted to whoever he wanted.
Yeah, Trent really enjoyed himself that night.
For about forty-seven minutes. Until the gate crasher arrived, and the storm began.
The beautiful elite of Gotham certainly got an experience they wouldn’t forget that night. Not the one promised, however. They spent it cowering in the blacked-out ruins of an elite rooftop nightclub, the power dead, the exits blocked, the only source of light a ragged hole in the ceiling. The only sound the screams of an influencer, snatched from the floor under cover of darkness, as he whined and shrieked that he didn’t know who fixed his trial, that it was Daddy who cleaned up his mess like always, that he was sorry and would never do it again, oh God, he’s sorry, please stop, he’s so so sorry
They never did figure out how the sound system still functioned despite all the damage to the electronics.
(Incidentally, you don’t see Trent online much these days. He shies away from the spotlight. Not just vanity, though the surgeries have mostly restored his former looks. Or the legal troubles, though he no longer has the income streams he once had. He just doesn’t really have the time for content creation these days. Or politics. Or partying, or fast cars, or girls, or skiing, or anything, really, outside of relearning to walk. Turns out, Trent couldn’t do anything he wanted. Flying, for example, remained beyond him. As he made abundantly clear.)
Then it was Roland Davenport’s turn. He faired comparatively better to his son. But as one of the wealthy and powerful of Gotham City, he wasn’t used to inconvenience. Or pain. Which meant it only took a broken nose, a few good punches, and about thirty seconds dangled off a penthouse balcony for him to begin screaming about a detective, possibly called Kline or Keane or something else beginning with ‘K’, who offered to put him in touch with someone who could make his son’s latest screw-up disappear. But he never met this ‘Eraser’ directly, it was all handled by intermediaries…
And that’s the problem with Gotham: there are so many intermediaries.
So he decided to go through all of them.
The GCPD was so preoccupied with the possibility of riots that it took Dispatch a while to realise certain officers were beginning to go AWOL. Just completely dark, no communication at all. But it somehow took them longer than it should have to realise the connection: from the first beat cops on the scene to the precinct captain, all the missing officers had at some point worked the Davenport case.
And then those same officers began showing up in emergency rooms. Or walking into precinct houses or churches desperately begging to confess their sins. Or, in one notable case, were found in their patrol car as it was dangling off the Azzarello Bridge by a cable. They found Detective Andrew Kendall at the altar of St Jerome’s naked from the waist up, on his knees, arms wrapped around the parish priest and sobbing, desperately begging for someone to absolve his sins because he’d had a taste of Hell and didn’t want any more…
And then more began to join them. It’s still one of the worst nights in GCPD history for 10-13 callouts. There weren’t enough cops to cover all the cops who were suddenly screaming into whatever device was closest to them that they were under attack, they needed immediate assistance, oh God, they think it’s the—
Cops from all over the city. Cops guilty of any number of sins. But who all, some bright spark eventually realised, had one particular sin in common.
And then the entire 65th Precinct went offline.
Word is, every single SWAT officer present refused to even enter the building. Five tactical units, twenty men a piece, and every one of them said no way. Apparently, not even one of them wanted to risk being caught alone in the dark. There’s a photo of Commissioner Loeb literally stamping his foot and screaming at a guy like a toddler which somehow managed to slip through the media blackout and blew up on social media. Apparently his now-customary death orders didn’t carry the same weight they once did.
They eventually did storm the building… when the lights went back on. The place was a war zone. Cops sprawled everywhere. No fatalities, but plenty wishing they were. The lucky ones were just unconscious. A few of them – the clean ones – were unharmed, but this was the 65th, so there weren’t many of them. Non-badged criminals were all sitting in the cells, quiet as kittens, not making trouble. Not wanting to attract any attention. The precinct’s forensics team were found huddled together in the remains of their office, cowering and whimpering, but for the most part physically unharmed. They weren’t much help, though. The most lucid one just kept sobbing “I’m sorry” over and over.
The most useful comment came from a witness who’d been processed for possession when the storm hit. He just looked the interviewing officer right in the eye, and said “He’s out for blood tonight, bro.”
Lenny Flasco was nowhere to be found.
Oh yes, the Eraser had seen it coming. And he’d made plans, because he was smart, and cunning, and a slippery little asshole when all was said and done. Oh yes, Lenny was well away from the 65th by the time the storm showed up, and he was planning on being even further by the time the evening was through. Somewhere nice and sunny and sandy. He had plenty of money to enjoy it now, after all.
But you know what they say about plans and the enemy.
Because, like all plans, the Eraser’s hinged on other people helping him out. And by that point, those other people had also realised the nature of the storm passing through Gotham. And who was the focus of it.
Connections suddenly started drying up. Phones weren’t being answered. When they were, people were pretending not to know who was calling. Finally, someone had to spell it out: the Eraser was marked, radioactive, and no one with two brain cells to rub together wanted to be between him and him. Even Two-Face didn’t need to flip the coin to make that decision. The Eraser was persona non grata. He’d been cut loose. Erased.
You might feel a small stab of pity for the Eraser at this point: he’d made millions on his fixes, but none of it would even buy him a cup of coffee in this town. Word is, last anyone saw of him when he could still stand under his power, he was desperately trying to force a bag full of thousand-dollar bills into the hands of a sketchy car dealer who was equally desperately trying to pretend he wasn’t even there over some shitbox. He was still wearing that helmet.
No one else knows if the Eraser managed to get the car or not. But they do know he didn’t get somewhere sunny and sandy. Unlike Trent, he didn’t even get to the city limits before the storm finally hit him.
Next time anyone saw the Eraser, he was lying in a mangled and whimpering heap on the floor of Commissioner Loeb’s office, tangled in black fabric. He’d been thrown through the window. Forty-nine floors up. With him was a recorded confession, detailing every crime he’d covered up. No one’s been willing to listen to it more than once. And even with that, a week later, when he woke up in the hospital, the only thing he’d say was “I confess.” His physical injuries healed surprisingly quickly, but his brand-new stammer doesn’t seem to be going anywhere fast. Or his night terrors. To this day, no one’s managed to figure out exactly what he did to the Eraser.
They know what he did with that stupid helmet, though; it’s still impaled on the tip of Lady Justice’s sword. No one’s been able to figure out how to get it down.
Or if they should.
A lot of cops left after that mess. Not enough to really change things, but enough to make people notice. Some of them – not enough, but some – left facing criminal charges. More just quietly took early retirement. Trauma, they said. They couldn’t handle the pressure anymore. What specific pressure they couldn’t handle went unsaid, but everyone knew. For months after, there were stories of cops having panic attacks just after being assigned the night shift. Some were physically invalided out. No one likes to think about them. (There’s a significant overlap between these ones and ones facing charges.)
And the ones who stayed, clean or dirty, even they couldn’t help but notice a gradual change in the GCPD. The rot didn’t disappear – it was too deeply embedded, for that – but it wasn’t like before, when the times were good, the money was flowing like wine and you could laugh at the jokes about the freak. Now, someone offers you a kickback, someone offers to make it worth your while to look the other way or fix a problem, someone even makes a joke about bats, every time you feel a sudden cold chill, and you can’t help but think: that he might be watching. That he might somehow know. That the only reason you’re even still here might just be because he allows it. That he doesn’t kill only because there are worse things than death, and he can summon them. And that some night, when you’re alone on the mean streets, no backup in sight, the shadows might suddenly move, and it might be your turn for your sins to catch up to you, to get yours like the Eraser got his…
…No, the GCPD doesn’t make jokes about him anymore.
submitted by DoctorEnn to LegendOTCapedCrusader [link] [comments]


