Chronic doxycyclin therapy
Topics in Physical Therapy
2012.02.10 07:33 Topics in Physical Therapy
If you are not a licensed PT or currently under the care of a PT please do not post here. This is a sub for practicing physical therapists to discuss cases, research, old and new tricks, or other therapy-relevant topics. Requests for advice or education regarding your personal health issues will be removed and you may be banned. These questions should be discussed directly with your physical therapist.
2020.05.18 15:00 blueboy840 chronicpainrelief
this is a community to share how you improve your quality of life with a disability or chronic illness. discussions such as adaptive exercise, aids, occupational and physical therapy, will take place. I want to share information and my experiences with red light therapy, pulsed electromagnetic field therapy, cryotherapy, hyperbaric oxygen therapy, acupuncture, biofeedback, massage, and yoga for pain relief.
2019.11.22 20:08 MysticalPixels PainManagment
This community's focus is the managing chronic pain with the use of medications, therapy, alternatives, exercise, surgury and mental well being. We discuss issues such as the opioid crisis and how it has affected us. We share experiences with dealing with medical professionals, pain treatment centers, even drug rehabilitation. We try to focus on recovery and seek the experiences of others that we might help ourselves. Disability is not a crime, nor welfare. We try to shift from self to service.
2024.06.01 12:13 The_Dadditor Avoiding negativity
Hi all,
I have been 'officially' diagnosed with depression caused by chronic illness a few days ago, which isn't really news to me. Anyway I'm in therapy in the same hospital I work at, and I'm happy with my therapist as there's a good connection between us.
One of the first things I'm supposed to work on would be to avoid negativity and focus on the things that make me happy right now, even if they're not productive.
I find this difficult as I'm a massive fan of movies, TV and quality storylines in games. I already find it more difficult to get the same enjoyment from them as I did before. And now recently every online discussion about new releases is way more negative. Even if in some cases people enjoyed everything about the content, they find something bad to say about the production, writers, delays or even finances.
Now avoiding online discussion would be one thing but these opinions so far always bleed into real life discussions. I really don't want to unintentionally adopt this unending cycle of negativity but enjoying something all alone makes me sad too.
Other things I enjoy are so far really difficult because of my chronic illness.
I guess there's no real question or answer here but at least I got that off my chest. I wish you all the best of health and a great day.
submitted by The_Dadditor to depression [link] [comments]
I have been 'officially' diagnosed with depression caused by chronic illness a few days ago, which isn't really news to me. Anyway I'm in therapy in the same hospital I work at, and I'm happy with my therapist as there's a good connection between us.
One of the first things I'm supposed to work on would be to avoid negativity and focus on the things that make me happy right now, even if they're not productive.
I find this difficult as I'm a massive fan of movies, TV and quality storylines in games. I already find it more difficult to get the same enjoyment from them as I did before. And now recently every online discussion about new releases is way more negative. Even if in some cases people enjoyed everything about the content, they find something bad to say about the production, writers, delays or even finances.
Now avoiding online discussion would be one thing but these opinions so far always bleed into real life discussions. I really don't want to unintentionally adopt this unending cycle of negativity but enjoying something all alone makes me sad too.
Other things I enjoy are so far really difficult because of my chronic illness.
I guess there's no real question or answer here but at least I got that off my chest. I wish you all the best of health and a great day.
2024.06.01 10:47 Ringostarfox Turned 30 and I feel so lost
I just have no idea what I want to do with my life.
I have autism, adhd, anxiety, depression, ocd, cptsd, a painful spinal deformity, and chronic long inflammation. I went to school for music production, but the market is so flooded it feels impossible to get in anywhere, especially when networking is so key, but also so difficult for me. I try talking to people at shows and I can barely hear them over the chatter and background music, or they sense my anxiety or something. I try reaching out to people and studio and live venues to help them mix and master stuff or run audio and I just can't get it to happen enough to make it a career. It's the only thing I'm good at and brings me joy, but I can't make it work even after trying for almost 15 years.
Even my side passions: article writing, graphic design, photo restoration. It's all been corrupted even further by AI. Can't even rely on those for minor sources of income anymore.
All the "actual" jobs I work burn me out and I have to quit because my health problems get so bad, but doctors and pretty much everyone says I shouldn't go on disability. That it would limit what I can do. But I can barely do anything anymore. No job that wouldn't bother my conditions will hire me, I don't have a car and don't like driving anyways so those jobs are out of the question, I'm very bad at social media promotion so content creation has been tough. People say to try caregiving but it makes me nervous because I can barely regulate my own life.
Friends and family have to help me a lot financially, and I feel like an over-privileged PoS, and I can't even raise myself up with my support network. Might have to move back in with my parents, but we have a troubled relation despite them helping me out. It's hard not to feel like a failure. I don't know... I've done therapy, I'm on medication, I have a loving relation. Why can't I be happy?
submitted by Ringostarfox to autism [link] [comments]
I have autism, adhd, anxiety, depression, ocd, cptsd, a painful spinal deformity, and chronic long inflammation. I went to school for music production, but the market is so flooded it feels impossible to get in anywhere, especially when networking is so key, but also so difficult for me. I try talking to people at shows and I can barely hear them over the chatter and background music, or they sense my anxiety or something. I try reaching out to people and studio and live venues to help them mix and master stuff or run audio and I just can't get it to happen enough to make it a career. It's the only thing I'm good at and brings me joy, but I can't make it work even after trying for almost 15 years.
Even my side passions: article writing, graphic design, photo restoration. It's all been corrupted even further by AI. Can't even rely on those for minor sources of income anymore.
All the "actual" jobs I work burn me out and I have to quit because my health problems get so bad, but doctors and pretty much everyone says I shouldn't go on disability. That it would limit what I can do. But I can barely do anything anymore. No job that wouldn't bother my conditions will hire me, I don't have a car and don't like driving anyways so those jobs are out of the question, I'm very bad at social media promotion so content creation has been tough. People say to try caregiving but it makes me nervous because I can barely regulate my own life.
Friends and family have to help me a lot financially, and I feel like an over-privileged PoS, and I can't even raise myself up with my support network. Might have to move back in with my parents, but we have a troubled relation despite them helping me out. It's hard not to feel like a failure. I don't know... I've done therapy, I'm on medication, I have a loving relation. Why can't I be happy?
2024.06.01 10:35 drdeepeshkalra What is Renal Cancer ?
 | Renal cancer, also known as kidney cancer, occurs when cells in the kidney grow uncontrollably, forming a tumor. The kidneys, located in the back of the abdomen, are vital organs responsible for filtering waste and excess fluids from the blood, producing urine, and regulating electrolyte balance. Renal cancer can affect one or both kidneys and may spread to other parts of the body if left untreated. submitted by drdeepeshkalra to u/drdeepeshkalra [link] [comments] Symptoms of Renal Cancer
The Role of a Kidney DoctorA kidney doctor, or nephrologist, is a medical specialist trained in the diagnosis and treatment of kidney disorders, including renal cancer. While nephrologists primarily focus on managing conditions like chronic kidney disease and hypertension, they also play a vital role in the comprehensive care of patients with renal cancer.Here’s how a kidney doctor can help: 1. Diagnosis: A nephrologist can evaluate your symptoms, order diagnostic tests such as blood tests, urine tests, imaging studies (like CT scans or MRIs), and biopsies to confirm the presence of renal cancer and determine its stage. 2. Treatment Planning: Once diagnosed, a kidney doctor collaborates with other specialists, such as oncologists and surgeons, to develop a personalized treatment plan tailored to your specific needs. Treatment options for renal cancer may include surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy, or a combination of these approaches. 3. Monitoring and Follow-Up: After treatment, a nephrologist monitors your progress, manages any side effects or complications, and conducts regular follow-up appointments to ensure the cancer remains under control and to address any new concerns that may arise. 4. Supportive Care: Throughout your cancer journey, a kidney doctor provides ongoing support, guidance, and education to help you navigate the physical and emotional challenges associated with renal cancer and its treatment. ConclusionRenal cancer is a serious condition that requires prompt medical attention and comprehensive care. If you’re experiencing symptoms suggestive of kidney cancer, don’t hesitate to consult a kidney doctor for evaluation and treatment. Early detection and intervention can significantly improve outcomes and quality of life for individuals with renal cancer. Remember, your health is your most valuable asset — take proactive steps to protect it. |
2024.06.01 10:04 Old_Criticism1697 I (20f) made a mistake that bordered on disloyal. How can I help my boyfriend (21m) feel more secure?
Tldr: in a situation where i felt pressure, i nearly left someone my phone number (family members insisting because they wanted me to be spontaneous while im young kind of thing, mixed with bad social anxiety). i wrote it down, left it to be found, but immediately came back for it and discarded it. I explained to my boyfriend when i got home and he seemed to understand, but i want to make sure he knows how much i love him. I feel so sick thinking that he might be feeling unwanted. How can i help him feel appreciated and secure?
I want to preface my further context with the establishment that none of it makes it any better, but provides some insight regarding my intentions and circumstances.
I was out at dinner with some family members who can get rowdy and intense, both of which are in unhappy marriages. I love my boyfriend dearly, we’ve been together for 9 months. They started on the topic of me being young how i need to be impulsive, and that turned into telling me i should leave my number behind for the waiter, “just to see what happens”. I resisted, but i did cave.
(I have severe social anxiety and am autistic and i’m subsequently a chronic people pleaser. This is something im working on in therapy but i didnt realize how much more i needed to focus on it and will be doing so going forward. Its something i never realized could affect other people and their trust in me)
Basically, they were projecting, they didnt want me to be stuck in one place like they feel they are. Me taking an opportunity was exciting for them, and i didnt want to dampen the energy or make them upset with me. I had no intentions of answering if someone did text, and i wrote it so they would stop. But, avoiding an uncomfortable interaction matters so so much less than my boyfriend’s emotions and trust in me. I wrote the number down, but turned right around and threw it out. I shouldnt have written it down in the first place.
As soon as i got home, i told him what happened. He understands how bad i handle peer pressure and affirmed that he knows i had no intentionality and he isnt worried about disloyalty, especially given that i came right to him with it (but of course it still made him feel uncomfortable). I just am not sure how to approach moving forward. How can i help make him feel more secure? Is he being too gentle with me?
submitted by Old_Criticism1697 to relationship_advice [link] [comments]
I want to preface my further context with the establishment that none of it makes it any better, but provides some insight regarding my intentions and circumstances.
I was out at dinner with some family members who can get rowdy and intense, both of which are in unhappy marriages. I love my boyfriend dearly, we’ve been together for 9 months. They started on the topic of me being young how i need to be impulsive, and that turned into telling me i should leave my number behind for the waiter, “just to see what happens”. I resisted, but i did cave.
(I have severe social anxiety and am autistic and i’m subsequently a chronic people pleaser. This is something im working on in therapy but i didnt realize how much more i needed to focus on it and will be doing so going forward. Its something i never realized could affect other people and their trust in me)
Basically, they were projecting, they didnt want me to be stuck in one place like they feel they are. Me taking an opportunity was exciting for them, and i didnt want to dampen the energy or make them upset with me. I had no intentions of answering if someone did text, and i wrote it so they would stop. But, avoiding an uncomfortable interaction matters so so much less than my boyfriend’s emotions and trust in me. I wrote the number down, but turned right around and threw it out. I shouldnt have written it down in the first place.
As soon as i got home, i told him what happened. He understands how bad i handle peer pressure and affirmed that he knows i had no intentionality and he isnt worried about disloyalty, especially given that i came right to him with it (but of course it still made him feel uncomfortable). I just am not sure how to approach moving forward. How can i help make him feel more secure? Is he being too gentle with me?
2024.06.01 09:38 working-thru-traumas Did I experience COCSA AND CSA?
I (fem) grew up in a family full of girls. When I was younger, my cousin, 2 years older than me, would have my other cousin and I play "boyfriend and girlfriend". We would take turns being her "boyfriend". We would dry hump and grind on each other. I can't recall how old we were specifically, but it was definitely around elementary school. This would happen more than once and it never was forced on us. It then would continue between me and my sister who is 2 years younger than me. We would roleplay made up stories and pretend to be each other's crush. I don't recall how this started and it went on for years. All while this was happening, I was exposed to porn at a very early age and had a male adult cousin (18 years older) who lived with us at the time and was grooming me. He would say all the time about how he wished he could marry me. From what I can remember, he had me sit on top of him while we were both clothed and grinded on me. At that time, I didn't know it was wrong and never felt "abused" because he was the "cool" cousin. I never told my parents and he left our house not too long after that. Now that I'm an adult, I can see what he did was beyond inappropriate and my experiences led me to be hypersexual.
submitted by working-thru-traumas to CPTSD [link] [comments]
- Is what happened to me with my adult cousin considered sexual assault or molestation? There was never any penetration but he used my body, even if it was just sitting on top of his lap, to fulfill his sexual need.
- Am I a victim and a perpetrator of COCSA and incest? I feel so shameful. We both sought it out but I feel to blame because I am older. This hasn't affected our relationship negatively as we are close to this day and confide in one another. We haven't brought this up since we stopped because we were old enough to know it was wrong. We both struggle with mental health and family dysfunction from my parents abandoning us to raise our younger brothers (10&12) when we turned 18. I'm currently in therapy now to talk about the abandonment situation and chronic fatigue. I have no idea how to bring all of this up with my therapist.
2024.06.01 09:31 awalkinthepark1111 Very odd eye/confusion issue…
Something weird has happened as of tonight twice now and I think I know what it is but I want to ask around in case I’m wrong.
My cat is 15, always had kidney elevation but kidneys are doing good have went down as of now numbers got better. Blood work and stuff done less than 2 months ago all is great. She just had a UTI gets them a couple times a year. She has just insisted in getting the tiny tasters duck food and won’t touch anything else now but loves it. Exams and everything are great. Active and would never know she’s 15. She weighs 9.33lbs.
She takes one fourth Pepcid every night, I give her d-mannose powder once daily for her chronic UTIs and liquid b-12 as often as I remember.
She always takes doxycycline for her UTIs. Always liquid. This past time 2 weeks ago we tried the pill. At the same time she decided to start sleeping in our shower which she’s never really done before. We’re on the second story and the woman under us is very questionable, we will say that.
One night on the antibiotics she was sleeping in the shower and started howling and trying to find me, she’s walking around and acting like she can’t see anything. She’s bumping into things and I mean it’s scaring the crap out of her. Touch her and she jumps sky high. Pick her up and hold her in the light her eyes were just pitch black no color anywhere and they didn’t constrict or anything in the light. Put her down and she hits the floor like doesn’t even put her legs out. I called ER, they said it’s fine unless she has breathing issues or fever. It lasted maybe 10 mins and she went back to normal.
I got her in immediately the next day with the vet and they did all the tests - her eyes are totally fine no damage. Blood pressure totally normal. I switched her to the liquid doxy again just in case since she never had an issue on the liquid. And yea she has been to a cardiologist the last year because of a heart murmur just to check everything and it all looks great.
It’s been two weeks, and that happened AGAIN tonight. Not on the medicine anymore. BUT she was again sleeping in that shower. For quite awhile. Since that happened she hasn’t spent too much time in there,until tonight. Just this past Tuesday she had a recheck and they did her blood pressure and eyes again just to triple check and make sure and she was absolutely fine. All good.
We are thinking there’s some kind of gas or something coming up in that shower and it’s making her high or something. There’s literally no other explanation. No new meds or anything. My partner picked up a cloth that was over the drain and said it smelt horrible like chemicals and says that’s gatta be it. There will be no more shower sleeping for her.
She’s been eating normal, no vomiting, no sneezing no coughing literally no other things happening that would seem alarming.
Has anyone else ever had anything like that happen? It’s so weird. It has only happened when she’s spent a significant amount of time in that shower at night.
submitted by awalkinthepark1111 to AskVet [link] [comments]
My cat is 15, always had kidney elevation but kidneys are doing good have went down as of now numbers got better. Blood work and stuff done less than 2 months ago all is great. She just had a UTI gets them a couple times a year. She has just insisted in getting the tiny tasters duck food and won’t touch anything else now but loves it. Exams and everything are great. Active and would never know she’s 15. She weighs 9.33lbs.
She takes one fourth Pepcid every night, I give her d-mannose powder once daily for her chronic UTIs and liquid b-12 as often as I remember.
She always takes doxycycline for her UTIs. Always liquid. This past time 2 weeks ago we tried the pill. At the same time she decided to start sleeping in our shower which she’s never really done before. We’re on the second story and the woman under us is very questionable, we will say that.
One night on the antibiotics she was sleeping in the shower and started howling and trying to find me, she’s walking around and acting like she can’t see anything. She’s bumping into things and I mean it’s scaring the crap out of her. Touch her and she jumps sky high. Pick her up and hold her in the light her eyes were just pitch black no color anywhere and they didn’t constrict or anything in the light. Put her down and she hits the floor like doesn’t even put her legs out. I called ER, they said it’s fine unless she has breathing issues or fever. It lasted maybe 10 mins and she went back to normal.
I got her in immediately the next day with the vet and they did all the tests - her eyes are totally fine no damage. Blood pressure totally normal. I switched her to the liquid doxy again just in case since she never had an issue on the liquid. And yea she has been to a cardiologist the last year because of a heart murmur just to check everything and it all looks great.
It’s been two weeks, and that happened AGAIN tonight. Not on the medicine anymore. BUT she was again sleeping in that shower. For quite awhile. Since that happened she hasn’t spent too much time in there,until tonight. Just this past Tuesday she had a recheck and they did her blood pressure and eyes again just to triple check and make sure and she was absolutely fine. All good.
We are thinking there’s some kind of gas or something coming up in that shower and it’s making her high or something. There’s literally no other explanation. No new meds or anything. My partner picked up a cloth that was over the drain and said it smelt horrible like chemicals and says that’s gatta be it. There will be no more shower sleeping for her.
She’s been eating normal, no vomiting, no sneezing no coughing literally no other things happening that would seem alarming.
Has anyone else ever had anything like that happen? It’s so weird. It has only happened when she’s spent a significant amount of time in that shower at night.
2024.06.01 09:22 TheDesertGem Cortisol is destroying my physical and mental health
I got some lab work done recently because I’ve been mentally suffering for the past year or so and my results showed an EXTREMELY high cortisol level. The doctor was genuinely concerned and wants me to try things like Zinc, Magnesium, vitamins D&A, fish oil, and weekly therapy to help manage but I’d like to try something alternative/stronger. My cortisol is so high it’s causing thyroid dysfunction and I was told I’d be developing an autoimmune disease within the next few years at this rate if I can’t calm down. It’s also contributing to chronic tissue inflammation and a series of other imbalances, and ironically this is just making me stress out more, like to the point I feel like I’m losing my mind. I sleep plenty, I eat healthy, I’m a physically fit/active 140lb 5’6” 20yo I just don’t know how this could happen. I was also told I severely lacked in testosterone and creatinine levels and that could be potentially adding to the extreme stress factor and chronic fatigue, so I was put on a hormone stimulant (not exactly sure what it is) as well as daily creatine to replace what should be my natural levels. Please any advice is appreciated, I’ve lived like this for years now.
submitted by TheDesertGem to Supplements [link] [comments]
2024.06.01 09:15 kyyface Found out my grandma likely had this disorder, it’s bringing up so much & idk how to make sense of it.
She died last May (in a very odd way, I’ll get to that later), and since then so much has been coming to light.
I’m going to call my mom “R” and my grandma “E”.
• R thought she had a tumour in her brain until she was 40 years old, when she called the children’s hospital (whom she described had “experimented” on her, which turned out to be all E’s doing) and they told her they didn’t find anything wrong based on what E said, but that R did have severe ADHD, which she was never aware of. Obviously this affected her deeply, but not in the ways E claimed; which was essentially brain damage, among other things.