2024.05.31 00:47 waray-upay Iglesia ni Cristo, Divorce, and the concept of the Total Apostasy

In this article, I aim to highlight the inconsistency within the Iglesia ni Cristo, which believes in total apostasy while staunchly rejecting divorce. Total apostasy, likened to Christ divorcing His wife, the Church, contradicts their firm stance against divorce.
Note: This is not an argument for or against divorce.
The concept of apostasy holds deep implications, touching the core of Christ's relationship with His Church. At the heart of this theological debate lies a profound biblical truth: the inseparable bond between Christ and His Bride, the Church. Yet, within discussions of total apostasy, a challenging assertion arises—one that questions the foundation of this sacred union.
To explore this assertion, one must first understand the theological significance of Christ's relationship with His Church. In Iglesia ni Cristo doctrine, the Church isn't just an institution but the mystical Body of Christ, united with its Head.
Central to this bond, according to INC, is the sanctity of marriage, symbolizing the union between Christ and His Church. The Apostle Paul elaborates on this mystery in Ephesians, likening the husband-wife relationship to that of Christ and the Church (Ephesians 5:22-33). In this analogy, Christ is the loving bridegroom, and the Church is His cherished bride, adorned with His grace.
Against this backdrop, total apostasy poses a theological dilemma. Suggesting the Church has apostatized implies a rupture in the bond between Christ and His Bride. It insinuates that Christ, the faithful bridegroom, has abandoned His beloved Church, divorcing her for a new union with the INC.
This proposition not only undermines Christ's unwavering love but also contradicts His teachings on marriage. Throughout the Gospels, Christ upholds marriage's sanctity, denouncing divorce as against God's intent (Matthew 19:3-9). To propose Christ would forsake His Bride, the Church, and enter a new union with INC distorts His teachings and diminishes His divine character.
submitted by waray-upay to exIglesiaNiCristo [link] [comments]


2024.05.31 00:47 pjeskoRiba Clarification in regard to "No Sexual Relations"

***TL;DR: Provided below**\*
Hey guys! Throwaway account here, but I have been trying to define where the lines are in regard to the Law of Chastity. To start, I do consider myself an active, faithfully trying member to come more in line with God's will (hence the request for others' opinions). To let you guys know where I am at, I have made the following conclusions. (Keep in mind that I'm a single RM as that seems like important context. Also that everything listed below assumes all parties consented)
First, the list of my potentially controversial OKs (Not a sin)
-Passionate kissing is OK
-Lying on top of another person is OK
-Masturbation is OK
-Seeing/being with somebody nude is OK
-Fondling the breasts or butt of another person (with or without clothing) is OK
I know most of these go directly against some of the older teachings of the Church including the old For Strength of Youth pamphlet. But, I personally feel that most of those these things were guidelines to keep your cart away from the cliff. Passionately kissing while lying on top of another person, seems to be a way to drive with one wheel off the cliff to borrow an analogy from the Miracle of Forgiveness.
Now what seem to me to unequivocally be sexual relations
-Penetrative sex (whether vaginal or anal)
-Oral sex
Gray area to me, for which I'm mostly seeking clarification
-Manual sex (To me this seems to definitely be a sin and I do feel guilt in my soul the couple times I have done this, but do you guys think this counts as a sexual relation?)
-"Touching the private sacred parts of another person" (I feel this is probably a sin, but to me doesn't seem to count as a sexual relation)
-Fantasizing or envisioning another person sexually (imaging them nude, having sex with them etc.) Obviously a sin, gross as well, but also not a sexual relation.
-Viewing/reading porn (essentially the same as the above in conclusion)
-Masturbating to porn/fantasy of another person/memory of a sexual experience (Seems like more of a sin then just putting your mind in that space, but also doesn't seem like a sexual relation)
I know a lot of the way I phrased these things sounds like I have come to unwavering conclusions, but I'm actually super open to what you guys have to say. Personally, I fear that some of these conclusions are, at root, a way to protect myself from the potential reality that I may have pushed the Spirit out of my life in ways that would take years to repair. I want to know what you guys (strangers) think as I would like opinions from all stages of life/activity in the Church..
TL;DR: I'd like your opinion on what counts as violating our covenant to not have any sexual relations outside of marriage.
submitted by pjeskoRiba to ldssexuality [link] [comments]


2024.05.31 00:22 realdavidguitar Filgrastrim and blood stem cell transplant (22M)

I am part of a registry for bone marrow and blood stem cells (nmdp if you're curious). I was matched for a blood stem cell transplant. I am just a little bit concerned about filgrastrim, I know everything I read says it's safe for people who don't have cancer but I still feel weird about it for some reason (haven't had my first shot yet). As for the transplant itself, I'm not particularly worried about though I did read in my forms about the possibility of a central line surgery. I'm nervous about getting that too though it shouldn't be likely since I have had surgery (wisdom teeth surgery to be specific) in the past with stuff in my veins and there wasn't any problem. My main concern is the fact that I'm overweight and that I cracked my head open as a kid but it fully healed and I don't think I got any brain damage from it. One last thing, I haven't my pre surgery check up and vein assessment yet, that will be this Tuesday.
Let me know if my concerns are valid.
Thank you.
Other information: Height: 5'8.75"
Weight: 233 lb
Race: White (Not Hispanic or Latino)
Medical issues: Overweight
Drink: Yes (small amount of red wine at church once a month)
Smoke/Vape: No
Recreational drugs: No
submitted by realdavidguitar to AskDocs [link] [comments]


2024.05.30 20:39 IrinaSophia The File for the Canonization of Eldress Makaria of Mount Amomon Has Been Submitted