• R had me as a teen so E has always had control over us. For as long as I can remember I’ve been “sick”. As a child I felt in my heart that I wasn’t going to live long. I was always in the hospital, on meds, getting scans, pokes, tests; you name it. And I, to this day, have no idea why. I’ve been healthy since I left home. Mentally, I’m a wreck. But I have a shit ton of trauma. My therapist has suggested that the “health issues” I remember experiencing as a kid were likely the effect of high cortisol and adrenaline. Along with “cult-like” manipulation tactics.
• I am diagnosed with CPTSD, OCD, ASD, and ADHD. I also struggle with chronic panic attacks and health anxiety.
• E was a social worker and specialized in psych. I remember her pouring over the DSM, and proudly armchair diagnosing and lording her knowledge over people. I remember one time she told me about Munchausen by Proxy, and she was fascinated by it. It’s burned into my brain. I’d find myself reliving that moment and remembering the light in her eyes as she explained it. When I found out she likely had this disorder my blood ran cold and that moment flashed back. It’s crazy to think my nervous system has been trying to tell me all this time.
• Further to the last point, E knew R and I were neurodivergent; I suspect my great grandma was as well, and E hated her mother for being “ditsy” and “messy”. Which is partly why I think she tried to manipulate us. I stopped talking to E two years ago because I found out, after a lot of therapy (which she disapproved of) that I had all these undiagnosed mental conditions. AND SHE KNEW. I had been assessed at a young age by a friend of hers (she could pull all the strings being in her profession, it was a small town, and she was highly esteemed) and I tested highly for ASD. E somehow covered it up, and I didn’t find out until I was 27. What’s worse is she forced me to mask by essentially experimenting on my brain with various therapy techniques and fear tactics so I didn’t get noticed and diagnosed. This also made me enthralled to her because I needed her constant reinforcement to function “correctly”.
• E taught me to be constantly afraid for my health and of other people. I wasn’t to trust the government, the police, or any healthcare professionals. She even deliberately put rifts between me and friends/boyfriends. She did the same to R.
• I was on certain medications for years for no reason. She especially enjoyed giving suppositories. She forced me to take Advil all the time; the huge extra strength ones, and I’d cry and try to get away, screaming I don’t have a headache. And she forced it into my mouth and held my mouth and nose until I swallowed. I have severe anxiety taking medicine to this day.
• E told me I had asthma, underdeveloped lungs, chronic infections, tooth decay, and various autoimmune disorders. Anytime I got sick with a cold she told me I’d die. During H1N1 she told me I was definitely going to get it and die, so I spent most of that year in the hospital. She constantly took me to the dentist for various unnecessary procedures. I have no idea how it was allowed. By the time I was 19 none of my back teeth were intact, and when I moved and got my own dentist they were shocked and asked many questions. I told them I had soft teeth and I always had to get them fixed - to which they said tooth softness is a temporary state... I nearly fell over. I still don’t know how to process it. Because of all the intervention my teeth cause me a lot of issues to this day.
• Once I became an adult and moved out, E started to lose control of R and I. She became more and more sick herself, which caused R and I to run to her rescue. She was always having the craziest things happen to her. Heart attacks, severe infections, severe pain, injuries such as falls and deep cuts. For almost 5 years she was in the hospital every other week. During the height of Covid she told me the hospital put her in the Covid ward by accident and gave her Covid. I was enraged because myself, my partner, and my little sister had visited her, allegedly in the Covid ward. I was going to write a scathing letter to all the appropriate boards, and suddenly E turned tail and said “that’s not what happened”. It floored me. That same year I caught her in a heart attack lie, which made me remember the first one she had where no doctor could figure out what was wrong with her and I remember fighting with the doctor out of confusion and desperation asking why no one would help her… and I remember the pained look he gave me…
• I started putting the pieces together a few years before E died, and I just removed myself more and more, and the sicker she got, and the more crazy the situations. She starting sending relatives to reach me, and she’d tell them she was dying, so they would go to every effort to reach me - and not understand why I wouldn’t respond. She even convinced nurses and careaids to track me down. When that didn’t work, she started overdosing herself. Which was real, and scary. Unfortunately R got dragged in, and it broke her irreparably.
• Last May E overdosed and ended up in long-term care. She had a stroke and then lost control of her hands. She was so damaged by this point, and no one would take her on, so she was put in palative. She was there two weeks. Then she put a DNR in place. The next day was Friday, and sometime in the evening they suspect she had another stroke, right when no one was around, and she wasn’t found until a day later. They couldn’t do any tests because of the DNR or help her recover. The doctors never gave me a straight answer, and the whole thing wreaked of what I’ve been going thru these past years. E left us all the nastiest messages you’ve ever heard just before, and unfortunately my little sister listened to hers.
• My mom, R, died two month later of an overdose. I know E is at fault. She did this to us. I’ll never know what happened in those last few months they were together, I only have little bits and bobs of pure chaos - during which time R lost her house, all her belongings, and ended up on the street.
I really don’t know how one recovers from all of this. Not enough is known about this disorder and it’s victims. I’m in trauma therapy, but there’s too much, and no one can really know this form of evil unless they’ve experienced it. I’ve never put this all out there like is this, I dont know what to expect or what I hope to gain. Maybe just understanding. Thank you if you read it all.
submitted by kyyface to Munchausensyndrome [link] [comments]
I’m going to call my mom “R” and my grandma “E”.
• R thought she had a tumour in her brain until she was 40 years old, when she called the children’s hospital (whom she described had “experimented” on her, which turned out to be all E’s doing) and they told her they didn’t find anything wrong based on what E said, but that R did have severe ADHD, which she was never aware of. Obviously this affected her deeply, but not in the ways E claimed; which was essentially brain damage, among other things.
• R had me as a teen so E has always had control over us. For as long as I can remember I’ve been “sick”. As a child I felt in my heart that I wasn’t going to live long. I was always in the hospital, on meds, getting scans, pokes, tests; you name it. And I, to this day, have no idea why. I’ve been healthy since I left home. Mentally, I’m a wreck. But I have a shit ton of trauma. My therapist has suggested that the “health issues” I remember experiencing as a kid were likely the effect of high cortisol and adrenaline. Along with “cult-like” manipulation tactics.
• I am diagnosed with CPTSD, OCD, ASD, and ADHD. I also struggle with chronic panic attacks and health anxiety.
• E was a social worker and specialized in psych. I remember her pouring over the DSM, and proudly armchair diagnosing and lording her knowledge over people. I remember one time she told me about Munchausen by Proxy, and she was fascinated by it. It’s burned into my brain. I’d find myself reliving that moment and remembering the light in her eyes as she explained it. When I found out she likely had this disorder my blood ran cold and that moment flashed back. It’s crazy to think my nervous system has been trying to tell me all this time.
• Further to the last point, E knew R and I were neurodivergent; I suspect my great grandma was as well, and E hated her mother for being “ditsy” and “messy”. Which is partly why I think she tried to manipulate us. I stopped talking to E two years ago because I found out, after a lot of therapy (which she disapproved of) that I had all these undiagnosed mental conditions. AND SHE KNEW. I had been assessed at a young age by a friend of hers (she could pull all the strings being in her profession, it was a small town, and she was highly esteemed) and I tested highly for ASD. E somehow covered it up, and I didn’t find out until I was 27. What’s worse is she forced me to mask by essentially experimenting on my brain with various therapy techniques and fear tactics so I didn’t get noticed and diagnosed. This also made me enthralled to her because I needed her constant reinforcement to function “correctly”.
• E taught me to be constantly afraid for my health and of other people. I wasn’t to trust the government, the police, or any healthcare professionals. She even deliberately put rifts between me and friends/boyfriends. She did the same to R.
• I was on certain medications for years for no reason. She especially enjoyed giving suppositories. She forced me to take Advil all the time; the huge extra strength ones, and I’d cry and try to get away, screaming I don’t have a headache. And she forced it into my mouth and held my mouth and nose until I swallowed. I have severe anxiety taking medicine to this day.
• E told me I had asthma, underdeveloped lungs, chronic infections, tooth decay, and various autoimmune disorders. Anytime I got sick with a cold she told me I’d die. During H1N1 she told me I was definitely going to get it and die, so I spent most of that year in the hospital. She constantly took me to the dentist for various unnecessary procedures. I have no idea how it was allowed. By the time I was 19 none of my back teeth were intact, and when I moved and got my own dentist they were shocked and asked many questions. I told them I had soft teeth and I always had to get them fixed - to which they said tooth softness is a temporary state... I nearly fell over. I still don’t know how to process it. Because of all the intervention my teeth cause me a lot of issues to this day.
• Once I became an adult and moved out, E started to lose control of R and I. She became more and more sick herself, which caused R and I to run to her rescue. She was always having the craziest things happen to her. Heart attacks, severe infections, severe pain, injuries such as falls and deep cuts. For almost 5 years she was in the hospital every other week. During the height of Covid she told me the hospital put her in the Covid ward by accident and gave her Covid. I was enraged because myself, my partner, and my little sister had visited her, allegedly in the Covid ward. I was going to write a scathing letter to all the appropriate boards, and suddenly E turned tail and said “that’s not what happened”. It floored me. That same year I caught her in a heart attack lie, which made me remember the first one she had where no doctor could figure out what was wrong with her and I remember fighting with the doctor out of confusion and desperation asking why no one would help her… and I remember the pained look he gave me…
• I started putting the pieces together a few years before E died, and I just removed myself more and more, and the sicker she got, and the more crazy the situations. She starting sending relatives to reach me, and she’d tell them she was dying, so they would go to every effort to reach me - and not understand why I wouldn’t respond. She even convinced nurses and careaids to track me down. When that didn’t work, she started overdosing herself. Which was real, and scary. Unfortunately R got dragged in, and it broke her irreparably.
• Last May E overdosed and ended up in long-term care. She had a stroke and then lost control of her hands. She was so damaged by this point, and no one would take her on, so she was put in palative. She was there two weeks. Then she put a DNR in place. The next day was Friday, and sometime in the evening they suspect she had another stroke, right when no one was around, and she wasn’t found until a day later. They couldn’t do any tests because of the DNR or help her recover. The doctors never gave me a straight answer, and the whole thing wreaked of what I’ve been going thru these past years. E left us all the nastiest messages you’ve ever heard just before, and unfortunately my little sister listened to hers.
• My mom, R, died two month later of an overdose. I know E is at fault. She did this to us. I’ll never know what happened in those last few months they were together, I only have little bits and bobs of pure chaos - during which time R lost her house, all her belongings, and ended up on the street.
I really don’t know how one recovers from all of this. Not enough is known about this disorder and it’s victims. I’m in trauma therapy, but there’s too much, and no one can really know this form of evil unless they’ve experienced it. I’ve never put this all out there like is this, I dont know what to expect or what I hope to gain. Maybe just understanding. Thank you if you read it all.
2024.06.01 08:54 RambosCollectibles Not sure who to go with in New York
I have some crazy chronic pain and i think i would really benefit from ketamine treatment.
i like joyous, but im scared its going to be too low dose
Better U looks interesting
i live in new york
Can anyone give me some advice, for the cheapest , ketamine in NY? I do not really need therapy, i already have a therapist , if that can reduce the cost..
submitted by RambosCollectibles to TherapeuticKetamine [link] [comments]
i like joyous, but im scared its going to be too low dose
Better U looks interesting
i live in new york
Can anyone give me some advice, for the cheapest , ketamine in NY? I do not really need therapy, i already have a therapist , if that can reduce the cost..
2024.06.01 08:37 ace_hospital_pune How Thyroid Disorders Impact Kidney and Urinary Tract Health ?
 | https://preview.redd.it/iht2w6isnw3d1.png?width=1280&format=png&auto=webp&s=390eaa4459ad6978478d5a190566069a7004b86a submitted by ace_hospital_pune to u/ace_hospital_pune [link] [comments] Introduction: In the complex and interconnected world of human physiology, the thyroid gland holds a place of great importance. This small, butterfly-shaped gland located in the neck is responsible for producing hormones that regulate metabolism, growth, and development. While the thyroid's role in these processes is well-known, its impact on other organs, particularly the kidneys and the urinary tract, is often overlooked. In this blog, we will explore the intricate relationship between thyroid disorders and kidney and urinary tract functions, highlighting the importance of holistic healthcare approaches in managing these conditions. Understanding the Thyroid Gland The thyroid gland produces two main hormones: thyroxine (T4) and triiodothyronine (T3). These hormones influence nearly every cell in the body, affecting metabolic rate, heart function, digestive health, muscle control, brain development, and bone maintenance. The production and release of these hormones are regulated by the pituitary gland, which secretes thyroid-stimulating hormone (TSH). Common Thyroid Disorders Thyroid disorders are relatively common and can significantly impact overall health. The two primary types of thyroid disorders are: Hypothyroidism: This condition occurs when the thyroid gland does not produce enough thyroid hormones. Symptoms include fatigue, weight gain, cold intolerance, depression, and slowed heart rate. Hashimoto's thyroiditis, an autoimmune disorder, is a common cause of hypothyroidism. Hyperthyroidism: This condition occurs when the thyroid gland produces too much thyroid hormone. Symptoms include weight loss, rapid heartbeat, sweating, nervousness, and irritability. Graves' disease, another autoimmune disorder, is a common cause of hyperthyroidism. The Thyroid-Kidney Connection The kidneys play a crucial role in filtering blood, removing waste products, balancing electrolytes, and regulating blood pressure. Thyroid hormones influence kidney function in several ways, and disruptions in thyroid hormone levels can have significant effects on kidney health. Hypothyroidism and Kidney Function Hypothyroidism can lead to several kidney-related issues, including: Reduced Glomerular Filtration Rate (GFR): GFR is a measure of how well the kidneys filter blood. Hypothyroidism can reduce GFR, leading to impaired kidney function and decreased clearance of waste products from the body. This can result in the accumulation of toxins and fluids. Hyponatremia: Hypothyroidism can cause an imbalance in sodium levels, leading to hyponatremia (low sodium levels in the blood). This condition can cause symptoms such as headache, nausea, confusion, and seizures. Proper sodium balance is crucial for maintaining kidney function. Fluid Retention and Edema: Hypothyroidism can cause the body to retain fluids, leading to swelling (edema) in the extremities. This fluid retention can put additional strain on the kidneys and exacerbate kidney dysfunction. Hyperthyroidism and Kidney Function Hyperthyroidism can also affect kidney health, leading to issues such as: Increased GFR: Hyperthyroidism can cause an increase in GFR, which may seem beneficial but can lead to increased renal blood flow and potential damage to the glomeruli (the filtering units of the kidneys). Electrolyte Imbalances: Hyperthyroidism can cause imbalances in electrolytes such as calcium and phosphate, which are essential for proper kidney function. Elevated calcium levels (hypercalcemia) can lead to kidney stones and impaired kidney function. Proteinuria: Hyperthyroidism can cause protein to leak into the urine (proteinuria), which is a sign of kidney damage. Chronic proteinuria can lead to further kidney damage and a decline in kidney function. The Impact of Thyroid Disorders on the Urinary Tract In addition to their effects on the kidneys, thyroid disorders can also impact the urinary tract. The urinary tract includes the kidneys, ureters, bladder, and urethra, and it is responsible for the production, storage, and elimination of urine. Hypothyroidism and the Urinary Tract Urinary Retention: Hypothyroidism can cause urinary retention, a condition where the bladder does not empty completely. This can lead to increased risk of urinary tract infections (UTIs) and bladder dysfunction. Decreased Bladder Capacity: Hypothyroidism can reduce bladder capacity, leading to frequent urination and an increased risk of UTIs. Hyperthyroidism and the Urinary Tract Increased Urine Output (Polyuria): Hyperthyroidism can lead to increased urine production, a condition known as polyuria. This can result in frequent urination and dehydration if fluid intake is not adequately increased. Increased Risk of UTIs: Hyperthyroidism can increase the risk of urinary tract infections due to changes in urinary patterns and possible alterations in immune function. The Importance of Early Diagnosis and Comprehensive Treatment Given the complex relationship between thyroid function and kidney and urinary tract health, early diagnosis and comprehensive treatment of thyroid disorders are essential. Healthcare providers should be aware of the potential renal and urinary complications associated with thyroid disorders and take a holistic approach to patient care. Diagnosis and Management Diagnosis Diagnosing thyroid disorders involves a combination of clinical evaluation, laboratory tests, and imaging studies. Common diagnostic tests include: Thyroid Function Tests: These blood tests measure levels of TSH, T4, and T3. Elevated TSH and low T4 indicate hypothyroidism, while low TSH and high T4 indicate hyperthyroidism. Antibody Tests: These tests detect antibodies associated with autoimmune thyroid disorders, such as anti-thyroid peroxidase (anti-TPO) antibodies in Hashimoto's thyroiditis and thyroid-stimulating immunoglobulins (TSIs) in Graves' disease. Imaging Studies: Ultrasound and radioactive iodine uptake tests can help evaluate the structure and function of the thyroid gland. Management The management of thyroid disorders involves a combination of medication, lifestyle changes, and regular monitoring. Treatment strategies include: Medication: Hypothyroidism is typically treated with synthetic thyroid hormone replacement (levothyroxine). Hyperthyroidism may be treated with anti-thyroid medications (methimazole or propylthiouracil), radioactive iodine therapy, or surgery. Lifestyle Changes: Maintaining a healthy diet, regular exercise, and stress management can help support thyroid function and overall health. Regular Monitoring: Patients with thyroid disorders should undergo regular monitoring of thyroid function tests to ensure that treatment is effective and to adjust medications as needed. Addressing Kidney and Urinary Tract Health: Patients with thyroid disorders should also have their kidney function and urinary health monitored regularly. This may include blood tests to assess kidney function, urine tests to detect proteinuria or infection, and imaging studies if necessary. The Role of Specialist Care at Ace Hospital At Ace Hospital, we understand the intricate connections between thyroid health, kidney function, and urinary tract health. Our team of specialists in nephrology, urology, and endocrinology work together to provide comprehensive care for patients with thyroid disorders. Our multidisciplinary approach ensures that all aspects of a patient's health are addressed, leading to better outcomes and improved quality of life. Conclusion The relationship between thyroid disorders and kidney and urinary tract health is complex and multifaceted. Understanding this connection is crucial for providing comprehensive care to patients with thyroid issues. By recognizing the potential impact of thyroid disorders on kidney and urinary function, healthcare providers can take a holistic approach to diagnosis and treatment, ensuring that patients receive the best possible care. At Ace Hospital, we are committed to providing expert care for thyroid, kidney, and urinary tract health. Our team of specialists is dedicated to helping patients manage their conditions and improve their overall well-being. If you have concerns about your thyroid health or its impact on your kidneys and urinary tract, contact us today to schedule a consultation with our experienced team. |
2024.06.01 08:28 Background_Boss_1766 Dr. Sharda: Your Premier Skin Specialist Near You
When it comes to addressing your skin concerns, finding a trusted and experienced professional is essential. If you’re searching for a “Skin Specialist near me,” look no further than Dr. Sharda. With a wealth of experience and a deep commitment to patient care, Dr. Sharda stands out as a leading dermatologist in your area.