According to the exclusive information of ope.gr and the journalist Demetrios Stroumbakos, Metropolitan Kyrillos of Kifissia, Amarousi, Oropou and Marathon submitted a file to the Holy Synod of the Church of Greece which contains the information regarding the Canonization of Eldress Makaria Desypris, who was the one who discovered the Sacred Relic of Saint Ephraim of Nea Makri in January 1950.
This morning (May 30, 2024) the Metropolitan officiated at the Monastery of Saint Ephraim, on the occasion of the joyous event of the deposit of the file for the canonization of Eldress Makaria, which will then be transferred from the Holy Synod of the Church of Greece to the Ecumenical Patriarchate.
Eldress Makaria of Mount Amomon (1911-1999)
Eldress Makaria (in the world known as Margarita Desypris) was born on March 12, 1911 in the village of Falatados in Tinos. When she turned nineteen she made the decision to become a nun. During the German Occupation, she went to the Averof women's prison in Athens and there she lovingly cared for the prisoners' children. In 1945, she visited the then stavropegic men's monastery on Mount Amomon, where she lived amidst its ruins for several years under difficult conditions. There her health was tested many times. She slept in the ruins of the monastery, without windows or coverings and endured every ordeal.
By divine impulse, she built a cell there and began to clear the ruins of the old temple to rebuild it. Many times she contemplated how monks had lived in that place over the centuries and she prayed that one of them would appear to her. A voice, at first silent but with time growing louder in her soul, told her: "Dig and you will find what you desire," until the moment a spot was revealed to her in the courtyard of the monastery
On January 3, 1950 she commissioned a laborer to dig the specific spot that her own soul indicated to her. Although the laborer was negative and wanted to dig anywhere but at this spot, finally, after pleas and prayers, the laborer was convinced and began to dig. The site had a half-demolished fireplace, wall and things that indicated that there had once been a monk's cell there. The first find was a skull. In fact, the place emanated with a wonderful fragrance.
"I knelt with reverence and embraced the Saint's relic and deeply felt the extent of his martyrdom. My soul was filled with joy, I acquired a great treasure, and taking the soil with care I saw the harmony of its setting, which, despite so many centuries in the earth, had not changed," wrote Eldress Makaria, describing the shocking things that happened to her.
Carefully, the Abbess Makaria took out the whole relic and placed it in a box that was above the grave. It was obvious that he was a clergyman as his cassock had remained intact.
In the evening, while reading Vespers, Eldress Makaria heard footsteps. The sound came from the grave, echoing to the church door. That's where she first saw him. He was tall with small round eyes, with a long black beard that reached his neck, dressed in the monastic garb. In one hand he had a flame and with the other he was blessing. He asked to be taken out of the box they had him in. The very next day the Abbess cleaned the bones and placed them in a box in the Sanctuary of the temple.
That same night, the Saint appeared in her sleep, thanked her and revealed his name: Ephraim. The relic of Saint Ephraim has been kept there since then and every day hundreds of believers visit it asking the Saint for his blessing and help. The Saint, by the grace of God, has performed thousands of miracles. In the vicinity of the Monastery, and protected by a building built around it, there is the mulberry tree on which Saint Ephraim breathed his last.
Without financial resources, until 1980 Abbess Makaria maintained an orphanage with approximately 70 school-age children, to whom she provided shelter, food, clothing and an elementary level education, from which some went on to Higher Educational Institutions.
Although she did not have a University education, she published Patristic texts, "Ascetic Discourses of Basil the Great" and compiled a Supplicatory Canon and Akathist to Saint Ephraim, whom she loved very much. She also recorded and gradually published in sixteen volumes the miracles of Saint Ephraim for the support and encouragement of the faithful.
After partaking of the Immaculate Mysteries her soul ascended to the Heavens. It was Friday, the feast of Saint George the Trophy-Bearer, April 23rd 1999.
Today, her sacred relic lies in the secluded tomb that she herself had dug years ago in the forecourt of the Monastery of which, by the grace of God, she was Founder and Abbess for half a century.
According to the exclusive information of ope.gr and the journalist Demetrios Stroumbakos, Metropolitan Kyrillos of Kifissia, Amarousi, Oropou and Marathon submitted a file to the Holy Synod of the Church of Greece which contains the information regarding the Canonization of Eldress Makaria Desypris, who was the one who discovered the Sacred Relic of Saint Ephraim of Nea Makri in January 1950.
This morning (May 30, 2024) the Metropolitan officiated at the Monastery of Saint Ephraim, on the occasion of the joyous event of the deposit of the file for the canonization of Eldress Makaria, which will then be transferred from the Holy Synod of the Church of Greece to the Ecumenical Patriarchate.
Source
submitted by IrinaSophia to OrthodoxGreece [link] [comments]


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