Expertise and Services
Dr. Sharda mundel brings years of expertise in dermatology, providing comprehensive care for a wide range of skin conditions. Whether you are dealing with acne, eczema, psoriasis, or seeking advanced anti-aging treatments, Dr. Sharda offers personalized treatment plans tailored to your specific needs. Here are some of the key services provided:
Acne Treatment: From mild to severe cases, Dr. Sharda employs the latest techniques and medications to effectively manage and treat acne, preventing future breakouts and reducing scarring. Anti-Aging Solutions: Utilizing cutting-edge technology, Dr. Sharda offers various anti-aging treatments, including chemical peels, microdermabrasion, and laser therapy, to help you achieve youthful and radiant skin. Psoriasis and Eczema Management: With a compassionate approach, Dr. Sharda provides effective management plans for chronic skin conditions like psoriasis and eczema, ensuring comfort and improved quality of life. Skin Cancer Screening and Treatment: Early detection is crucial. Dr. Sharda performs thorough skin examinations to identify any signs of skin cancer, offering prompt and effective treatment options if necessary. Cosmetic Dermatology: Enhance your natural beauty with cosmetic procedures such as Botox, fillers, and skin rejuvenation treatments, all administered with precision and care by Dr. Sharda.
Patient-Centered Approach
Dr. Sharda is known for her patient-centered approach, taking the time to understand each patient’s concerns and goals. She believes in educating her patients about their skin health, empowering them to make informed decisions about their treatments. This dedication to patient education and personalized care sets Dr. Sharda apart as a preferred “Skin Specialist near me” for many satisfied patients.
State-of-the-Art Facility
The clinic, conveniently located for those searching for a “Skin Specialist near me,” is equipped with the latest dermatological technology and tools. This ensures that patients receive the most advanced and effective treatments available. The welcoming and professional environment of the clinic further enhances the patient experience, making every visit comfortable and stress-free.
Testimonials
Patients consistently praise Dr. Sharda for her expertise, compassion, and outstanding results. Here are a few testimonials from satisfied patients:
“Dr. Sharda has transformed my skin! Her treatments are effective, and she genuinely cares about her patients.” — Sarah M. -“I finally found a dermatologist who listens and provides solutions that work. Dr. Sharda is the best!” — John D. “Highly recommend Dr. Sharda for anyone looking for a skin specialist near them. She is knowledgeable, friendly, and professional.” — Emily R.
Convenient Appointment Scheduling
Understanding the busy lives of her patients, Dr. Sharda offers flexible appointment scheduling, including evening and weekend slots. Booking an appointment is easy, with options for online scheduling or a quick call to the clinic.
When searching for a “Skin Specialist near me,” Dr. Sharda’s expertise, compassionate care, and state-of-the-art treatments make her the top choice. Take the first step towards healthier, more beautiful skin by scheduling a consultation with Dr. Sharda today. Your skin deserves the best, and with Dr. Sharda, that’s exactly what you’ll get.
submitted by Background_Boss_1766 to u/Background_Boss_1766 [link] [comments]
Expertise and Services
Dr. Sharda mundel brings years of expertise in dermatology, providing comprehensive care for a wide range of skin conditions. Whether you are dealing with acne, eczema, psoriasis, or seeking advanced anti-aging treatments, Dr. Sharda offers personalized treatment plans tailored to your specific needs. Here are some of the key services provided:
Acne Treatment: From mild to severe cases, Dr. Sharda employs the latest techniques and medications to effectively manage and treat acne, preventing future breakouts and reducing scarring. Anti-Aging Solutions: Utilizing cutting-edge technology, Dr. Sharda offers various anti-aging treatments, including chemical peels, microdermabrasion, and laser therapy, to help you achieve youthful and radiant skin. Psoriasis and Eczema Management: With a compassionate approach, Dr. Sharda provides effective management plans for chronic skin conditions like psoriasis and eczema, ensuring comfort and improved quality of life. Skin Cancer Screening and Treatment: Early detection is crucial. Dr. Sharda performs thorough skin examinations to identify any signs of skin cancer, offering prompt and effective treatment options if necessary. Cosmetic Dermatology: Enhance your natural beauty with cosmetic procedures such as Botox, fillers, and skin rejuvenation treatments, all administered with precision and care by Dr. Sharda.
Patient-Centered Approach
Dr. Sharda is known for her patient-centered approach, taking the time to understand each patient’s concerns and goals. She believes in educating her patients about their skin health, empowering them to make informed decisions about their treatments. This dedication to patient education and personalized care sets Dr. Sharda apart as a preferred “Skin Specialist near me” for many satisfied patients.
State-of-the-Art Facility
The clinic, conveniently located for those searching for a “Skin Specialist near me,” is equipped with the latest dermatological technology and tools. This ensures that patients receive the most advanced and effective treatments available. The welcoming and professional environment of the clinic further enhances the patient experience, making every visit comfortable and stress-free.
Testimonials
Patients consistently praise Dr. Sharda for her expertise, compassion, and outstanding results. Here are a few testimonials from satisfied patients:
“Dr. Sharda has transformed my skin! Her treatments are effective, and she genuinely cares about her patients.” — Sarah M. -“I finally found a dermatologist who listens and provides solutions that work. Dr. Sharda is the best!” — John D. “Highly recommend Dr. Sharda for anyone looking for a skin specialist near them. She is knowledgeable, friendly, and professional.” — Emily R.
Convenient Appointment Scheduling
Understanding the busy lives of her patients, Dr. Sharda offers flexible appointment scheduling, including evening and weekend slots. Booking an appointment is easy, with options for online scheduling or a quick call to the clinic.
When searching for a “Skin Specialist near me,” Dr. Sharda’s expertise, compassionate care, and state-of-the-art treatments make her the top choice. Take the first step towards healthier, more beautiful skin by scheduling a consultation with Dr. Sharda today. Your skin deserves the best, and with Dr. Sharda, that’s exactly what you’ll get.
2024.06.01 06:06 Ladysupersizedbitch Diagnosed with pneumonia 2 Sundays ago. Thought I was slowly getting better, but I’ve started seeing blood in the stuff I’m coughing up?
26 female. Major diagnoses: congestive heart failure as a result of illness (covid) from 2022.
Smaller diagnoses: chronic migraines, some mental illness.
I take a slew of meds for heart failure and depression/anxiety; I’ll provide a list if someone thinks it’s relevant.
May 15th, I started a dry cough. Symptoms worsened over the next few days (the usual: runny nose, sore throat, coughing horribly, fever, shortness of breath) until I finally went to the ER on May 19th. They said I had pneumonia and told me to come back on a hair trigger if I felt like I was getting worse. They administered doxycycline via IV and gave me two azithromycin pills; sent me home with a prescription for six more azithromycin to be taken once a day, along with a script for an albuterol inhaler.
That said…my dad had a nebulizer breathing treatment machine thing and tubes of albuterol for it. He hasn’t used it in a while so he sterilized it and gave it to me because I was having such a bad time trying to breathe that first week. I’ve done 3?4? treatments with it, one or two that first week (not anymore because I just never felt like cleaning and setting it up each time, I felt that bad), and 2 in the last two days when my mom forced me to bc by the end of the day I’m still struggling to breathe.
I really should have gone back to the ER, because I DID get worse in those few days after leaving the ER, but I did not want to be admitted to the hospital after what happened last time. Looking back I wish I had; these last couple weeks have SUCKED.
I’ve since improved, but still been coughing pretty frequently and having a runny nose. This entire time I’ve been coughing up mucous that’s varied from clear to yellow. I’ve also been sneezing up very thick yellow or white mucous.
This morning, after doing an albuterol breathing treatment last night, I coughed up more mucous. For the most part it was clear, but I saw some flecks of blood, which was odd. A little bit later I coughed so more up and there was still some blood flecks. No big deal, whatever, I’ve been able to breathe pretty well today.
However, it’s late now and I just coughed up so more mucous with a significantly more prominent blood spot in it. The mucous is pretty obviously pinkish red with a couple of flecks of bright blood. It was significant enough that I could taste the iron when it came up.
Should I be worried or is this normal? The ER doc didn’t really tell me what to expect as far as recovery goes; I think he expected me to come back…
submitted by Ladysupersizedbitch to AskDocs [link] [comments]
Smaller diagnoses: chronic migraines, some mental illness.
I take a slew of meds for heart failure and depression/anxiety; I’ll provide a list if someone thinks it’s relevant.
May 15th, I started a dry cough. Symptoms worsened over the next few days (the usual: runny nose, sore throat, coughing horribly, fever, shortness of breath) until I finally went to the ER on May 19th. They said I had pneumonia and told me to come back on a hair trigger if I felt like I was getting worse. They administered doxycycline via IV and gave me two azithromycin pills; sent me home with a prescription for six more azithromycin to be taken once a day, along with a script for an albuterol inhaler.
That said…my dad had a nebulizer breathing treatment machine thing and tubes of albuterol for it. He hasn’t used it in a while so he sterilized it and gave it to me because I was having such a bad time trying to breathe that first week. I’ve done 3?4? treatments with it, one or two that first week (not anymore because I just never felt like cleaning and setting it up each time, I felt that bad), and 2 in the last two days when my mom forced me to bc by the end of the day I’m still struggling to breathe.
I really should have gone back to the ER, because I DID get worse in those few days after leaving the ER, but I did not want to be admitted to the hospital after what happened last time. Looking back I wish I had; these last couple weeks have SUCKED.
I’ve since improved, but still been coughing pretty frequently and having a runny nose. This entire time I’ve been coughing up mucous that’s varied from clear to yellow. I’ve also been sneezing up very thick yellow or white mucous.
This morning, after doing an albuterol breathing treatment last night, I coughed up more mucous. For the most part it was clear, but I saw some flecks of blood, which was odd. A little bit later I coughed so more up and there was still some blood flecks. No big deal, whatever, I’ve been able to breathe pretty well today.
However, it’s late now and I just coughed up so more mucous with a significantly more prominent blood spot in it. The mucous is pretty obviously pinkish red with a couple of flecks of bright blood. It was significant enough that I could taste the iron when it came up.
Should I be worried or is this normal? The ER doc didn’t really tell me what to expect as far as recovery goes; I think he expected me to come back…
2024.06.01 05:52 Consistent_Foot_6657 Weight lifted, finally free
I am so excited to finally post my success story on here, I have been in this community for 2 years of my 3 years teaching. It has been such a motivator, and helped me discover my next steps.
Today I gathered all of my personal items, turned in my keys for my check out list, and as I walked down the hall and out the doors, I felt a weight that has been lifted from 4 years (including student teaching) of this stressful career I chose. I will be turning in my resignation letter next week, the same week I start my new job working at a spa where I will be a massage therapist.
This has not been easy. The first day I started student teaching I had a bad feeling in my gut. This job requires me to act against my nature as a human. My anxiety ramped up my first year, where I discovered my chronic pain caused by stress in my neck, and my dependence on alcohol to deal with stress that started during the pandemic and got out of control because students. From panic applying to hundreds of random jobs, and hearing nothing back my second year. Then the third year where I gained weight, drank heavily, and had thoughts of unaliving myself. And finally doing some inner soul searching my third year to ask myself “what do I want?” With the help of therapy.
How did I choose my next career? Like I said, I was applying to anything under the sun and heard nothing in return. Ironically, massage was my only healthy coping mechanism for my Chronic pain and anxiety that helped me as a teacher. I remember one particular session over winter break, when I was dreading going back to school, I was thinking about what a nice work environment my therapist had. Quiet, clean, minimal stimulation from noises, dealing with one client at a time, helping people relax. It was an aha moment. I did some research, found that I can make what I currently make, and more. Looked into job prospects, the industry is booming. Saw there was a 6 month night school program that I could be finished with this summer so I would not have to go back next year. And this is where I knew I was so uncomfortable with where I was in my life that I was willing to risk all of the negatives. The sunken cost fallacy of my degree, the possibility of not having health insurance for a while, not knowing if I would even like it, the general uncertainty of it all!
But let me tell you it is worth it. I found the perfect job, 5 minutes from my house. No more long commutes. I will be making slightly less, but will have health and retirement benefits which also include access to the chain of hotels and spas all over the country. I will be working this summer, but I have a vacation planned in the fall when plane prices are cheaper and less people are traveling!
On a side note, I can see a much healthier change in myself. I am working towards sobriety, which is a change that has paralleled this whole transition, and for me it has everything to do with the mental switch of taking control of where my life is headed. I think the environment I worked in was very toxic where principals and teachers supported drinking it away with adult beverages and getting a membership card at the liquor store. Always putting my emotional needs on the back burner for the sake of students. Numbing myself because I felt so overstimulated and overwhelmed that it was the only way to turn everything off at the end of the day.
There is a whole other world out there. I know the job market is tough, but if you can find your aha moment of a career change that would make you happier, start the night school! I understand not everyone has the privilege of doing so, but I also think you should really take into consideration your best interests, especially if you are feeling similar to me or others here.
TLDR: I am no longer wasting away, I have finally quit teaching, am working on quitting alcohol (which was my crutch as a teacher), and taking control of my life to move forward with a new career, and there is no feeling like it. Please join me!
submitted by Consistent_Foot_6657 to TeachersInTransition [link] [comments]
Today I gathered all of my personal items, turned in my keys for my check out list, and as I walked down the hall and out the doors, I felt a weight that has been lifted from 4 years (including student teaching) of this stressful career I chose. I will be turning in my resignation letter next week, the same week I start my new job working at a spa where I will be a massage therapist.
This has not been easy. The first day I started student teaching I had a bad feeling in my gut. This job requires me to act against my nature as a human. My anxiety ramped up my first year, where I discovered my chronic pain caused by stress in my neck, and my dependence on alcohol to deal with stress that started during the pandemic and got out of control because students. From panic applying to hundreds of random jobs, and hearing nothing back my second year. Then the third year where I gained weight, drank heavily, and had thoughts of unaliving myself. And finally doing some inner soul searching my third year to ask myself “what do I want?” With the help of therapy.
How did I choose my next career? Like I said, I was applying to anything under the sun and heard nothing in return. Ironically, massage was my only healthy coping mechanism for my Chronic pain and anxiety that helped me as a teacher. I remember one particular session over winter break, when I was dreading going back to school, I was thinking about what a nice work environment my therapist had. Quiet, clean, minimal stimulation from noises, dealing with one client at a time, helping people relax. It was an aha moment. I did some research, found that I can make what I currently make, and more. Looked into job prospects, the industry is booming. Saw there was a 6 month night school program that I could be finished with this summer so I would not have to go back next year. And this is where I knew I was so uncomfortable with where I was in my life that I was willing to risk all of the negatives. The sunken cost fallacy of my degree, the possibility of not having health insurance for a while, not knowing if I would even like it, the general uncertainty of it all!
But let me tell you it is worth it. I found the perfect job, 5 minutes from my house. No more long commutes. I will be making slightly less, but will have health and retirement benefits which also include access to the chain of hotels and spas all over the country. I will be working this summer, but I have a vacation planned in the fall when plane prices are cheaper and less people are traveling!
On a side note, I can see a much healthier change in myself. I am working towards sobriety, which is a change that has paralleled this whole transition, and for me it has everything to do with the mental switch of taking control of where my life is headed. I think the environment I worked in was very toxic where principals and teachers supported drinking it away with adult beverages and getting a membership card at the liquor store. Always putting my emotional needs on the back burner for the sake of students. Numbing myself because I felt so overstimulated and overwhelmed that it was the only way to turn everything off at the end of the day.
There is a whole other world out there. I know the job market is tough, but if you can find your aha moment of a career change that would make you happier, start the night school! I understand not everyone has the privilege of doing so, but I also think you should really take into consideration your best interests, especially if you are feeling similar to me or others here.
TLDR: I am no longer wasting away, I have finally quit teaching, am working on quitting alcohol (which was my crutch as a teacher), and taking control of my life to move forward with a new career, and there is no feeling like it. Please join me!
2024.06.01 04:47 Empathy2024 I Need a Dignified Plan
CONSIDERING MY PEGASUS SWITZERLAND OPTIONS AND WELCOME CONVERSATIONS
CONSIDERING A TRIP TO SWITZERLAND FOR INITIAL FACT FINDING
LOOKING FOR THISE APPROVED WHO WANT TO SHARE THEIR JOURNEY
I am well into my 50’s, in US, have chronic and severe neuropathy pain paired with severe anxiety and depression due to not being able to work or care for myself properly. I used to have a lot of friends, but, I’m no longer that strong, energetic, adventurous, giving friend.
I have had a full beautiful life, but, now I’m alone with zero quality of life. I lost almost everything I love, my partner, my pet, my home, my friends, and most of my belongings. I have one family member, a sister that I now only cause mostly worry & burden. She and her family do not want me to live with them, so I live alone and solidarity, mostly bedridden. Yes, I have had 10 years of exhaustive medications and therapy for my conditions. I’m still going to give a few more therapies a try, but, the road ahead is grim. I have enough money to survive OK right now and to visit Switzerland.
I was briefly homeless and tasted where I may end up realistically, so I think it is very responsible to explore my options before my life/health gets worse. I suffer daily and would fight harder to give back and volunteer to still have a good use, but, I am failing at the attempt. I am not physically strong enough.
There are a few therapeutic approaches that have helped pain, functioning,, and depression in the past, namely Ketamine IV Infusions. They are costly and don’t always work. Going to give them another try. THESE have been effective for chronic pain conditions and behavioral health conditions. But, the effects don’t last.
My heart goes out to all who are considering a self-determined future. I respect and appreciate the appositions’ arguments. Yes, there are valid concerns and vetting stipulations and safeguards in the dignity laws are valid and necessary.
My stance; People DO end up homeless, disabled, penniless, terrified, alone…basically in their own version of the painting “The Scream”I did. Literally, sleeping on the street and NOBODY deserves that fate.
That might be my future again and that reality is both realistic and unconscionable. I am not suicidal, but, I would challenge anyone to live on the street disabled for a few weeks.
There ARE human experiences worse than it’s conclusion.
If I deteriorate further, I need to have a plan…a self-determined dignified plan. I would welcome information from anyone who is personally knowledgeable of the process in Switzerland.
submitted by Empathy2024 to ProEuthanasia [link] [comments]
CONSIDERING A TRIP TO SWITZERLAND FOR INITIAL FACT FINDING
LOOKING FOR THISE APPROVED WHO WANT TO SHARE THEIR JOURNEY
I am well into my 50’s, in US, have chronic and severe neuropathy pain paired with severe anxiety and depression due to not being able to work or care for myself properly. I used to have a lot of friends, but, I’m no longer that strong, energetic, adventurous, giving friend.
I have had a full beautiful life, but, now I’m alone with zero quality of life. I lost almost everything I love, my partner, my pet, my home, my friends, and most of my belongings. I have one family member, a sister that I now only cause mostly worry & burden. She and her family do not want me to live with them, so I live alone and solidarity, mostly bedridden. Yes, I have had 10 years of exhaustive medications and therapy for my conditions. I’m still going to give a few more therapies a try, but, the road ahead is grim. I have enough money to survive OK right now and to visit Switzerland.
I was briefly homeless and tasted where I may end up realistically, so I think it is very responsible to explore my options before my life/health gets worse. I suffer daily and would fight harder to give back and volunteer to still have a good use, but, I am failing at the attempt. I am not physically strong enough.
There are a few therapeutic approaches that have helped pain, functioning,, and depression in the past, namely Ketamine IV Infusions. They are costly and don’t always work. Going to give them another try. THESE have been effective for chronic pain conditions and behavioral health conditions. But, the effects don’t last.
My heart goes out to all who are considering a self-determined future. I respect and appreciate the appositions’ arguments. Yes, there are valid concerns and vetting stipulations and safeguards in the dignity laws are valid and necessary.
My stance; People DO end up homeless, disabled, penniless, terrified, alone…basically in their own version of the painting “The Scream”I did. Literally, sleeping on the street and NOBODY deserves that fate.
That might be my future again and that reality is both realistic and unconscionable. I am not suicidal, but, I would challenge anyone to live on the street disabled for a few weeks.
There ARE human experiences worse than it’s conclusion.
If I deteriorate further, I need to have a plan…a self-determined dignified plan. I would welcome information from anyone who is personally knowledgeable of the process in Switzerland.
2024.06.01 04:36 Nightmaresmadeeasy Co parenting is hard -edit for name showing
 | submitted by Nightmaresmadeeasy to AutismTranslated [link] [comments] |
2024.06.01 03:08 Conscious_Shoe_756 Underrated treatment methods for malar bags caused by filler
I’ve posted a few times on here so I apologize for the spam lol. I’ve read at least 90% of cases of malar edema are related to previous HA filler injections (or other cosmetic procedures that resulted in a lot of swelling), so I wanted to help y’all out as someone who has been experiencing this. For reference, I naturally have some malar edema (very mild) bc I have rosacea and allergies, but the undereye/cheek filler I got a few months ago (less than half of a syringe) made it way worse.
1) Get an ultrasound of your face. It turned out I had a very small filler bubble that had migrated into the subcutaneous fat of my malar area and had become entangled in my blood vessels, causing a sh*t load of inflammation. I had dissolved twice before I went for ultrasound, so it’s more than likely that whatever dissolver you’ve had so far is not targeting everything.
2) Red Light Therapy. 10 mins/day, 5x/week. Only use clinically proven wavelengths (I recommend Omnilux Contour). It works if a big part of your issue is a sustained inflammatory reaction to the now-dissolved filler or an inflammatory reaction to the hyaluronidase. For a lot of people who have successfully dissolved all their filler, persistent swelling is due to inflammation. This truly helps over time with basically none of the side effects or rebound concerns of steroids.
3) Get your preexisting conditions under control. Rosacea: Low-dose doxycycline prescription ASAP, Azelaic Acid 15%. Allergies: daily antihistamine, Flonase, sinus rinses (with sterile water).
4) Kinesiology tape. Taping the malar area gently, in an upward vector (taping in an upward angle toward your temple/outer corner of eye) and wearing overnight, every night for 3 months has been proven clinically to significantly reduce severe festoons. Get good quality tape that won’t irritate your skin whenever you remove it. Malar edema is static lymphatic fluid and the tape encourages it to move out.
5) Working out your orbicularis muscle. Squint your eyes, really activating your lower eyelid to the point your malar area appears to be quaking from the muscle tension when you gently touch it, hold for 2-3 seconds, then release. Do 10 times, and repeat several times a day. This will also encourage lymphatic drainage.
6) Serrapeptase/nattokinase supplements. Talk to your doctor first. Doctor’s Best brand is highly recommended. Start w 40k SPU serra, 2k FU natto, can increase gradually if you feel necessary. Take once a day at least 2-3 hours after last meal, and wait 30 mins-1 hour before eating again. This can rapidly reduce inflammation, and gradually reduce fibrotic tissue (common cause of sustained edema for people who had long-term filler). Can cause gastrointestinal side effects so important to consult with doctor.
I incorporated most (but not all) of these strats and saw noticeable improvement of my stagnant edema within a few days. Hope these help! Nuclear methods include Morpheus, intralesional kenalog/triamcinolone, or doxy injections, but the outcomes from these procedures are very provider-dependent and carry a lot more risk than the above. I would recommend trying low-dose, diluted intralesional (directly in malar area) triamcinolone from a board-certified derm or plastic surgeon before Morpheus or doxy.
submitted by Conscious_Shoe_756 to MalarBags [link] [comments]
1) Get an ultrasound of your face. It turned out I had a very small filler bubble that had migrated into the subcutaneous fat of my malar area and had become entangled in my blood vessels, causing a sh*t load of inflammation. I had dissolved twice before I went for ultrasound, so it’s more than likely that whatever dissolver you’ve had so far is not targeting everything.
2) Red Light Therapy. 10 mins/day, 5x/week. Only use clinically proven wavelengths (I recommend Omnilux Contour). It works if a big part of your issue is a sustained inflammatory reaction to the now-dissolved filler or an inflammatory reaction to the hyaluronidase. For a lot of people who have successfully dissolved all their filler, persistent swelling is due to inflammation. This truly helps over time with basically none of the side effects or rebound concerns of steroids.
3) Get your preexisting conditions under control. Rosacea: Low-dose doxycycline prescription ASAP, Azelaic Acid 15%. Allergies: daily antihistamine, Flonase, sinus rinses (with sterile water).
4) Kinesiology tape. Taping the malar area gently, in an upward vector (taping in an upward angle toward your temple/outer corner of eye) and wearing overnight, every night for 3 months has been proven clinically to significantly reduce severe festoons. Get good quality tape that won’t irritate your skin whenever you remove it. Malar edema is static lymphatic fluid and the tape encourages it to move out.
5) Working out your orbicularis muscle. Squint your eyes, really activating your lower eyelid to the point your malar area appears to be quaking from the muscle tension when you gently touch it, hold for 2-3 seconds, then release. Do 10 times, and repeat several times a day. This will also encourage lymphatic drainage.
6) Serrapeptase/nattokinase supplements. Talk to your doctor first. Doctor’s Best brand is highly recommended. Start w 40k SPU serra, 2k FU natto, can increase gradually if you feel necessary. Take once a day at least 2-3 hours after last meal, and wait 30 mins-1 hour before eating again. This can rapidly reduce inflammation, and gradually reduce fibrotic tissue (common cause of sustained edema for people who had long-term filler). Can cause gastrointestinal side effects so important to consult with doctor.
I incorporated most (but not all) of these strats and saw noticeable improvement of my stagnant edema within a few days. Hope these help! Nuclear methods include Morpheus, intralesional kenalog/triamcinolone, or doxy injections, but the outcomes from these procedures are very provider-dependent and carry a lot more risk than the above. I would recommend trying low-dose, diluted intralesional (directly in malar area) triamcinolone from a board-certified derm or plastic surgeon before Morpheus or doxy.
2024.06.01 02:33 Reach_Far 40M with $2.5mil NW, with chronic anxiety disorder throughout my life
I am 40M, have around $2.5M net worth, $1.2M is in real estate equity, the rest is in stock/401K/CD. I am making around $650k a year now.
I have chronic anxiety/OCD disorder since my adolescent, which becomes very bad in my 20s to 30s. It probably have to do with my personal traits of perfectionism. The anxiety symptom comes on and off and in the worst time it severely impact my quality of life and job. I am doing mindfulness and therapies and things are under control, but some times it can still relapse and then I just have severe intrusive thoughts and keep worrying about my job, life, future, kids and so on.
My current focus is to didicate the rest of my time to find good balance between work and life, and achieve true happiness and calm in my life.
submitted by Reach_Far to Fire [link] [comments]
I have chronic anxiety/OCD disorder since my adolescent, which becomes very bad in my 20s to 30s. It probably have to do with my personal traits of perfectionism. The anxiety symptom comes on and off and in the worst time it severely impact my quality of life and job. I am doing mindfulness and therapies and things are under control, but some times it can still relapse and then I just have severe intrusive thoughts and keep worrying about my job, life, future, kids and so on.
My current focus is to didicate the rest of my time to find good balance between work and life, and achieve true happiness and calm in my life.
2024.06.01 02:26 disgruntledjobseeker How do I explain my pain to others (autistic and need the right words)?
I am an autistic, optimistic person with chronic illness who recently got so many answers that I needed that eluded me for a long time-- and the help that I need. I need help explaining what I am experiencing to others.
I got a diagnosis, some treatment, an Occupational Therapy referral, and even an invitation to participate in a research study based on one of my new diagnoses. This is all great, and I am super happy about it.
What I am having troubles explaining to people is this increased need and desire to process things and clear my mind. My illness, Lyme, I have likely had for years. The congenital brain damage caused vision/movement issues I've had for literal decades. The knowledge that I have been struggling for so much time and had so little help is weighing heavily on me.
I still want to work and have been making progress on my own projects and critical tasks, but I also just feel extra touchy these days when people have time-sensitive requests. I find myself being impatient with members of my group project, and have troubles finishing my schoolwork as the quarter is wrapping up. Sometimes I just want to roll into a ball and cry "Leave me alone", but I don't actually want to be left alone-- I just want time to breathe and do things on my own time.
How do I explain this to people? What am I even feeling?
Edit: I do have a therapist who is awesome
submitted by disgruntledjobseeker to ChronicIllness [link] [comments]
I got a diagnosis, some treatment, an Occupational Therapy referral, and even an invitation to participate in a research study based on one of my new diagnoses. This is all great, and I am super happy about it.
What I am having troubles explaining to people is this increased need and desire to process things and clear my mind. My illness, Lyme, I have likely had for years. The congenital brain damage caused vision/movement issues I've had for literal decades. The knowledge that I have been struggling for so much time and had so little help is weighing heavily on me.
I still want to work and have been making progress on my own projects and critical tasks, but I also just feel extra touchy these days when people have time-sensitive requests. I find myself being impatient with members of my group project, and have troubles finishing my schoolwork as the quarter is wrapping up. Sometimes I just want to roll into a ball and cry "Leave me alone", but I don't actually want to be left alone-- I just want time to breathe and do things on my own time.
How do I explain this to people? What am I even feeling?
Edit: I do have a therapist who is awesome
2024.06.01 02:26 jacdan07 Surgery?
 | I’ve had a sinus infection for about 5 weeks. Have been on antibiotics as long as (amoxicillin, then doxycycline, then augmentin) - took the last dose 3 days ago. Got a sinus CT done today - everything but my frontal sinuses were full. ENT immediately scheduled me for endoscopic sinus surgery. submitted by jacdan07 to Sinusitis [link] [comments] I can breathe through my nose but it does get congested at night and my anosmia improved to about 40% of smell recovered. Is it me, or is surgery an overreaction? She listed me as having chronic pansinusitis, but it’s only been 5 weeks. I asked for a course of medrol to see if that helps before I do something that alters my life forever. I am 34 F, never had sinus issues outside of common cold before this. |
2024.06.01 02:03 leeser11 How do I believe in my self worth when I keep failing and being rejected?
I’m chronically ill, underemployed and live with my dad, am 38 with no career and I’m poor. My bf dumped me and now my friends are excluding/rejecting me. I try not to call myself a loser and believe that I am okay but everything outside of me is saying the opposite.
Halp? Yes I’m medicated and in therapy. Had a rough morning bc my friends seem to be giving me the slow fade and left me on read asking about getting together this weekend..
submitted by leeser11 to mentalhealth [link] [comments]
Halp? Yes I’m medicated and in therapy. Had a rough morning bc my friends seem to be giving me the slow fade and left me on read asking about getting together this weekend..
2024.06.01 01:49 4990 Preventative Cardiology (Part 4)
Preventative Cardiology Part 4: Insulin Resistance
Blood sugar (glucose) is tightly regulated in order to supply a constant stream of energy throughout the body. After a meal, insulin levels rise pushing glucose into cells, primarily in the liver and muscle. This glucose can be stored as glycogen or converted to fat. During fasting states, glucagon, cortisol, and other hormones act to release glucose into the blood ensuring a steady state of between 80-120 mg/dL.
In states of over-nutrition and obesity, blood glucose remains chronically elevated (hyperglycemia) and the body becomes resistant to the effects of insulin. This is called insulin resistance and highly associated with metabolic syndrome (discussed in detail later). Insulin resistance is the hallmark of type 2 diabetes. Importantly, chronically elevated blood glucose levels (and insulin), lead to macrovascular (large vessel) complications like heart attacks and strokes (ASCVD) as well as microvascular complciations (cataracts, kidney dysfunction, etc).
Measurements of insulin resistance include:
Fasting insulin levels can be measured along with the corresponding fasting glucose to derive the HOMA IR (see calculation). This is a frequently used measure of insulin resistance in research settings.
HbA1c is the most common indirect measurement of insulin resistance in clinical practice. It measures what percent of hemoglobin in the blood is glycated (glucose attached) and represents a 3 month running average of blood glucose levels. 5.7% corresponds to pre diabetes and 6.5% represents diabetes.
Triglyceride/Glucose is an extensively validated indirect measurement of insulin resistance mostly used for research as is Mets-IR.
Finally, continuous glucose monitors, which can estimate time in (healthy) range, excursions after meals, and many other derived metrics are increasingly important and give a higher level of granularity.
I check all these numbers in my routine practice because they give slightly different information and together paint a picture of a patients insulin sensitivity. It is critical to get right because again it is a major risk factor for ASCVD. Interventions for insulin resistance include Metformin, Fiber therapy, Diet, GLP1 agonists, among many other lifestyle and medical interventions.
In part 5, we will discuss hypertension (high blood pressure) as a major risk factor for ASCVD.
submitted by 4990 to healthylongevity [link] [comments]
Blood sugar (glucose) is tightly regulated in order to supply a constant stream of energy throughout the body. After a meal, insulin levels rise pushing glucose into cells, primarily in the liver and muscle. This glucose can be stored as glycogen or converted to fat. During fasting states, glucagon, cortisol, and other hormones act to release glucose into the blood ensuring a steady state of between 80-120 mg/dL.
In states of over-nutrition and obesity, blood glucose remains chronically elevated (hyperglycemia) and the body becomes resistant to the effects of insulin. This is called insulin resistance and highly associated with metabolic syndrome (discussed in detail later). Insulin resistance is the hallmark of type 2 diabetes. Importantly, chronically elevated blood glucose levels (and insulin), lead to macrovascular (large vessel) complications like heart attacks and strokes (ASCVD) as well as microvascular complciations (cataracts, kidney dysfunction, etc).
Measurements of insulin resistance include:
- Fasting Blood Glucose
- Insulin Levels (for HOMA-IR calculation)
- HbA1c (Glycated Hemoglobin)
- Triglyceride/Glucose Ratio
- Mets-IR
Fasting insulin levels can be measured along with the corresponding fasting glucose to derive the HOMA IR (see calculation). This is a frequently used measure of insulin resistance in research settings.
HbA1c is the most common indirect measurement of insulin resistance in clinical practice. It measures what percent of hemoglobin in the blood is glycated (glucose attached) and represents a 3 month running average of blood glucose levels. 5.7% corresponds to pre diabetes and 6.5% represents diabetes.
Triglyceride/Glucose is an extensively validated indirect measurement of insulin resistance mostly used for research as is Mets-IR.
Finally, continuous glucose monitors, which can estimate time in (healthy) range, excursions after meals, and many other derived metrics are increasingly important and give a higher level of granularity.
I check all these numbers in my routine practice because they give slightly different information and together paint a picture of a patients insulin sensitivity. It is critical to get right because again it is a major risk factor for ASCVD. Interventions for insulin resistance include Metformin, Fiber therapy, Diet, GLP1 agonists, among many other lifestyle and medical interventions.
In part 5, we will discuss hypertension (high blood pressure) as a major risk factor for ASCVD.
2024.06.01 00:54 imz72 Phase 2 stem cell trial by Hope Bio (non-profit organization) in Long COVID fails to achieve statistical significance
Hope Biosciences Research Foundation Announces Topline Results of Cell Therapy Clinical Trial in Long COVID
May 31, 2024
SUGAR LAND, Texas, May 31, 2024--(BUSINESS WIRE)--Houston-area clinical research organization Hope Biosciences Research Foundation (HBRF) today shares topline results of a randomized, placebo-controlled Phase II study (NCT05126563) to evaluate Hope Biosciences’ adipose‑derived allogeneic mesenchymal stem cell therapy (HB-adMSCs) for patients with Post‑COVID‑19 syndrome.
The trial enrolled 79 participants, with 39 subjects in the treatment group and 40 in the placebo group; 34 participants completed the study from the treatment group, and 30 from the placebo group. The 26-week study mandated four infusions of 200 million stem cells, for a total of 800 million cells.
The primary endpoint was a visual analog scale (VAS) test for fatigue, in which 68% of subjects in the treatment group showed significant improvement (p=.0002) and 63% of subjects in the placebo group showed significant improvement (p=.001). Differences between the treatment and placebo groups were not statistically significant. Treatment was safe and tolerable in both groups. Detailed analysis is now underway.
"Our previous pilot study (Adipose‑derived, autologous mesenchymal stem cell therapy for patients with post‑COVID‑19 syndrome: an intermediate‑size expanded access program) with N=10 subjects demonstrated highly significant improvements in treating the symptoms of patients with long-COVID," explains Ridhima Vij, Ph.D., Clinical Research Scientist, HBRF. "Consistent with those findings, the current trial shows significant improvements in long-COVID symptoms. However, an unexpectedly high placebo effect was observed, masking the treatment effects, with both groups exhibiting significant improvements. This unprecedented placebo response suggests a need for further investigation."
Headquartered in Sugar Land, Texas, HBRF is exploring the effects of high volume, sustained application of adult stem cells on diseases and conditions that currently have no cure and affect substantial portions of the American population.
In addition to COVID and long-COVID protocols, HBRF has conducted and is pursuing work in central nervous system conditions such as Parkinson’s Disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), cerebral palsy, spinal cord injury, polyneuropathy, muscular dystrophy, drug-resistant epilepsy, and ataxia.
To date HBRF has obtained FDA authorization for more than 35 clinical protocols in these and other conditions, including in lupus, chronic musculoskeletal pain, severe osteoarthritis, psoriatic arthritis, stroke, palliative care, and pancreatic cancer.
The study announced in this release is made possible in part due to support from The John S. Dunn Foundation. Learn more at hopebio.org.
https://finance.yahoo.com/news/hope-biosciences-research-foundation-announces-204100491.html
Note: Per the study's page on ClinicalTrials.gov, the ages eligible for the study were 18 Years to 70 Years.
submitted by imz72 to ATHX [link] [comments]
May 31, 2024
SUGAR LAND, Texas, May 31, 2024--(BUSINESS WIRE)--Houston-area clinical research organization Hope Biosciences Research Foundation (HBRF) today shares topline results of a randomized, placebo-controlled Phase II study (NCT05126563) to evaluate Hope Biosciences’ adipose‑derived allogeneic mesenchymal stem cell therapy (HB-adMSCs) for patients with Post‑COVID‑19 syndrome.
The trial enrolled 79 participants, with 39 subjects in the treatment group and 40 in the placebo group; 34 participants completed the study from the treatment group, and 30 from the placebo group. The 26-week study mandated four infusions of 200 million stem cells, for a total of 800 million cells.
The primary endpoint was a visual analog scale (VAS) test for fatigue, in which 68% of subjects in the treatment group showed significant improvement (p=.0002) and 63% of subjects in the placebo group showed significant improvement (p=.001). Differences between the treatment and placebo groups were not statistically significant. Treatment was safe and tolerable in both groups. Detailed analysis is now underway.
"Our previous pilot study (Adipose‑derived, autologous mesenchymal stem cell therapy for patients with post‑COVID‑19 syndrome: an intermediate‑size expanded access program) with N=10 subjects demonstrated highly significant improvements in treating the symptoms of patients with long-COVID," explains Ridhima Vij, Ph.D., Clinical Research Scientist, HBRF. "Consistent with those findings, the current trial shows significant improvements in long-COVID symptoms. However, an unexpectedly high placebo effect was observed, masking the treatment effects, with both groups exhibiting significant improvements. This unprecedented placebo response suggests a need for further investigation."
Headquartered in Sugar Land, Texas, HBRF is exploring the effects of high volume, sustained application of adult stem cells on diseases and conditions that currently have no cure and affect substantial portions of the American population.
In addition to COVID and long-COVID protocols, HBRF has conducted and is pursuing work in central nervous system conditions such as Parkinson’s Disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), cerebral palsy, spinal cord injury, polyneuropathy, muscular dystrophy, drug-resistant epilepsy, and ataxia.
To date HBRF has obtained FDA authorization for more than 35 clinical protocols in these and other conditions, including in lupus, chronic musculoskeletal pain, severe osteoarthritis, psoriatic arthritis, stroke, palliative care, and pancreatic cancer.
The study announced in this release is made possible in part due to support from The John S. Dunn Foundation. Learn more at hopebio.org.
https://finance.yahoo.com/news/hope-biosciences-research-foundation-announces-204100491.html